Skip Header

Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q8K9C7 (KGUA_BUCAP)

Last modified February 9, 2010. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Guanylate kinase
    EC=2.7.4.8
Alternative name(s):
    GMP kinase
Gene names
Name: gmk
Ordered Locus Names: BUsg_419
OrganismBuchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]
Taxonomic identifier98794 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length207 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP MF_00328

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP MF_00328

Subcellular location

Cytoplasm By similarity HAMAP MF_00328.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

guanylate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 207207Guanylate kinase HAMAP MF_00328
PRO_0000170511

Regions

Domain4 – 184181Guanylate kinase-like
Nucleotide binding11 – 188ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8K9C7-1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 6C68A9D261F32F90

FASTA20724,153
        10         20         30         40         50         60 
MSQGILFIIS APSGTGKSSL IEGLLKTKFL YNIQVSISHT TRVMRPGESH GKHYYFISKK 

        70         80         90        100        110        120 
EFRIMIKQES FLEYAKVFNN YYGTSRQSIE KMLLSGIDVF LDIDWQGANQ IRYKMPNSKS 

       130        140        150        160        170        180 
IFLLPPSKDE LYKRLRERGQ DSDTVISKRM EKAVDEMNHY SEYDYLIIND DFQKAINDLR 

       190        200 
TIIIAEHLCL FHQKNKHNVL ISQLLKS 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM67964.1.
RefSeqNP_660753.1.

3D structure databases

SMRQ8K9C7. Positions 2-205.
ModBaseSearch...

Genome annotation databases

GeneID1005742.
GenomeReviewsGene locus BUsg_419 in contig AE013218_GR.
KEGGbas:BUsg419.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG671982.
OMADIDWQGT.

Enzyme and pathway databases

BioCycBAPH198804:BUSG419-MONOMER.

Family and domain databases

HAMAPMF_00328. Guanylate_kinase.
[Tree]
InterProIPR008144. Guanylate_kin.
IPR008145. Guanylate_kin/L-typ_Ca_channel.
IPR020590. Guanylate_kinase_CS.
IPR017665. Guanylate_kinase_sub.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_BUCAP
AccessionPrimary (citable) accession number: Q8K9C7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: February 9, 2010
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents