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Q8K910 (G6PI_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:BUsg_553
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length555 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 555555Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180613

Sites

Active site3551Proton donor By similarity
Active site3861 By similarity
Active site5141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8K910 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 5472E184C3D72A30

FASTA55563,957
        10         20         30         40         50         60 
MKNINLIETK SWKDLKNHFK EVKNIHLKDL FLSDFNRFKK FSIFFENEIL IDFSKNRITE 

        70         80         90        100        110        120 
KTLILLLNLA KEMNVKSAIK LMFSGSKINQ TENRSVLHIA LRNRSNFPIL LNNSDIMSEV 

       130        140        150        160        170        180 
NDVLKKMKNF SELVIDGTWK GYSGKSISDV VNIGIGGSDL GPYMVTEALR PYKNHLNIHY 

       190        200        210        220        230        240 
VSNIDGTHLS EILKKINPET TIFLIASKTF TTDETITNAN SAKFWFLKHS KTKETLDKHF 

       250        260        270        280        290        300 
FALSANINNA VNFGINIKNI FQFWDWVGGR FSLWSSAGLS IVLSIGFNNF EKFLQGAHVM 

       310        320        330        340        350        360 
DNHFYHTEYD KNIPILLALI SIWYTNFFNS ETEAIFPYDQ YMHRFSAYFQ QSNMESNGKS 

       370        380        390        400        410        420 
IDKNGNKVCY QTGPIIWGEP GTNGQHAFFQ LIHQGTKLIP SDFIVPTVSH NNLNDHHLKL 

       430        440        450        460        470        480 
ISNFLAQTQV LAFGKSKNSF LKESTSFKKE EDEFNRILPF KICEGNKPTN SILLRKITPY 

       490        500        510        520        530        540 
TLGMLIALYE HKIFVQGHIL NIFSFDQWGV EIGKEVAQSI YKNINEKTKN SKSYDSSTQG 

       550 
LIDFYNFFKN KQNYL 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM68091.1.
RefSeqNP_660880.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K910.
SMRQ8K910. Positions 5-547.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg553.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM68091; AAM68091; BUsg_553.
GeneID1005724.
KEGGbas:BUsg553.
PATRIC21247986. VBIBucAph100086_0585.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-584-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_BUCAP
AccessionPrimary (citable) accession number: Q8K910
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names