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Q8K7U5 (Q8K7U5_STRP3) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Branched-chain-amino-acid aminotransferase RuleBase RU004517
EC=2.6.1.42 RuleBase RU004517
Gene names
Name:bcaT EMBL AAM79233.1
Ordered Locus Names:SpyM3_0626
OrganismStreptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315) [Complete proteome] [HAMAP]
Taxonomic identifier198466 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate. RuleBase RU004517

L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate. RuleBase RU004517

L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate. RuleBase RU004517

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU004516

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4. RuleBase RU004519

Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4. RuleBase RU004519

Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4. RuleBase RU004519

Sequence similarities

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue1851N6-(pyridoxal phosphate)lysine By similarity PIRSR PIRSR006468-1

Sequences

Sequence LengthMass (Da)Tools
Q8K7U5 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 3FF1E92D59CB8F60

FASTA34137,222
        10         20         30         40         50         60 
MMTIAIDWDN LGFEYHKLPF RYISYYKNGQ WDKGQLTEDA TLHISESAPA LHYGQQAFEG 

        70         80         90        100        110        120 
LKAYRTKDGS IQLFRPDRNA VRLQATADRL LMPQVSTEQF IDAAKQVVKA NEDFVPPYGT 

       130        140        150        160        170        180 
GATLYLRPLL IGVGDIIGVK PAEEYIFTIF AMPVGNYFKG GLAPTNFIVS EAFDRAAPYG 

       190        200        210        220        230        240 
TGAAKVGGNY AGSLLPGKAA KSAGFSDVIY LDPATHTKIE EVGAANFFGI TANNEFVTPL 

       250        260        270        280        290        300 
SPSILPSITK YSLLQLAEER LGMTVIEGDV PINELDKFVE VGACGTAAVI SPIGGIQYKD 

       310        320        330        340 
NLHVFYSETE VGPVTRRLYD ELVGIQFGDI EAPEGWIVKV D

« Hide

References

[1]"Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence."
Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D., Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S., Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.
Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-595 / MGAS315.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014074 Genomic DNA. Translation: AAM79233.1.
RefSeqNP_664430.1. NC_004070.1.

3D structure databases

HSSPHSSP built from PDB template 1A3G based on UniProtKB P00510.
ProteinModelPortalQ8K7U5.
ModBaseSearch...

Protein-protein interaction databases

STRING193567.SPs1227.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM79233; AAM79233; SpyM3_0626.
GeneID1008940.
KEGGspg:SpyM3_0626.
PATRIC19735902. VBIStrPyo96585_0698.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000276704.
KOK00826.
OMASPIGGVQ.
ProtClustDBPRK13357.

Enzyme and pathway databases

UniPathwayUPA00047; UER00058.
UPA00048; UER00073.
UPA00049; UER00062.

Family and domain databases

InterProIPR001544. Aminotrans_IV.
IPR018300. Aminotrans_IV_CS.
IPR005786. B_amino_transII.
[Graphical view]
PANTHERPTHR11825. PTHR11825. 1 hit.
PTHR11825:SF2. PTHR11825:SF2. 1 hit.
PfamPF01063. Aminotran_4. 1 hit.
[Graphical view]
PIRSFPIRSF006468. BCAT1. 1 hit.
SUPFAMSSF56752. Aminotrans_IV. 1 hit.
TIGRFAMsTIGR01123. ilvE_II. 1 hit.
PROSITEPS00770. AA_TRANSFER_CLASS_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8K7U5_STRP3
AccessionPrimary (citable) accession number: Q8K7U5
Secondary accession number(s): Q79WX3
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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