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Protein

Protein HflC

Gene

hflC

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

HflC and HflK could regulate a protease.By similarity

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-578-MONOMER.

Protein family/group databases

MEROPSiI87.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HflC
Gene namesi
Name:hflC
Ordered Locus Names:BUsg_547
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Protein HflCPRO_0000094071Add
BLAST

Interactioni

Subunit structurei

HflC and HflK may interact to form a multimeric complex.By similarity

Protein-protein interaction databases

STRINGi198804.BUsg547.

Structurei

3D structure databases

ProteinModelPortaliQ8K915.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the band 7/mec-2 family. HflC subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0330.
KOiK04087.
OMAiDPQFAQF.
OrthoDBiEOG6B8XHM.

Family and domain databases

InterProiIPR001107. Band_7.
IPR010200. HflC.
IPR001972. Stomatin_fam.
[Graphical view]
PANTHERiPTHR10264. PTHR10264. 1 hit.
PTHR10264:SF52. PTHR10264:SF52. 1 hit.
PfamiPF01145. Band_7. 1 hit.
[Graphical view]
PIRSFiPIRSF005651. HflC. 1 hit.
SMARTiSM00244. PHB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01932. hflC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K915-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKIVICILS FFLLIFSSSF FIVKEGERGI ILQFGKVLRN NKQKTLVYTP
60 70 80 90 100
GLHFKIPFFE NVKILDSRIH TMDNQADRFV TKEKKDLIVD SYIKWRISDF
110 120 130 140 150
SRYYLATGGG DFFQAEVLLK RKFSDRLRSE IGRLNVKEIV TDSRGRLTTD
160 170 180 190 200
VLYSLNKGTI NLDSTSLINV NSMNALGIEV VDVRIKQINL PLEVSDAIYN
210 220 230 240 250
RMRAERESVA RSQRSQGQEK AEKLRATADY RVSLILAEAQ KKALMIKGQG
260 270 280 290 300
EAEVAKLFLE NFGQESSFYF FIRSLHAYEN SFKNSNNIML INSDNEFFKY

MNTEIKN
Length:307
Mass (Da):35,444
Last modified:October 1, 2002 - v1
Checksum:i0ED2B7509FF43F34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM68086.1.
RefSeqiNP_660875.1. NC_004061.1.
WP_011054052.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM68086; AAM68086; BUsg_547.
KEGGibas:BUsg547.
PATRICi21247972. VBIBucAph100086_0578.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM68086.1.
RefSeqiNP_660875.1. NC_004061.1.
WP_011054052.1. NC_004061.1.

3D structure databases

ProteinModelPortaliQ8K915.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198804.BUsg547.

Protein family/group databases

MEROPSiI87.001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM68086; AAM68086; BUsg_547.
KEGGibas:BUsg547.
PATRICi21247972. VBIBucAph100086_0578.

Phylogenomic databases

eggNOGiCOG0330.
KOiK04087.
OMAiDPQFAQF.
OrthoDBiEOG6B8XHM.

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-578-MONOMER.

Family and domain databases

InterProiIPR001107. Band_7.
IPR010200. HflC.
IPR001972. Stomatin_fam.
[Graphical view]
PANTHERiPTHR10264. PTHR10264. 1 hit.
PTHR10264:SF52. PTHR10264:SF52. 1 hit.
PfamiPF01145. Band_7. 1 hit.
[Graphical view]
PIRSFiPIRSF005651. HflC. 1 hit.
SMARTiSM00244. PHB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01932. hflC. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiHFLC_BUCAP
AccessioniPrimary (citable) accession number: Q8K915
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: May 27, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.