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Q8K915 (HFLC_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein HflC
Gene names
Name:hflC
Ordered Locus Names:BUsg_547
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

HflC and HflK could regulate a protease By similarity.

Subunit structure

HflC and HflK may interact to form a multimeric complex By similarity.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the band 7/mec-2 family. HflC subfamily.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processregulation of peptidase activity

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Protein HflC
PRO_0000094071

Regions

Transmembrane3 – 2321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q8K915 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 0ED2B7509FF43F34

FASTA30735,444
        10         20         30         40         50         60 
MNKIVICILS FFLLIFSSSF FIVKEGERGI ILQFGKVLRN NKQKTLVYTP GLHFKIPFFE 

        70         80         90        100        110        120 
NVKILDSRIH TMDNQADRFV TKEKKDLIVD SYIKWRISDF SRYYLATGGG DFFQAEVLLK 

       130        140        150        160        170        180 
RKFSDRLRSE IGRLNVKEIV TDSRGRLTTD VLYSLNKGTI NLDSTSLINV NSMNALGIEV 

       190        200        210        220        230        240 
VDVRIKQINL PLEVSDAIYN RMRAERESVA RSQRSQGQEK AEKLRATADY RVSLILAEAQ 

       250        260        270        280        290        300 
KKALMIKGQG EAEVAKLFLE NFGQESSFYF FIRSLHAYEN SFKNSNNIML INSDNEFFKY 


MNTEIKN 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM68086.1.
RefSeqNP_660875.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K915.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg547.

Protein family/group databases

MEROPSI87.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM68086; AAM68086; BUsg_547.
GeneID1005822.
KEGGbas:BUsg547.
PATRIC21247972. VBIBucAph100086_0578.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0330.
KOK04087.
OMAPQFAQFY.
OrthoDBEOG6B8XHM.
ProtClustDBPRK11029.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-578-MONOMER.

Family and domain databases

InterProIPR001107. Band_7.
IPR010200. HflC.
IPR001972. Stomatin_fam.
[Graphical view]
PANTHERPTHR10264. PTHR10264. 1 hit.
PTHR10264:SF52. PTHR10264:SF52. 1 hit.
PfamPF01145. Band_7. 1 hit.
[Graphical view]
PIRSFPIRSF005651. HflC. 1 hit.
SMARTSM00244. PHB. 1 hit.
[Graphical view]
TIGRFAMsTIGR01932. hflC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameHFLC_BUCAP
AccessionPrimary (citable) accession number: Q8K915
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names