Q8K4G5 (ABLM1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Actin-binding LIM protein 1
Short name=abLIM-1

Alternative name(s):
Actin-binding LIM protein family member 1

Gene names

Name:	Ablim1
Synonyms:	Ablim, Kiaa0059

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	861 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May act as scaffold protein By similarity. May play a role in the development of the retina. Has been suggested to play a role in axon guidance. Ref.4 Ref.5
Subunit structure	Binds F-actin. Interacts with ABRA By similarity.
Subcellular location	Cytoplasm. Cytoplasm › cytoskeleton. Note: In a striped pattern along the myofibril axis in cardiac myocytes. Associated with the cytoskeleton. Ref.1
Tissue specificity	Isoform 1 is detected in adult retina, where it is highly expressed in the ganglion layer. Detected in rod inner segment. Isoform 2 is highly expressed in adult retina, brain, kidney and heart. Isoform 3 is highly expressed in adult retina, brain, kidney, liver, skeletal muscle, spleen and heart. Detected in embryonic retina, brain, spinal cord, peripheral sensory ganglia and thymus. Ref.1 Ref.4 Ref.5
Developmental stage	Isoform 1 is detected at low levels starting from E12 and remains constant until birth. After this levels increase strongly and expression remains high in adults. Isoform 2 and isoform 3 are expressed at a constant high level throughout development. Ref.1 Ref.5
Post-translational modification	Phosphorylated upon DNA damage, probably by ATM or ATR By similarity. Ref.1 Ref.6 Ref.7 Ref.8 Ref.9 Ref.10 Ref.11 Ref.12
Miscellaneous	Isoform 1 is not necessary for normal axon guidance.
Sequence similarities	Contains 1 HP (headpiece) domain. Contains 4 LIM zinc-binding domains.
Sequence caution	The sequence BAC65478.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton
Coding sequence diversity	Alternative splicing
Domain	Coiled coil LIM domain Repeat
Ligand	Actin-binding Metal-binding Zinc
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	axon guidance Inferred from direct assay Ref.4. Source: MGI cytoskeleton organization Inferred from electronic annotation. Source: InterPro positive regulation of transcription from RNA polymerase II promoter Inferred from mutant phenotype. Source: MGI
Cellular component	actin cytoskeleton Inferred from direct assay Ref.1. Source: MGI cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	actin binding Inferred from direct assay Ref.1. Source: MGI zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
Dlg4	Q62108	4	EBI-2307994,EBI-300895

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8K4G5-1)

Also known as: AbLIM-L;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8K4G5-2)

Also known as: AbLIM-M;

The sequence of this isoform differs from the canonical sequence as follows:
     1-81: MPSLLGLKCL...ELRFSSYDPS → MVKEK
     348-391: Missing.
     525-564: Missing.

Isoform 3 (identifier: Q8K4G5-3)

Also known as: AbLIM-S;

The sequence of this isoform differs from the canonical sequence as follows:
     1-316: Missing.

Isoform 4 (identifier: Q8K4G5-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-81: MPSLLGLKCL...ELRFSSYDPS → MVKEK
     348-391: Missing.
     525-564: Missing.
     616-662: Missing.

Note: No experimental confirmation available.

Isoform 5 (identifier: Q8K4G5-5)

