Unreviewed, UniProtKB/TrEMBL Q8K571 (Q8K571_RAT)

Names and origin

Protein names

Submitted name:
    ADH-like protein EMBL AAM34269.1

Gene names

Name:

Adh1 RGD 2044

Organism

Rattus norvegicus (Rat) EMBL AAM34269.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Cofactor

Zinc By similarity. RuleBase RU000467V1

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU000467V1 Zinc RuleBase RU000467V1
Molecular function	Oxidoreductase RuleBase RU000467V1
Gene Ontology (GO)
Biological process	acetaldehyde biosynthetic process Inferred from direct assay. Source: RGD behavioral response to ethanol Inferred from electronic annotation. Source: Compara ethanol catabolic process Inferred from electronic annotation. Source: Compara ethanol oxidation Inferred from direct assay. Source: RGD oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to retinoic acid Inferred from electronic annotation. Source: Compara response to testosterone stimulus Inferred from electronic annotation. Source: Compara retinoic acid metabolic process Inferred from electronic annotation. Source: Compara retinol metabolic process Inferred from electronic annotation. Source: Compara
Cellular component	cytosol Inferred from direct assay. Source: RGD mitochondrion Inferred from electronic annotation. Source: Compara soluble fraction Inferred from direct assay. Source: RGD
Molecular function	NAD or NADH binding Inferred from direct assay. Source: RGD alcohol dehydrogenase (NAD) activity Inferred from direct assay. Source: RGD drug binding Inferred from physical interaction. Source: RGD ethanol binding Inferred from direct assay. Source: RGD protein homodimerization activity Inferred from electronic annotation. Source: Compara zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8K571-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 4B24FE255A771AA8	FASTA	376	39,717
	10 20 30 40 50 60 MSTAGKVIKC KAAVLWEPHK PFTIEDIEVA PPKAHEVRIK MVATGVCRSD DHAVSGSLFT 70 80 90 100 110 120 PLPAVLGHEG AGIVESIGEG VTCVKPGDKV IPLFSPQCGK CRICKHPESN LCCQTKNLTQ 130 140 150 160 170 180 PKGALLDGTS RFSCRGKPIH HFISTSTFSQ YTVVDDIAVA KIDAAAPLDK VCLIGCGFST 190 200 210 220 230 240 GYGSAVQVAK VTPGSTCAVF GLEGVGLSVV IGCKTAGAAK IIAVDINKDK FAKAKELGAT 250 260 270 280 290 300 DCINPQDYTK PIQEVLQEMT DGGVDFSFEV IGRLDTMTSA LLSCHSACGV SVIVGVPPSA 310 320 330 340 350 360 QSLSVNPMSL LLGRTWKGAI FGGFKSKDAV PKLVADFMAK KFPLEPLITH VLPFEKINEA 370 FDLLRAGKSI RTVLTF

References

[1]	"Cloning and analysis of up-regulated genes in rat liver." Li Y., Xu C., Zhang Y. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF508795 mRNA. Translation: AAM34269.1.
IPI	IPI00331983.
RefSeq	NP_062159.3.
UniGene	Rn.40222
3D structure databases
HSSP	HSSP built from PDB template 1HT0 based on UniProtKB P00326.
SMR	Q8K571. Positions 2-376.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8K571.
Genome annotation databases
Ensembl	ENSRNOT00000016346; ENSRNOP00000016346; ENSRNOG00000012464; Rattus norvegicus. [Genome view]
GeneID	24172.
KEGG	rno:24172.
Organism-specific databases
CTD	24172.
Phylogenomic databases
HOVERGEN	Q8K571.
InParanoid	Q8K571.
Gene expression databases
ArrayExpress	Q8K571.
Genevestigator	Q8K571.
Family and domain databases
InterPro	IPR013154. ADH_GroES-like. IPR002085. ADH_SF_Zn. IPR013149. ADH_Zn-bd. IPR002328. ADH_Zn_CS. IPR011032. GroES-like. IPR016040. NAD(P)-bd_dom. [Graphical view]
PANTHER	PTHR11695. ADH_Sf_Zn. 1 hit.
Pfam	PF08240. ADH_N. 1 hit. PF00107. ADH_zinc_N. 1 hit. [Graphical view]
PROSITE	PS00059. ADH_ZINC. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	602493.

Entry information

Entry name

Q8K571_RAT

Accession

Primary (citable) accession number: Q8K571

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	February 9, 2010
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)