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Q8K9B7

- NADD_BUCAP

UniProt

Q8K9B7 - NADD_BUCAP

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Protein

Probable nicotinate-nucleotide adenylyltransferase

Gene
nadD, BUsg_431
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) By similarity.UniRule annotation

Catalytic activityi

ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD+.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. nicotinate-nucleotide adenylyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Keywords - Ligandi

ATP-binding, NAD, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-454-MONOMER.
UniPathwayiUPA00253; UER00332.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable nicotinate-nucleotide adenylyltransferase (EC:2.7.7.18)
Alternative name(s):
Deamido-NAD(+) diphosphorylase
Deamido-NAD(+) pyrophosphorylase
Nicotinate mononucleotide adenylyltransferase
Short name:
NaMN adenylyltransferase
Gene namesi
Name:nadD
Ordered Locus Names:BUsg_431
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 216216Probable nicotinate-nucleotide adenylyltransferaseUniRule annotationPRO_0000181399Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg431.

Structurei

3D structure databases

ProteinModelPortaliQ8K9B7.

Family & Domainsi

Sequence similaritiesi

Belongs to the NadD family.

Phylogenomic databases

eggNOGiCOG1057.
KOiK00969.
OMAiIQCAPAG.
OrthoDBiEOG6F55KJ.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00244. NaMN_adenylyltr.
InterProiIPR004821. Cyt_trans-like.
IPR005248. NAMN_adtrnsfrase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR12039. PTHR12039. 1 hit.
PfamiPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00125. cyt_tran_rel. 1 hit.
TIGR00482. TIGR00482. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K9B7-1 [UniParc]FASTAAdd to Basket

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MKEIYAIFGG NFDPIHYGHI TSAEKLSREI SIKKIILLPN YGPPHRSKTK    50
TSIIDRLKMI KFAIKDNKLF TISYLETKKN TTFYTIETLK KIRKKIGYLQ 100
PLCFIIGEDN LNNLNIWKDW KKILSLSHLL ICPRIHIKKS NPKLKKWISD 150
HTTKNSNLLH KKPFGFIFFS KMSMLNISST AIRKSYYEGK SACGLLPSKI 200
DKYILSKNLY KIYNQN 216
Length:216
Mass (Da):25,218
Last modified:October 1, 2002 - v1
Checksum:i74AE504B3F7F5CE6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67974.1.
RefSeqiNP_660763.1. NC_004061.1.
WP_011053941.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67974; AAM67974; BUsg_431.
GeneIDi1005732.
KEGGibas:BUsg431.
PATRICi21247712. VBIBucAph100086_0456.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67974.1 .
RefSeqi NP_660763.1. NC_004061.1.
WP_011053941.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q8K9B7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg431.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67974 ; AAM67974 ; BUsg_431 .
GeneIDi 1005732.
KEGGi bas:BUsg431.
PATRICi 21247712. VBIBucAph100086_0456.

Phylogenomic databases

eggNOGi COG1057.
KOi K00969.
OMAi IQCAPAG.
OrthoDBi EOG6F55KJ.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00332 .
BioCyci BAPH198804:GHMG-454-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_00244. NaMN_adenylyltr.
InterProi IPR004821. Cyt_trans-like.
IPR005248. NAMN_adtrnsfrase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR12039. PTHR12039. 1 hit.
Pfami PF01467. CTP_transf_2. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00125. cyt_tran_rel. 1 hit.
TIGR00482. TIGR00482. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiNADD_BUCAP
AccessioniPrimary (citable) accession number: Q8K9B7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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