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Q8K945 (TUSC_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein TusC
Alternative name(s):
tRNA 2-thiouridine synthesizing protein C
Gene names
Name:tusC
Ordered Locus Names:BUsg_512
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length119 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions By similarity. HAMAP-Rule MF_00389

Subunit structure

Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00389.

Sequence similarities

Belongs to the DsrF/TusC family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 119119Protein TusC HAMAP-Rule MF_00389
PRO_0000214881

Sequences

Sequence LengthMass (Da)Tools
Q8K945 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 6EE924AD44058CC0

FASTA11913,610
        10         20         30         40         50         60 
MEKIAFVFSH APHGTSFGKE GLDVILGVSS IIKKISLFFI GDGVLQILKH SKSENILARN 

        70         80         90        100        110 
YTSSFRILSI YDIKNFYCCK SSLIDRGLYS HNQFILKVNI LNSYFFRIKL DDHDAIINF 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM68055.1.
RefSeqNP_660844.2. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K945.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg512.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM68055; AAM68055; BUsg_512.
GeneID1005659.
KEGGbas:BUsg512.
PATRIC21247888. VBIBucAph100086_0539.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2923.
KOK07236.
OMAEKLYVDR.
OrthoDBEOG6RVFZF.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-540-MONOMER.

Family and domain databases

Gene3D3.40.1260.10. 1 hit.
HAMAPMF_00389. Thiourid_synth_C.
InterProIPR027396. DsrEFH-like.
IPR003787. Sulphur_relay_DrsE/F-like.
IPR017462. Sulphur_relay_TusC/DsrF.
[Graphical view]
PfamPF02635. DrsE. 1 hit.
[Graphical view]
SUPFAMSSF75169. SSF75169. 1 hit.
TIGRFAMsTIGR03010. sulf_tusC_dsrF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTUSC_BUCAP
AccessionPrimary (citable) accession number: Q8K945
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names