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Q8K9I6

- PNCB_BUCAP

UniProt

Q8K9I6 - PNCB_BUCAP

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, BUsg_349
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-366-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:BUsg_349
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 398398Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_0000205824Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg349.

Structurei

3D structure databases

ProteinModelPortaliQ8K9I6.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K9I6-1 [UniParc]FASTAAdd to Basket

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MKQYNYPIVK TLLDTDAYKF YMQQAVFYHY KNVDVVAEFI CRGPNILGCY    50
SHILLDQINM MSSLSLSHEE YLYMTTFPFF KKEYLHWLKK FRYNITQVKV 100
DNYHGQLHIR ISGLWKEVIL WEVPILSLIS EIFHRHCYPE ITSNIAVQHL 150
NKKLKEFFKK NRDVDLSRLK IVDFGTRRRF SYDVQYSIIK RLKDTFPFLI 200
GSSNYHISRI LKLLPVGTQA HEWFQAHQQI SSNLRNSQTL ALKTWLSQYN 250
QHLSIALTDC ITMDSFLRDF NLFFSKSYQG IRHDSGDPVK WGEKAIEHYE 300
RLGIDPTTKT LLFSDNLNFR KMISLYKKFN NRVNIIFGIG TKLTCDIPNV 350
KPLNIVIKLV KCNGKPVAKL SDSPGKTFCL DRNFIKSLCK AFDLSLTV 398
Length:398
Mass (Da):46,777
Last modified:October 1, 2002 - v1
Checksum:i19B29A2C1C6937CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67902.1.
RefSeqiNP_660691.1. NC_004061.1.
WP_011053869.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67902; AAM67902; BUsg_349.
GeneIDi1005807.
KEGGibas:BUsg349.
PATRICi21247513. VBIBucAph100086_0363.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67902.1 .
RefSeqi NP_660691.1. NC_004061.1.
WP_011053869.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q8K9I6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg349.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67902 ; AAM67902 ; BUsg_349 .
GeneIDi 1005807.
KEGGi bas:BUsg349.
PATRICi 21247513. VBIBucAph100086_0363.

Phylogenomic databases

eggNOGi COG1488.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci BAPH198804:GHMG-366-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiPNCB_BUCAP
AccessioniPrimary (citable) accession number: Q8K9I6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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