Q8K7S1 (Q8K7S1_STRP3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Extracellular hyaluronate lyase EMBL AAM79272.1

Gene names

Name:	hylA EMBL AAM79272.1
Ordered Locus Names:	SpyM3_0665

Organism

Streptococcus pyogenes serotype M3 [Complete proteome] [HAMAP]

Taxonomic identifier

301448 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	807 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL AAM79272.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro carbon-oxygen lyase activity, acting on polysaccharides Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8K7S1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: A8187BEB44CF01A7	FASTA	807	92,581
	10 20 30 40 50 60 MNTYFCTHHK QLLLYSNLFL SFAMMGQGTA IYADTLTSNS EPNNTYFQTQ TLTTTDSEKK 70 80 90 100 110 120 VVQPQQKDYY TELLDQWNSI IAGNDAYDKT NPDMVTFHNK AEKDAQNIIK SYQGPDHENR 130 140 150 160 170 180 TYLWEHAKDY SASTNITKTY RNIEKIAKQI TNPESCYYQD SKAIAIVKDG MAFMYEHAYN 190 200 210 220 230 240 LNRENHQTTG KENKENWWVY EIGTPRAINN TLSLMYPYFT QEEILKYTAP IEKFVPDPTR 250 260 270 280 290 300 FRVRAANFSP FEASSGNLID MGRVKLISGI LRKDDLEISD TIKAIEKVFT LVDEGNGFYQ 310 320 330 340 350 360 DGSLIDHVVT NAQSPLYKKG IAYTGAYGNV LIDGLSQLIP IIQKTKSPIE ADKMATIYHW 370 380 390 400 410 420 INHSFFPIIV RGEMMDMTRG RSISRFNAQS HVAGIEALRA ILRIADMSEE PHRLALKTRI 430 440 450 460 470 480 KTLVTQGNAF YNVYDNLKTY HDIKLMKELL SDTSVPVQKL DSYVASFNSM DKLALYNNKH 490 500 510 520 530 540 DFAFGLSMFS NRTQNYEAMN NENLHGWFTS DGMFYLYNND LGHYSENYWA TVNPYRLPGT 550 560 570 580 590 600 TETEQKPLEG TPENIKTNYQ QVGMTSLSDD AFVASKKLNN TSALAAMTFT NWNKSLTLNK 610 620 630 640 650 660 GWFILGNKII FVGSNIKNQS SHKAYTTIEQ RKENQKHPYC SYVNNQPVDL NNQLVDFTNT 670 680 690 700 710 720 KSIFLESDDP AQNIGYYFFK PTTLSISKAL QTGKWQNIKA DDKSPEAIKE VSNTFITIMQ 730 740 750 760 770 780 NHTQDGDRYA YMMLPNMTRQ EFETYISKLD IDLLENNALN SHKIPHKRQR RLPHTGYQSS 790 800 SLEFLGGALV ASFNHITKPF RKKDLRI

References

[1]

"Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence." Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D., Liu M.Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S., Smith T.M., McCormick J.K., Leung D.Y., Schlievert P.M., Musser J.M. Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002) [PubMed: 12122206] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-595 / MGAS315 / Serotype M3.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014074 Genomic DNA. Translation: AAM79272.1.
RefSeq	NP_664469.1. NC_004070.1.
3D structure databases
HSSP	HSSP built from PDB template 1LXM based on UniProtKB Q53591.
ProteinModelPortal	Q8K7S1.
SMR	Q8K7S1. Positions 67-783.
ModBase	Search...
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000034989; EBSTRP00000033728; EBSTRG00000034989.
GeneID	1008979.
GenomeReviews	Gene locus SpyM3_0665 in contig AE014074_GR.
KEGG	spg:SpyM3_0665.
PATRIC	19735994. VBIStrPyo96585_0741.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027679.
HOGENOM	HBG698564.
OMA	TKTYRNI.
ProtClustDB	CLSK442844.
Enzyme and pathway databases
BioCyc	SPYO198466:SPYM3_0665-MONOMER.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR012970. Lyase_8_alpha_N. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
Pfam	PF02278. Lyase_8. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8K7S1_STRP3

Accession

Primary (citable) accession number: Q8K7S1

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)