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Protein

Oxygen-independent coproporphyrinogen-III oxidase-like protein BUsg_532

Gene

BUsg_532

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the biosynthesis of porphyrin-containing compound.By similarity

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei10 – 101S-adenosyl-L-methionine 1By similarity
Metal bindingi16 – 161Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis
Metal bindingi20 – 201Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis
Binding sitei22 – 221S-adenosyl-L-methionine 2; via carbonyl oxygenBy similarity
Metal bindingi23 – 231Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis
Binding sitei66 – 661S-adenosyl-L-methionine 1; via amide nitrogen and carbonyl oxygenBy similarity
Binding sitei99 – 991S-adenosyl-L-methionine 1By similarity
Binding sitei126 – 1261S-adenosyl-L-methionine 2By similarity
Binding sitei138 – 1381S-adenosyl-L-methionine 2By similarity
Binding sitei162 – 1621S-adenosyl-L-methionine 2By similarity

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB
  2. coproporphyrinogen oxidase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. porphyrin-containing compound biosynthetic process Source: UniProtKB
  2. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Porphyrin biosynthesis

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-561-MONOMER.
UniPathwayiUPA00251.

Names & Taxonomyi

Protein namesi
Recommended name:
Oxygen-independent coproporphyrinogen-III oxidase-like protein BUsg_532 (EC:1.3.99.-)
Gene namesi
Ordered Locus Names:BUsg_532
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 376376Oxygen-independent coproporphyrinogen-III oxidase-like protein BUsg_532PRO_0000109959Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg532.

Structurei

3D structure databases

ProteinModelPortaliQ8K928.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni67 – 682S-adenosyl-L-methionine 2 bindingBy similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0635.
KOiK02495.
OMAiRTAKTRH.
OrthoDBiEOG683S9D.

Family and domain databases

Gene3Di3.80.30.20. 1 hit.
InterProiIPR004559. Coprogen_oxidase_HemN-rel.
IPR006638. Elp3/MiaB/NifB.
IPR007197. rSAM.
IPR023404. rSAM_horseshoe.
[Graphical view]
PfamiPF04055. Radical_SAM. 1 hit.
[Graphical view]
SMARTiSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00539. hemN_rel. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K928-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKLPPISLY IHIPWCIKKC GYCDFYSYVN KSFIPEKEYI DHLLKDLEKD
60 70 80 90 100
LSLIKEREIN SIFIGGGTPS LLKSSSIKKM MREIKKRINI SNTAEITIEA
110 120 130 140 150
NPTTLEYKRF FNYKKSGINR FSIGVQTFNS DLLKKIERTY NKREAILAVE
160 170 180 190 200
EIKKINKNFN LDIMYGLPNQ SLKDVLLDLQ YAVKYNPTHI SWYQLTLEPN
210 220 230 240 250
TPFYVKKLNL PNENNIFKML VEGEKFLKQS GYKKYEISSY AKLNYECQHN
260 270 280 290 300
LNYWNFGDYI GIGCSAHGKI TQINGDIIRT IKNKNINDFM NGKYLKHKNF
310 320 330 340 350
VLKKDKPFEY FMNIFRLYKP VLKRQFEERT NINQNYIKEK IKKAIEKGYL
360 370
KNKIDFWDTT KKGKMFLNSL LKIFLD
Length:376
Mass (Da):44,581
Last modified:October 1, 2002 - v1
Checksum:i4808E9524404C0F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM68073.1.
RefSeqiNP_660862.1. NC_004061.1.
WP_011054039.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM68073; AAM68073; BUsg_532.
KEGGibas:BUsg532.
PATRICi21247936. VBIBucAph100086_0562.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM68073.1.
RefSeqiNP_660862.1. NC_004061.1.
WP_011054039.1. NC_004061.1.

3D structure databases

ProteinModelPortaliQ8K928.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198804.BUsg532.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM68073; AAM68073; BUsg_532.
KEGGibas:BUsg532.
PATRICi21247936. VBIBucAph100086_0562.

Phylogenomic databases

eggNOGiCOG0635.
KOiK02495.
OMAiRTAKTRH.
OrthoDBiEOG683S9D.

Enzyme and pathway databases

UniPathwayiUPA00251.
BioCyciBAPH198804:GHMG-561-MONOMER.

Family and domain databases

Gene3Di3.80.30.20. 1 hit.
InterProiIPR004559. Coprogen_oxidase_HemN-rel.
IPR006638. Elp3/MiaB/NifB.
IPR007197. rSAM.
IPR023404. rSAM_horseshoe.
[Graphical view]
PfamiPF04055. Radical_SAM. 1 hit.
[Graphical view]
SMARTiSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00539. hemN_rel. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiY532_BUCAP
AccessioniPrimary (citable) accession number: Q8K928
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: April 29, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.