Reviewed, UniProtKB/Swiss-Prot Q8K9D1 (DSBA_BUCAP)

Names and origin

Protein names

Recommended name:
    Thiol:disulfide interchange protein dsbA

Gene names

Name:	dsbA
Ordered Locus Names:	BUsg_415

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins By similarity.
Sequence similarities	Belongs to the thioredoxin family. DsbA subfamily.

Ontologies

Keywords
Domain	Redox-active center Signal
PTM	Disulfide bond
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro
Cellular component	outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro
Molecular function	protein disulfide oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	By similarity
	Chain	20 – 209	190	Thiol:disulfide interchange protein dsbA		PRO_0000034249
Amino acid modifications
	Disulfide bond	49 ↔ 52		Redox-active By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8K9D1-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: D3A3F8EFEC3BF037	FASTA	209	25,137
	10 20 30 40 50 60 MKKILIVLYS IFLSFTASSY EFNNKKEYEI EKRNISNVPK VMHFFSFFCP YCYELEKIYN 70 80 90 100 110 120 IQSLIKNKID KKIKIQTYHV NFLGGEFSKI LTKIWIIAQK MKVEEKIMMP IFKEIQENNT 130 140 150 160 170 180 ISHTSNIKNI FLQKTGINKD QYNKFWNSFT IKMLIKKNDN DINKIKLNHV PTMIVNGKYV 190 200 IDYYKLEKIF KTNFSKKYIK LIKFLLSKK

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013218 Genomic DNA. Translation: AAM67960.1.
RefSeq	NP_660749.1.
3D structure databases
HSSP	HSSP built from PDB template 1A23 based on UniProtKB P24991.
ModBase	Search...
Genome annotation databases
GeneID	1005746.
GenomeReviews	Gene locus BUsg_415 in contig AE013218_GR.
KEGG	bas:BUsg415.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8K9D1.
OMA	Q8K9D1. SFYCHNC.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG415-MON.
Family and domain databases
InterPro	IPR001853. OxRdtase_DSBA. IPR017937. Thioredoxin_CS. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF01323. DSBA. 1 hit. [Graphical view]
PROSITE	PS00194. THIOREDOXIN_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DSBA_BUCAP

Accession

Primary (citable) accession number: Q8K9D1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)