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Reviewed, UniProtKB/Swiss-Prot Q8K9H9 (PYRB_BUCAP)

Last modified June 16, 2009. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Aspartate carbamoyltransferase
    EC=2.1.3.2
Alternative name(s):
    Aspartate transcarbamylase
      Short name=ATCase
Gene names
Name: pyrB
Ordered Locus Names: BUsg_357
OrganismBuchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]
Taxonomic identifier98794 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP MF_00001

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 2/6. HAMAP MF_00001

Sequence similarities

Belongs to the ATCase/OTCase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 311311Aspartate carbamoyltransferase HAMAP MF_00001
PRO_0000113111

Sequences

Sequence LengthMass (Da)Tools
Q8K9H9-1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 4225C7BDDE2C11BD

FASTA31135,315
        10         20         30         40         50         60 
MRNSLYKKNI ISISDLNQNE LELVLKKSAF LKVKAQPNLL KNKIIASCFF EASTRTRLSF 

        70         80         90        100        110        120 
ETAVHRLGAS IIGFSDGSNI SLGKKGETLS DTISVISSYV DAIIIRHPQE GSARLAAQFS 

       130        140        150        160        170        180 
NGVPIFNAGD GANQHPTQTL LDLFTIKETQ NKLNNLNIAM VGDLKYGRTV HSLTQALAKY 

       190        200        210        220        230        240 
KNNQFFFVSP DSLTMPNYIN DMLYKKEIHW KRYKNIEEII SEIDILYMTR VQKERLDSTE 

       250        260        270        280        290        300 
YASAKSKFVL QTSTLKNARN NLKILHPLPR IDEIDNNVDF TPYAWYFKQA ANGIYARQAI 

       310 
LSLVLIEKHF E 

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References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

AE013218 Genomic DNA. Translation: AAM67910.1.
RefSeqNP_660699.1.

3D structure databases

HSSPHSSP built from PDB template 1GQ3 based on UniProtKB P00479.
ModBaseSearch...

Genome annotation databases

GeneID1005798.
GenomeReviewsGene locus BUsg_357 in contig AE013218_GR.
KEGGbas:BUsg357.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ8K9H9.
OMAQ8K9H9. LYTIREN.

Enzyme and pathway databases

BioCycBAPH198804:BUSG357-MON.

Family and domain databases

HAMAPMF_00001.
[Tree]
InterProIPR006132. Asp/Orn_carbamoyltranf_P_bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082. Aspartate_carbamoyltransf_euk.
[Graphical view]
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00101. ATCASE.
TIGRFAMsTIGR00670. asp_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRB_BUCAP
AccessionPrimary (citable) accession number: Q8K9H9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: June 16, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents