ID   CYSC_BUCAP              Reviewed;         211 AA.
AC   Q8K9D4;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   16-JUN-2009, entry version 48.
DE   RecName: Full=Adenylyl-sulfate kinase;
DE            EC=2.7.1.25;
DE   AltName: Full=APS kinase;
DE   AltName: Full=Adenosine-5'-phosphosulfate kinase;
DE   AltName: Full=ATP adenosine-5'-phosphosulfate 3'-phosphotransferase;
GN   Name=cysC; OrderedLocusNames=BUsg_407;
OS   Buchnera aphidicola subsp. Schizaphis graminum.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Buchnera.
OX   NCBI_TaxID=98794;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=22084549; PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- FUNCTION: Catalyzes the synthesis of activated sulfate.
CC   -!- CATALYTIC ACTIVITY: ATP + adenylyl sulfate = ADP + 3'-
CC       phosphoadenylyl sulfate.
CC   -!- PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite
CC       from sulfate: step 2/3.
CC   -!- SIMILARITY: Belongs to the APS kinase family.
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DR   EMBL; AE013218; AAM67957.1; -; Genomic_DNA.
DR   RefSeq; NP_660746.1; -.
DR   HSSP; Q12657; 1M7G.
DR   GeneID; 1005753; -.
DR   GenomeReviews; AE013218_GR; BUsg_407.
DR   KEGG; bas:BUsg407; -.
DR   HOGENOM; Q8K9D4; -.
DR   OMA; Q8K9D4; IITITAF.
DR   BioCyc; BAPH198804:BUSG407-MON; -.
DR   GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0000103; P:sulfate assimilation; IEA:HAMAP.
DR   HAMAP; MF_00065; -; 1.
DR   InterPro; IPR002891; APS_kinase_C.
DR   Pfam; PF01583; APS_kinase; 1.
DR   ProDom; PD002350; APS_kinase; 1.
DR   TIGRFAMs; TIGR00455; apsK; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW   Phosphoprotein; Transferase.
FT   CHAIN         1    211       Adenylyl-sulfate kinase.
FT                                /FTId=PRO_0000105906.
FT   NP_BIND      36     43       ATP (Potential).
FT   ACT_SITE    110    110       Phosphoserine intermediate (By
FT                                similarity).
SQ   SEQUENCE   211 AA;  24288 MW;  0644BA855D76B6B1 CRC64;
     MHNNSKKNII WQKHSVTRIK REQKNGHKSI VIWFTGLSGS GKSSIANSLE EILFQNNFNT
     YLLDGDNIRS SLCSDLSFSI LDRNENIRRI GEVSKLMIDA GIIVLVSVIS PYRNQRKKIR
     LMLGKINFLE VFVDTPLNIC EERDPKKLYQ KSRLGKISDL TGIQSLYEIP EKPDLHLDET
     ISLKNNTKKL IHILCDKNII SFPNIDETFL F
//