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Q8K4Q1

- Q8K4Q1_MOUSE

UniProt

Q8K4Q1 - Q8K4Q1_MOUSE

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Protein
Submitted name:

Pax1 protein

Gene

Pax1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. bone morphogenesis Source: MGI
  2. CD4-positive, alpha-beta T cell differentiation Source: MGI
  3. CD8-positive, alpha-beta T cell differentiation Source: MGI
  4. cell proliferation Source: MGI
  5. organ morphogenesis Source: MGI
  6. parathyroid gland development Source: MGI
  7. pattern specification process Source: MGI
  8. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  9. regulation of transcription, DNA-templated Source: MGI
  10. skeletal system development Source: MGI
  11. somitogenesis Source: MGI
  12. thymus development Source: MGI
  13. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Pax1 proteinImported
Gene namesi
Name:Pax1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97485. Pax1.

Subcellular locationi

Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
  2. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiQ8K4Q1.
ExpressionAtlasiQ8K4Q1. baseline and differential.
GenevestigatoriQ8K4Q1.

Structurei

3D structure databases

ProteinModelPortaliQ8K4Q1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 paired domain.UniRule annotation
Contains paired domain.SAAS annotation

Keywords - Domaini

Paired boxUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG009115.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00292. PAX. 1 hit.
[Graphical view]
PRINTSiPR00027. PAIREDBOX.
SMARTiSM00351. PAX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8K4Q1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEQTYGEVNQ LGGVFVNGRP LPNAIRLRIV ELAQLGIRPC DISRQLRVSH
60 70 80 90 100
GCVSKILARY NETGSILPGA IGGSKPRVTT PNVVKHIRDY KQGDPGIFAW
110 120 130 140 150
EIRDRLLADG VCDKYNVPSV SSISRILRNK IGSLAQPGPY EASKQPPPQP
160 170 180 190 200
ALPYNHIYQY PYPSPVSPTG TKMGTHPGVP GSAGHVSIPR SWPSAHSVSN
210
ILGIRTFMEQ TG
Length:212
Mass (Da):23,026
Last modified:October 1, 2002 - v1
Checksum:i72749EF6802C164B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei212 – 2121Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB080657 mRNA. Translation: BAC10688.1.
UniGeneiMm.315502.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB080657 mRNA. Translation: BAC10688.1 .
UniGenei Mm.315502.

3D structure databases

ProteinModelPortali Q8K4Q1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:97485. Pax1.

Phylogenomic databases

HOVERGENi HBG009115.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q8K4Q1.
ExpressionAtlasi Q8K4Q1. baseline and differential.
Genevestigatori Q8K4Q1.

Family and domain databases

Gene3Di 1.10.10.10. 2 hits.
InterProi IPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00292. PAX. 1 hit.
[Graphical view ]
PRINTSi PR00027. PAIREDBOX.
SMARTi SM00351. PAX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  2. "Undulated short-tail deletion mutation in the mouse ablates Pax1 and leads to ectopic activation of neighboring Nkx2-2 in domains that normally express Pax1."
    Kokubu C., Wilm B., Kokubu T., Wahl M., Rodrigo I., Sakai N., Santagati F., Hayashizaki Y., Suzuki M., Yamamura K., Abe K., Imai K.
    Genetics 165:299-307(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8K4Q1_MOUSE
AccessioniPrimary (citable) accession number: Q8K4Q1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)