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Q8K9I6

- PNCB_BUCAP

UniProt

Q8K9I6 - PNCB_BUCAP

Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

    Catalytic activityi

    Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ligase activity Source: UniProtKB-KW
    2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
    3. nicotinate phosphoribosyltransferase activity Source: InterPro

    GO - Biological processi

    1. NAD biosynthetic process Source: UniProtKB-UniPathway
    2. nicotinate nucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase, Transferase

    Keywords - Biological processi

    Pyridine nucleotide biosynthesis

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-366-MONOMER.
    UniPathwayiUPA00253; UER00457.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
    Short name:
    NAPRTaseUniRule annotation
    Gene namesi
    Name:pncBUniRule annotation
    Ordered Locus Names:BUsg_349
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 398398Nicotinate phosphoribosyltransferasePRO_0000205824Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi198804.BUsg349.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K9I6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAPRTase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1488.
    KOiK00763.
    OMAiQAVFHRY.
    OrthoDBiEOG6X10XB.

    Family and domain databases

    HAMAPiMF_00570. NAPRTase.
    InterProiIPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view]
    PANTHERiPTHR11098. PTHR11098. 1 hit.
    PfamiPF04095. NAPRTase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000484. NAPRT. 1 hit.
    SUPFAMiSSF51690. SSF51690. 1 hit.
    TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8K9I6-1 [UniParc]FASTAAdd to Basket

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    MKQYNYPIVK TLLDTDAYKF YMQQAVFYHY KNVDVVAEFI CRGPNILGCY    50
    SHILLDQINM MSSLSLSHEE YLYMTTFPFF KKEYLHWLKK FRYNITQVKV 100
    DNYHGQLHIR ISGLWKEVIL WEVPILSLIS EIFHRHCYPE ITSNIAVQHL 150
    NKKLKEFFKK NRDVDLSRLK IVDFGTRRRF SYDVQYSIIK RLKDTFPFLI 200
    GSSNYHISRI LKLLPVGTQA HEWFQAHQQI SSNLRNSQTL ALKTWLSQYN 250
    QHLSIALTDC ITMDSFLRDF NLFFSKSYQG IRHDSGDPVK WGEKAIEHYE 300
    RLGIDPTTKT LLFSDNLNFR KMISLYKKFN NRVNIIFGIG TKLTCDIPNV 350
    KPLNIVIKLV KCNGKPVAKL SDSPGKTFCL DRNFIKSLCK AFDLSLTV 398
    Length:398
    Mass (Da):46,777
    Last modified:October 1, 2002 - v1
    Checksum:i19B29A2C1C6937CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67902.1.
    RefSeqiNP_660691.1. NC_004061.1.
    WP_011053869.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM67902; AAM67902; BUsg_349.
    GeneIDi1005807.
    KEGGibas:BUsg349.
    PATRICi21247513. VBIBucAph100086_0363.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67902.1 .
    RefSeqi NP_660691.1. NC_004061.1.
    WP_011053869.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali Q8K9I6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg349.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM67902 ; AAM67902 ; BUsg_349 .
    GeneIDi 1005807.
    KEGGi bas:BUsg349.
    PATRICi 21247513. VBIBucAph100086_0363.

    Phylogenomic databases

    eggNOGi COG1488.
    KOi K00763.
    OMAi QAVFHRY.
    OrthoDBi EOG6X10XB.

    Enzyme and pathway databases

    UniPathwayi UPA00253 ; UER00457 .
    BioCyci BAPH198804:GHMG-366-MONOMER.

    Family and domain databases

    HAMAPi MF_00570. NAPRTase.
    InterProi IPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view ]
    PANTHERi PTHR11098. PTHR11098. 1 hit.
    Pfami PF04095. NAPRTase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000484. NAPRT. 1 hit.
    SUPFAMi SSF51690. SSF51690. 1 hit.
    TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.

    Entry informationi

    Entry nameiPNCB_BUCAP
    AccessioniPrimary (citable) accession number: Q8K9I6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3