Q8K9H9 (PYRB_BUCAP) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 66.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Aspartate carbamoyltransferase EC=2.1.3.2 Alternative name(s): Aspartate transcarbamylase Short name=ATCase | ||||
| Gene names |
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| Organism | Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 198804 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera |
Protein attributes
| Sequence length | 311 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP MF_00001 |
| Pathway | Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP MF_00001 |
| Sequence similarities | Belongs to the ATCase/OTCase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Pyrimidine biosynthesis |
| Molecular function | Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | 'de novo' pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro cellular amino acid metabolic processInferred from electronic annotation. Source: InterPro pyrimidine nucleotide biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | amino acid binding Inferred from electronic annotation. Source: InterPro aspartate carbamoyltransferase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 311 | 311 | Aspartate carbamoyltransferase HAMAP MF_00001 | PRO_0000113111 | |||
Sequences
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References
| [1] | "50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE013218 Genomic DNA. Translation: AAM67910.1. |
| RefSeq | NP_660699.1. NC_004061.1. |
3D structure databases | |
| ProteinModelPortal | Q8K9H9. |
| SMR | Q8K9H9. Positions 3-305. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBUCT00000000481; EBBUCP00000000481; EBBUCG00000000481. |
| GeneID | 1005798. |
| GenomeReviews | Gene locus BUsg_357 in contig AE013218_GR. |
| KEGG | bas:BUsg357. |
| PATRIC | 21247529. VBIBucAph100086_0371. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000007871. |
| HOGENOM | HBG579429. |
| OMA | ADRYENT. |
| ProtClustDB | PRK00856. |
Enzyme and pathway databases | |
| BioCyc | BAPH198804:BUSG357-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00001. Asp_carb_tr. [Tree] |
| InterPro | IPR006132. Asp/Orn_carbamoyltranf_P-bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR006131. Asp_carbamoyltransf_Asp/Orn-bd. IPR002082. Asp_carbamoyltransf_euk. [Graphical view] |
| KO | K00609. |
| Pfam | PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view] |
| PRINTS | PR00100. AOTCASE. PR00101. ATCASE. |
| SUPFAM | SSF53671. Asp/Orn_carbamoyltranf. 1 hit. |
| TIGRFAMs | TIGR00670. Asp_carb_tr. 1 hit. |
| PROSITE | PS00097. CARBAMOYLTRANSFERASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PYRB_BUCAP | ||||||||
| Accession | Primary (citable) accession number: Q8K9H9 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Buchnera aphidicola (subsp. Schizaphis graminum) Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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