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Q8K9I6 (PNCB_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:BUsg_349
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205824

Sequences

Sequence LengthMass (Da)Tools
Q8K9I6 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 19B29A2C1C6937CF

FASTA39846,777
        10         20         30         40         50         60 
MKQYNYPIVK TLLDTDAYKF YMQQAVFYHY KNVDVVAEFI CRGPNILGCY SHILLDQINM 

        70         80         90        100        110        120 
MSSLSLSHEE YLYMTTFPFF KKEYLHWLKK FRYNITQVKV DNYHGQLHIR ISGLWKEVIL 

       130        140        150        160        170        180 
WEVPILSLIS EIFHRHCYPE ITSNIAVQHL NKKLKEFFKK NRDVDLSRLK IVDFGTRRRF 

       190        200        210        220        230        240 
SYDVQYSIIK RLKDTFPFLI GSSNYHISRI LKLLPVGTQA HEWFQAHQQI SSNLRNSQTL 

       250        260        270        280        290        300 
ALKTWLSQYN QHLSIALTDC ITMDSFLRDF NLFFSKSYQG IRHDSGDPVK WGEKAIEHYE 

       310        320        330        340        350        360 
RLGIDPTTKT LLFSDNLNFR KMISLYKKFN NRVNIIFGIG TKLTCDIPNV KPLNIVIKLV 

       370        380        390 
KCNGKPVAKL SDSPGKTFCL DRNFIKSLCK AFDLSLTV 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM67902.1.
RefSeqNP_660691.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K9I6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg349.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67902; AAM67902; BUsg_349.
GeneID1005807.
KEGGbas:BUsg349.
PATRIC21247513. VBIBucAph100086_0363.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-366-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_BUCAP
AccessionPrimary (citable) accession number: Q8K9I6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: May 14, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names