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Protein

Cytochrome bo(3) ubiquinol oxidase subunit 2

Gene

cyoA

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochrome bo3 ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity).By similarity

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

BioCyciBAPH198804:G1FZU-481-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome bo(3) ubiquinol oxidase subunit 2
Alternative name(s):
Cytochrome o ubiquinol oxidase subunit 2
Short name:
Cytochrome o subunit 2
Oxidase bo(3) subunit 2
Ubiquinol oxidase polypeptide II
Ubiquinol oxidase subunit 2
Gene namesi
Name:cyoA
Ordered Locus Names:BUsg_456
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000000416 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini25 – 42ExtracellularSequence analysisAdd BLAST18
Transmembranei43 – 63HelicalSequence analysisAdd BLAST21
Topological domaini64 – 87CytoplasmicSequence analysisAdd BLAST24
Transmembranei88 – 108HelicalSequence analysisAdd BLAST21
Topological domaini109 – 290ExtracellularSequence analysisAdd BLAST182

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000000607325 – 290Cytochrome bo(3) ubiquinol oxidase subunit 2Add BLAST266

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi25N-palmitoyl cysteineSequence analysis1
Lipidationi25S-diacylglycerol cysteineSequence analysis1

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Subunit structurei

Heterooctamer of two A chains, two B chains, two C chains and two D chains.By similarity

Protein-protein interaction databases

STRINGi198804.BUsg456

Structurei

3D structure databases

ProteinModelPortaliQ8K993
SMRiQ8K993
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E2S Bacteria
COG1622 LUCA
KOiK02297
OMAiFARPTIN
OrthoDBiPOG091H0GRX

Family and domain databases

CDDicd04212 CuRO_UO_II, 1 hit
Gene3Di1.10.287.90, 1 hit
2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR002429 CcO_II-like_C
IPR010514 COX_ARM
IPR008972 Cupredoxin
IPR034227 CuRO_UO_II
IPR011759 Cyt_c_oxidase_su2_TM_dom
IPR036257 Cyt_c_oxidase_su2_TM_sf
IPR006333 Cyt_o_ubiquinol_oxidase_su2
PfamiView protein in Pfam
PF00116 COX2, 1 hit
PF06481 COX_ARM, 1 hit
PIRSFiPIRSF000292 Ubi_od_II, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
SSF81464 SSF81464, 1 hit
TIGRFAMsiTIGR01433 CyoA, 1 hit
PROSITEiView protein in PROSITE
PS50857 COX2_CUA, 1 hit
PS50999 COX2_TM, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8K993-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISINFNNFF KTLLLILIAF TLHGCDSILF NPHGIIAIQE CSILLISFLI
60 70 80 90 100
MLFVIIPVIF MTIYFSVKYR ASNINAKYKP DWCDSKKIEI IVWTIPISII
110 120 130 140 150
LFLAFVTWNY SHILDPKKSI ISKYKPIKID VVSLDWRWLF IYPEYHIATI
160 170 180 190 200
NEIMFPINRS IIFHITSNSV MNSFFIPSLG SQIYAMPGMM TTLNLMSNSP
210 220 230 240 250
GKYKGISSNY SGKGFSNMKF TAISVLNIKD FENWIKKAQQ SPKKLNKMSI
260 270 280 290
FNIISLPNEN HFIEYFSDVK KNLFYEIINQ TYSKNKVFKH
Length:290
Mass (Da):33,730
Last modified:October 1, 2002 - v1
Checksum:i3D80A02A84732963
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA Translation: AAM67999.1
RefSeqiWP_011053966.1, NC_004061.1

Genome annotation databases

EnsemblBacteriaiAAM67999; AAM67999; BUsg_456
KEGGibas:BUsg_456

Similar proteinsi

Entry informationi

Entry nameiCYOA_BUCAP
AccessioniPrimary (citable) accession number: Q8K993
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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