Q8K955 (RL22_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L22

Gene names

Name:	rplV
Ordered Locus Names:	BUsg_500

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	110 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity. HAMAP-Rule MF_01331 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome By similarity. HAMAP-Rule MF_01331
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Sequence similarities	Belongs to the ribosomal protein L22P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 110	110	50S ribosomal protein L22 HAMAP-Rule MF_01331		PRO_0000125131

Sequences

	Sequence		Length	Mass (Da)
	Q8K955 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: C7603CEA79B03341	FASTA	110	12,427
	10 20 30 40 50 60 METLAQHRQA RCSAQKIRLI ADLIRGKKVP KALNILNFNN KKAAILVKKV LESALANAEH 70 80 90 100 110 NDGLDVDQLR IKNIFVDEGS TMKRMMPRAK GRADRILKRT SHITVIVSDR

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013218 Genomic DNA. Translation: AAM68043.1.
RefSeq	NP_660832.1. NC_004061.1.
3D structure databases
ProteinModelPortal	Q8K955.
SMR	Q8K955. Positions 1-110.
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg500.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM68043; AAM68043; BUsg_500.
GeneID	1005669.
KEGG	bas:BUsg500.
PATRIC	21247864. VBIBucAph100086_0527.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0091.
KO	K02890.
OMA	ASRINKR.
ProtClustDB	PRK00565.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-545-MONOMER.
Family and domain databases
Gene3D	3.90.470.10. 1 hit.
HAMAP	MF_01331_B. Ribosomal_L22_B.
InterPro	IPR001063. Ribosomal_L22. IPR018260. Ribosomal_L22/L17_CS. IPR005727. Ribosomal_L22_bac/chlpt-type. [Graphical view]
PANTHER	PTHR13501. PTHR13501. 1 hit.
Pfam	PF00237. Ribosomal_L22. 1 hit. [Graphical view]
SUPFAM	SSF54843. Ribosomal_L22. 1 hit.
TIGRFAMs	TIGR01044. rplV_bact. 1 hit.
PROSITE	PS00464. RIBOSOMAL_L22. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL22_BUCAP

Accession

Primary (citable) accession number: Q8K955

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program