Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8K935

- RF3_BUCAP

UniProt

Q8K935 - RF3_BUCAP

Protein

Peptide chain release factor 3

Gene

prfC

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi20 – 278GTPUniRule annotation
    Nucleotide bindingi88 – 925GTPUniRule annotation
    Nucleotide bindingi142 – 1454GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation release factor activity, codon specific Source: UniProtKB-HAMAP

    GO - Biological processi

    1. regulation of translational termination Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-552-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptide chain release factor 3UniRule annotation
    Short name:
    RF-3UniRule annotation
    Gene namesi
    Name:prfCUniRule annotation
    Ordered Locus Names:BUsg_523
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 529529Peptide chain release factor 3PRO_0000210934Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi198804.BUsg523.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K935.
    SMRiQ8K935. Positions 9-529.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini11 – 280270tr-type GAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG4108.
    KOiK02837.
    OMAiFHKTREH.
    OrthoDBiEOG6677Q1.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00072. Rel_fac_3.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR009022. EFG_III-V.
    IPR027417. P-loop_NTPase.
    IPR004548. PrfC.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF54980. SSF54980. 1 hit.
    TIGRFAMsiTIGR00503. prfC. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8K935-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFNINHQLEL SKRRTFAIIS HPDAGKTTVT EKMLLLGKVI RTSGTIKARG    50
    NGKYAKSDWM NIEKKRGISI TTSVMQFTYK NTLMNLLDTP GHEDFSEDTY 100
    RILTAVDCCL LIIDAAKGIE DRTKKLINVS RLHNTPVITF INKLDRDSRE 150
    AIEILDEIEK ELSLDCIPIT WPISCGKNFK GICHIHDKIV NLYQKNIVKK 200
    INFNSFSSFL NEHSLKEYLG ADLYTQLHEE LKLAAYVYPK FSKKKFLKGD 250
    ITPVLFGSAL NNFGIDHILE SLIKWAPSPI YRVTKTRKVE PEEKKFTGFV 300
    FKIQANMDLK HRDRIAFMRI VSGKYKKGIK LRHVRMKKDI IVSDAFSFLA 350
    GDRFSIEHAY PGDVIGIHNH GTIKIGDTFT EGEEIKFVGI PSFAPEVFRR 400
    IFLKNPLQQK KLKKGLSQLS EEGAIQVFRP MINNSLILGA IGILQFDVVI 450
    ERLKIEYKID AIYERVNISL ARWIRSKNKK IISDFINKNK SYLALDISNQ 500
    LIYLAPNKAN LAVIKNIYNN IFFEKTREQ 529
    Length:529
    Mass (Da):60,738
    Last modified:October 1, 2002 - v1
    Checksum:iB13984DD4305833B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM68066.1.
    RefSeqiNP_660855.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM68066; AAM68066; BUsg_523.
    GeneIDi1005652.
    KEGGibas:BUsg523.
    PATRICi21247912. VBIBucAph100086_0550.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM68066.1 .
    RefSeqi NP_660855.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali Q8K935.
    SMRi Q8K935. Positions 9-529.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg523.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM68066 ; AAM68066 ; BUsg_523 .
    GeneIDi 1005652.
    KEGGi bas:BUsg523.
    PATRICi 21247912. VBIBucAph100086_0550.

    Phylogenomic databases

    eggNOGi COG4108.
    KOi K02837.
    OMAi FHKTREH.
    OrthoDBi EOG6677Q1.

    Enzyme and pathway databases

    BioCyci BAPH198804:GHMG-552-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00072. Rel_fac_3.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR009022. EFG_III-V.
    IPR027417. P-loop_NTPase.
    IPR004548. PrfC.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF54980. SSF54980. 1 hit.
    TIGRFAMsi TIGR00503. prfC. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.

    Entry informationi

    Entry nameiRF3_BUCAP
    AccessioniPrimary (citable) accession number: Q8K935
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3