Q8K953 (RL2_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L2

Gene names

Name:	rplB
Ordered Locus Names:	BUsg_502

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	273 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome By similarity. HAMAP-Rule MF_01320
Subunit structure	Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome By similarity.
Sequence similarities	Belongs to the ribosomal protein L2P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 273	273	50S ribosomal protein L2 HAMAP-Rule MF_01320		PRO_0000129540

Sequences

	Sequence		Length	Mass (Da)
	Q8K953 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 8DAF3CD211793412	FASTA	273	30,444
	10 20 30 40 50 60 MAIVKCKPTS PGRRHVIKVV NKELYKGKPY SLLLSKKSKT GGRNNNGRIT TRHIGGGHKR 70 80 90 100 110 120 IYRIIDFKRN KDNITASIER FEYDPNRSSN IALILYKDGK RNYILAPKNL KVGDTVISGE 130 140 150 160 170 180 NVPIKIGNSL PIKNIPVGSF IHNVEMRPGK GGQIARSAGS YVQLVACDKE YATLRLRSGE 190 200 210 220 230 240 MRKTESNCRA TIGEVGNSEH MLKVLGKAGA SRWIGIRPTV RGTAMNPVDH PHGGGEGRNF 250 260 270 GKHPVTPWGL QTKGKKTRKN KRTEKFILRH RHK

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013218 Genomic DNA. Translation: AAM68045.1.
RefSeq	NP_660834.1. NC_004061.1.
3D structure databases
ProteinModelPortal	Q8K953.
SMR	Q8K953. Positions 2-271.
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg502.
Proteomic databases
PRIDE	Q8K953.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM68045; AAM68045; BUsg_502.
GeneID	1005667.
KEGG	bas:BUsg502.
PATRIC	21247868. VBIBucAph100086_0529.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0090.
KO	K02886.
OMA	LVRQECM.
ProtClustDB	PRK09374.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-530-MONOMER.
Family and domain databases
Gene3D	2.30.30.30. 1 hit. 2.40.50.140. 1 hit. 4.10.950.10. 1 hit.
HAMAP	MF_01320_B. Ribosomal_L2_B.
InterPro	IPR012340. NA-bd_OB-fold. IPR022666. Rbsml_prot_L2_RNA-bd_dom. IPR014722. Rib_L2_dom2. IPR002171. Ribosomal_L2. IPR005880. Ribosomal_L2_bac/org-type. IPR022669. Ribosomal_L2_C. IPR022671. Ribosomal_L2_CS. IPR014726. Ribosomal_L2_dom3. IPR008991. Translation_prot_SH3-like. [Graphical view]
PANTHER	PTHR13691. PTHR13691. 1 hit. PTHR13691:SF5. PTHR13691:SF5. 1 hit.
Pfam	PF00181. Ribosomal_L2. 1 hit. PF03947. Ribosomal_L2_C. 1 hit. [Graphical view]
PIRSF	PIRSF002158. Ribosomal_L2. 1 hit.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF50104. Transl_SH3_like. 1 hit.
TIGRFAMs	TIGR01171. rplB_bact. 1 hit.
PROSITE	PS00467. RIBOSOMAL_L2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL2_BUCAP

Accession

Primary (citable) accession number: Q8K953

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	May 29, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program