Reviewed, UniProtKB/Swiss-Prot Q8K8H1 (Y292_STRP3)

Names and origin

Protein names

Recommended name:
    UPF0011 protein SpyM3_0292/SPs1565

Gene names

Ordered Locus Names:

SpyM3_0292, SPs1565

Organism

Streptococcus pyogenes serotype M3 [Complete proteome] [HAMAP]

Taxonomic identifier

301448 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the UPF0011 family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 287	287	UPF0011 protein SpyM3_0292/SPs1565		PRO_0000211955

Sequences

	Sequence		Length	Mass (Da)
	Q8K8H1-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 66A6F0E9FE114140	FASTA	287	31,866
	10 20 30 40 50 60 MQVQKSFKDK KTSGTLYLVP TPIGNLQDMT FRAVATLKEV DFICAEDTRN TGLLLKHFDI 70 80 90 100 110 120 ATKQISFHEH NAYEKIPDLI DLLISGRSLA QVSDAGMPSI SDPGHDLVKA AIDSDITVVA 130 140 150 160 170 180 LPGASAGITA LIASGLAPQP HVFYGFLPRK AGQQKAFFED KHHYPETQMF YESPYRIKDT 190 200 210 220 230 240 LTNMLACYGD RQVVLVRELT KLFEEYQRGS ISEILSYLEE TSLKGECLLI VAGAQVDSEV 250 260 270 280 ELTADVDLVS LVQKEIQAGA KPNQAIKTIA KAYQVNRQEL YQQFHDL

References

[1]

"Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence." Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D., Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S., Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M. Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002) [PubMed: 12122206] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-595 / MGAS315 / Serotype M3.

[2]

"Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution." Nakagawa I., Kurokawa K., Yamashita A., Nakata M., Tomiyasu Y., Okahashi N., Kawabata S., Yamazaki K., Shiba T., Yasunaga T., Hayashi H., Hattori M., Hamada S. Genome Res. 13:1042-1055(2003) [PubMed: 12799345] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SSI-1 / Serotype M3.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014074 Genomic DNA. Translation: AAM78899.1. BA000034 Genomic DNA. Translation: BAC64660.1.
RefSeq	NP_664096.1. NP_802827.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1008606. 1065221.
GenomeReviews	Gene locus SpyM3_0292 in contig AE014074_GR. Gene locus SPs1565 in contig BA000034_GR.
KEGG	spg:SpyM3_0292. sps:SPs1565.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8K8H1.
OMA	ASDRFCF
Enzyme and pathway databases
BioCyc	SPYO193567:SPS1565-MON. SPYO198466:SPYM3_0292-MON.
Family and domain databases
InterPro	IPR000878. 4pyrrol_Mease. IPR014777. 4pyrrole_Mease_sub1. IPR008189. UPF0011. IPR018063. UPF0011_CS. [Graphical view]
Gene3D	G3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
Pfam	PF00590. TP_methylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00096. UPF0011. 1 hit.
PROSITE	PS01296. UPF0011. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y292_STRP3

Accession

Primary (citable) accession number: Q8K8H1
Secondary accession number(s): Q79WD8

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	October 1, 2002
Last modified:	November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)