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Q8K993

- CYOA_BUCAP

UniProt

Q8K993 - CYOA_BUCAP

Protein

Cytochrome bo(3) ubiquinol oxidase subunit 2

Gene

cyoA

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Cytochrome bo3 ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron By similarity.By similarity

    GO - Molecular functioni

    1. copper ion binding Source: InterPro
    2. cytochrome bo3 ubiquinol oxidase activity Source: InterPro
    3. cytochrome-c oxidase activity Source: InterPro
    4. cytochrome o ubiquinol oxidase activity Source: InterPro

    GO - Biological processi

    1. electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Respiratory chain, Transport

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-480-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome bo(3) ubiquinol oxidase subunit 2
    Alternative name(s):
    Cytochrome o ubiquinol oxidase subunit 2
    Short name:
    Cytochrome o subunit 2
    Oxidase bo(3) subunit 2
    Ubiquinol oxidase polypeptide II
    Ubiquinol oxidase subunit 2
    Gene namesi
    Name:cyoA
    Ordered Locus Names:BUsg_456
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    Subcellular locationi

    Cell membrane By similarity; Multi-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    3. respiratory chain Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2424Sequence AnalysisAdd
    BLAST
    Chaini25 – 290266Cytochrome bo(3) ubiquinol oxidase subunit 2PRO_0000006073Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Lipidationi25 – 251N-palmitoyl cysteineSequence Analysis
    Lipidationi25 – 251S-diacylglycerol cysteineSequence Analysis

    Keywords - PTMi

    Lipoprotein, Palmitate

    Interactioni

    Subunit structurei

    Heterooctamer of two A chains, two B chains, two C chains and two D chains.By similarity

    Protein-protein interaction databases

    STRINGi198804.BUsg456.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K993.
    SMRiQ8K993. Positions 125-281.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini25 – 4218ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini64 – 8724CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini109 – 290182ExtracellularSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei43 – 6321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei88 – 10821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1622.
    KOiK02297.
    OMAiKIEAVVW.
    OrthoDBiEOG6PS5TJ.

    Family and domain databases

    Gene3Di1.10.287.90. 1 hit.
    2.60.40.420. 1 hit.
    InterProiIPR012141. Bo-type_Ubol_Oxase_su_II.
    IPR010514. COX_ARM.
    IPR008972. Cupredoxin.
    IPR002429. Cyt_c_oxidase_su2_C.
    IPR011759. Cyt_c_oxidase_su2_TM_dom.
    IPR006333. Cyt_o_ubiquinol_oxidase_su2.
    [Graphical view]
    PfamiPF00116. COX2. 1 hit.
    PF06481. COX_ARM. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000292. Ubi_od_II. 1 hit.
    SUPFAMiSSF49503. SSF49503. 1 hit.
    SSF81464. SSF81464. 1 hit.
    TIGRFAMsiTIGR01433. CyoA. 1 hit.
    PROSITEiPS50857. COX2_CUA. 1 hit.
    PS50999. COX2_TM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8K993-1 [UniParc]FASTAAdd to Basket

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    MISINFNNFF KTLLLILIAF TLHGCDSILF NPHGIIAIQE CSILLISFLI    50
    MLFVIIPVIF MTIYFSVKYR ASNINAKYKP DWCDSKKIEI IVWTIPISII 100
    LFLAFVTWNY SHILDPKKSI ISKYKPIKID VVSLDWRWLF IYPEYHIATI 150
    NEIMFPINRS IIFHITSNSV MNSFFIPSLG SQIYAMPGMM TTLNLMSNSP 200
    GKYKGISSNY SGKGFSNMKF TAISVLNIKD FENWIKKAQQ SPKKLNKMSI 250
    FNIISLPNEN HFIEYFSDVK KNLFYEIINQ TYSKNKVFKH 290
    Length:290
    Mass (Da):33,730
    Last modified:October 1, 2002 - v1
    Checksum:i3D80A02A84732963
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67999.1.
    RefSeqiNP_660788.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM67999; AAM67999; BUsg_456.
    GeneIDi1005709.
    KEGGibas:BUsg456.
    PATRICi21247766. VBIBucAph100086_0482.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67999.1 .
    RefSeqi NP_660788.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali Q8K993.
    SMRi Q8K993. Positions 125-281.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg456.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM67999 ; AAM67999 ; BUsg_456 .
    GeneIDi 1005709.
    KEGGi bas:BUsg456.
    PATRICi 21247766. VBIBucAph100086_0482.

    Phylogenomic databases

    eggNOGi COG1622.
    KOi K02297.
    OMAi KIEAVVW.
    OrthoDBi EOG6PS5TJ.

    Enzyme and pathway databases

    BioCyci BAPH198804:GHMG-480-MONOMER.

    Family and domain databases

    Gene3Di 1.10.287.90. 1 hit.
    2.60.40.420. 1 hit.
    InterProi IPR012141. Bo-type_Ubol_Oxase_su_II.
    IPR010514. COX_ARM.
    IPR008972. Cupredoxin.
    IPR002429. Cyt_c_oxidase_su2_C.
    IPR011759. Cyt_c_oxidase_su2_TM_dom.
    IPR006333. Cyt_o_ubiquinol_oxidase_su2.
    [Graphical view ]
    Pfami PF00116. COX2. 1 hit.
    PF06481. COX_ARM. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000292. Ubi_od_II. 1 hit.
    SUPFAMi SSF49503. SSF49503. 1 hit.
    SSF81464. SSF81464. 1 hit.
    TIGRFAMsi TIGR01433. CyoA. 1 hit.
    PROSITEi PS50857. COX2_CUA. 1 hit.
    PS50999. COX2_TM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.

    Entry informationi

    Entry nameiCYOA_BUCAP
    AccessioniPrimary (citable) accession number: Q8K993
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3