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Protein

50S ribosomal protein L2

Gene

rplB

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciBAPH198804:G1FZU-532-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L2UniRule annotation
Gene namesi
Name:rplBUniRule annotation
Ordered Locus Names:BUsg_502
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000000416 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001295401 – 27350S ribosomal protein L2Add BLAST273

Proteomic databases

PRIDEiQ8K953

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Protein-protein interaction databases

STRINGi198804.BUsg502

Structurei

3D structure databases

ProteinModelPortaliQ8K953
SMRiQ8K953
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL2 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFD Bacteria
COG0090 LUCA
KOiK02886
OMAiHGYIKGV
OrthoDBiPOG091H01QE

Family and domain databases

Gene3Di2.30.30.30, 1 hit
4.10.950.10, 1 hit
HAMAPiMF_01320_B Ribosomal_L2_B, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR022666 Rbsml_prot_L2_RNA-bd_dom
IPR014722 Rib_L2_dom2
IPR002171 Ribosomal_L2
IPR005880 Ribosomal_L2_bac/org-type
IPR022669 Ribosomal_L2_C
IPR022671 Ribosomal_L2_CS
IPR014726 Ribosomal_L2_dom3
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR13691 PTHR13691, 1 hit
PfamiView protein in Pfam
PF00181 Ribosomal_L2, 1 hit
PF03947 Ribosomal_L2_C, 1 hit
PIRSFiPIRSF002158 Ribosomal_L2, 1 hit
SMARTiView protein in SMART
SM01383 Ribosomal_L2, 1 hit
SM01382 Ribosomal_L2_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR01171 rplB_bact, 1 hit
PROSITEiView protein in PROSITE
PS00467 RIBOSOMAL_L2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8K953-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIVKCKPTS PGRRHVIKVV NKELYKGKPY SLLLSKKSKT GGRNNNGRIT
60 70 80 90 100
TRHIGGGHKR IYRIIDFKRN KDNITASIER FEYDPNRSSN IALILYKDGK
110 120 130 140 150
RNYILAPKNL KVGDTVISGE NVPIKIGNSL PIKNIPVGSF IHNVEMRPGK
160 170 180 190 200
GGQIARSAGS YVQLVACDKE YATLRLRSGE MRKTESNCRA TIGEVGNSEH
210 220 230 240 250
MLKVLGKAGA SRWIGIRPTV RGTAMNPVDH PHGGGEGRNF GKHPVTPWGL
260 270
QTKGKKTRKN KRTEKFILRH RHK
Length:273
Mass (Da):30,444
Last modified:October 1, 2002 - v1
Checksum:i8DAF3CD211793412
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA Translation: AAM68045.1
RefSeqiWP_011054011.1, NC_004061.1

Genome annotation databases

EnsemblBacteriaiAAM68045; AAM68045; BUsg_502
KEGGibas:BUsg_502

Similar proteinsi

Entry informationi

Entry nameiRL2_BUCAP
AccessioniPrimary (citable) accession number: Q8K953
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: May 23, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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