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Q8K9E2 (RPIA_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribose-5-phosphate isomerase A

EC=5.3.1.6
Alternative name(s):
Phosphoriboisomerase A
Short name=PRI
Gene names
Name:rpiA
Ordered Locus Names:BUsg_397
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate By similarity. HAMAP-Rule MF_00170

Catalytic activity

D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP-Rule MF_00170

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP-Rule MF_00170

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00170

Sequence similarities

Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpentose-phosphate shunt, non-oxidative branch

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribose-5-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 219219Ribose-5-phosphate isomerase A HAMAP-Rule MF_00170
PRO_0000158399

Regions

Region28 – 314Substrate binding By similarity
Region81 – 844Substrate binding By similarity
Region94 – 974Substrate binding By similarity

Sites

Active site1031Proton acceptor By similarity
Binding site1211Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8K9E2 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 8E417A07EFC6FDEA

FASTA21923,750
        10         20         30         40         50         60 
MNLNELKKKA AWAALDYIYP GTVIGVGTGS TVFYFIQALS TVKHLISGAV SSSNSSTVLL 

        70         80         90        100        110        120 
KKNGIRVLDL NTFDFLEIYV DSADEINNDM QMIKGGGAAL TKEKIIAAMS KKFVCIIDES 

       130        140        150        160        170        180 
KKVNILGTFP LPIEIIPIAF SYISKEILKI GGQPKLRENI ITDNGNVIID VYNLFINDPI 

       190        200        210 
SVEKKINSLP GVVSVGLFAS RVADVVLIGT QKGVEIIKN 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM67948.1.
RefSeqNP_660737.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K9E2.
SMRQ8K9E2. Positions 1-217.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg397.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67948; AAM67948; BUsg_397.
GeneID1005518.
KEGGbas:BUsg397.
PATRIC21247614. VBIBucAph100086_0410.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0120.
KOK01807.
OMAGACHVQE.
OrthoDBEOG67MF61.
ProtClustDBPRK00702.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-417-MONOMER.
UniPathwayUPA00115; UER00412.

Family and domain databases

HAMAPMF_00170. Rib_5P_isom_A.
InterProIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERPTHR11934. PTHR11934. 1 hit.
PfamPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsTIGR00021. rpiA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPIA_BUCAP
AccessionPrimary (citable) accession number: Q8K9E2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: February 19, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names