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Protein

Cytochrome bo(3) ubiquinol oxidase subunit 2

Gene

cyoA

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Cytochrome bo3 ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-480-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome bo(3) ubiquinol oxidase subunit 2
Alternative name(s):
Cytochrome o ubiquinol oxidase subunit 2
Short name:
Cytochrome o subunit 2
Oxidase bo(3) subunit 2
Ubiquinol oxidase polypeptide II
Ubiquinol oxidase subunit 2
Gene namesi
Name:cyoA
Ordered Locus Names:BUsg_456
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini25 – 4218ExtracellularSequence AnalysisAdd
BLAST
Transmembranei43 – 6321HelicalSequence AnalysisAdd
BLAST
Topological domaini64 – 8724CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei88 – 10821HelicalSequence AnalysisAdd
BLAST
Topological domaini109 – 290182ExtracellularSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence AnalysisAdd
BLAST
Chaini25 – 290266Cytochrome bo(3) ubiquinol oxidase subunit 2PRO_0000006073Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi25 – 251N-palmitoyl cysteineSequence Analysis
Lipidationi25 – 251S-diacylglycerol cysteineSequence Analysis

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Subunit structurei

Heterooctamer of two A chains, two B chains, two C chains and two D chains.By similarity

Protein-protein interaction databases

STRINGi198804.BUsg456.

Structurei

3D structure databases

ProteinModelPortaliQ8K993.
SMRiQ8K993. Positions 125-281.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1622.
KOiK02297.
OMAiKYAMADM.
OrthoDBiEOG6PS5TJ.

Family and domain databases

Gene3Di1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProiIPR010514. COX_ARM.
IPR008972. Cupredoxin.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
IPR006333. Cyt_o_ubiquinol_oxidase_su2.
[Graphical view]
PfamiPF00116. COX2. 1 hit.
PF06481. COX_ARM. 1 hit.
[Graphical view]
PIRSFiPIRSF000292. Ubi_od_II. 1 hit.
SUPFAMiSSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
TIGRFAMsiTIGR01433. CyoA. 1 hit.
PROSITEiPS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8K993-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISINFNNFF KTLLLILIAF TLHGCDSILF NPHGIIAIQE CSILLISFLI
60 70 80 90 100
MLFVIIPVIF MTIYFSVKYR ASNINAKYKP DWCDSKKIEI IVWTIPISII
110 120 130 140 150
LFLAFVTWNY SHILDPKKSI ISKYKPIKID VVSLDWRWLF IYPEYHIATI
160 170 180 190 200
NEIMFPINRS IIFHITSNSV MNSFFIPSLG SQIYAMPGMM TTLNLMSNSP
210 220 230 240 250
GKYKGISSNY SGKGFSNMKF TAISVLNIKD FENWIKKAQQ SPKKLNKMSI
260 270 280 290
FNIISLPNEN HFIEYFSDVK KNLFYEIINQ TYSKNKVFKH
Length:290
Mass (Da):33,730
Last modified:October 1, 2002 - v1
Checksum:i3D80A02A84732963
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM67999.1.
RefSeqiWP_011053966.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67999; AAM67999; BUsg_456.
KEGGibas:BUsg456.
PATRICi21247766. VBIBucAph100086_0482.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM67999.1.
RefSeqiWP_011053966.1. NC_004061.1.

3D structure databases

ProteinModelPortaliQ8K993.
SMRiQ8K993. Positions 125-281.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198804.BUsg456.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM67999; AAM67999; BUsg_456.
KEGGibas:BUsg456.
PATRICi21247766. VBIBucAph100086_0482.

Phylogenomic databases

eggNOGiCOG1622.
KOiK02297.
OMAiKYAMADM.
OrthoDBiEOG6PS5TJ.

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-480-MONOMER.

Family and domain databases

Gene3Di1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProiIPR010514. COX_ARM.
IPR008972. Cupredoxin.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
IPR006333. Cyt_o_ubiquinol_oxidase_su2.
[Graphical view]
PfamiPF00116. COX2. 1 hit.
PF06481. COX_ARM. 1 hit.
[Graphical view]
PIRSFiPIRSF000292. Ubi_od_II. 1 hit.
SUPFAMiSSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
TIGRFAMsiTIGR01433. CyoA. 1 hit.
PROSITEiPS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiCYOA_BUCAP
AccessioniPrimary (citable) accession number: Q8K993
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: July 22, 2015
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.