The sequence of this isoform differs from the canonical sequence as follows:
     1-77: Missing.
     78-81: YDPS → MSTR
     301-345: DKHYHPSCAR...CKQSTKTEEK → VTEASRTWSH...SAREWFALSA
     346-861: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 861	861	Actin-binding LIM protein 1		PRO_0000075698
Regions
	Domain	97 – 156	60	LIM zinc-binding 1
	Domain	156 – 216	61	LIM zinc-binding 2
	Domain	224 – 283	60	LIM zinc-binding 3
	Domain	283 – 343	61	LIM zinc-binding 4
	Domain	793 – 861	69	HP
	Coiled coil	673 – 723	51	Potential
Amino acid modifications
	Modified residue	216	1	Phosphoserine Ref.11
	Modified residue	397	1	Phosphoserine Ref.12
	Modified residue	401	1	Phosphotyrosine By similarity
	Modified residue	411	1	Phosphoserine Ref.12
	Modified residue	417	1	Phosphotyrosine By similarity
	Modified residue	440	1	Phosphotyrosine Ref.10
	Modified residue	450	1	Phosphotyrosine By similarity
	Modified residue	454	1	Phosphotyrosine By similarity
	Modified residue	470	1	Phosphoserine By similarity
	Modified residue	473	1	Phosphothreonine By similarity
	Modified residue	475	1	Phosphoserine Ref.6 Ref.7 Ref.8 Ref.9 Ref.11
	Modified residue	477	1	Phosphothreonine By similarity
	Modified residue	479	1	Phosphoserine Ref.6
	Modified residue	483	1	Phosphotyrosine By similarity
	Modified residue	494	1	Phosphoserine Ref.9
	Modified residue	495	1	Phosphothreonine By similarity
	Modified residue	496	1	Phosphoserine Ref.12
	Modified residue	499	1	Phosphoserine By similarity
	Modified residue	502	1	Phosphoserine Ref.11
	Modified residue	505	1	Phosphotyrosine By similarity
	Modified residue	517	1	Phosphoserine By similarity
	Modified residue	671	1	Phosphoserine Ref.8
	Modified residue	723	1	Phosphoserine By similarity
	Modified residue	738	1	Phosphoserine By similarity
	Modified residue	789	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	1 – 316	316	Missing in isoform 3.		VSP_012103
	Alternative sequence	1 – 81	81	MPSLL…SYDPS → MVKEK in isoform 2 and isoform 4.		VSP_012104
	Alternative sequence	1 – 77	77	Missing in isoform 5.		VSP_012105
	Alternative sequence	78 – 81	4	YDPS → MSTR in isoform 5.		VSP_012106
	Alternative sequence	301 – 345	45	DKHYH…KTEEK → VTEASRTWSHIDLRWQGRSE ELRAWRHSIQSLRHQSAREW FALSA in isoform 5.		VSP_012107
	Alternative sequence	346 – 861	516	Missing in isoform 5.		VSP_012109
	Alternative sequence	348 – 391	44	Missing in isoform 2 and isoform 4.		VSP_012108
	Alternative sequence	525 – 564	40	Missing in isoform 2 and isoform 4.		VSP_012110
	Alternative sequence	616 – 662	47	Missing in isoform 4.		VSP_012111

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (AbLIM-L) [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 5E045F7CEF1D91EF	FASTA	861	96,805
	10 20 30 40 50 60 MPSLLGLKCL GKLCSSEIGK VPSPERASLR NSHRRLLIED LSVPETPDPA HRRRGTVIHL 70 80 90 100 110 120 VYLYSAGCGP PELRFSSYDP SVAHPQDPHH SSEKPVIHCH KCGEPCKGEV LRVQTKHFHI 130 140 150 160 170 180 KCFTCKVCGC DLAQGGFFIK NGDYLCTLDY QRMYGTRCHG CGEFVEGEVV TALGKTYHPN 190 200 210 220 230 240 CFACTICKRP FPPGDRVTFN GRDCLCQLCA QPMSSSPKEA SCSSNCAGCG RDIKNGQALL 250 260 270 280 290 300 ALDKQWHLGC FKCKSCGKVL TGEYISKDGS PYCEKDYQGL FGVKCEACHQ FITGKVLEAG 310 320 330 340 350 360 DKHYHPSCAR CSRCNQMFTE GEEMYLQGST VWHPDCKQST KTEEKLRPPN IPRSSSDFFY 370 380 390 400 410 420 PKSLIRRTGR SPALQLLSPP CLTNSNKNPR QPTRTSSESI YSRPGSSIPG SPGHTIYAKV 430 440 450 460 470 480 DNEILDYKDL AAIPKVKAIY DIERPDLITY EPFYTSGYED KQERQSLGES PRTLSPTPSA 490 500 510 520 530 540 EGYQDVRDRM IHRSTSQGSI NSPVYSRHSY TPTTSRSPQH FHRPELLSPG VHRWSPLRTS 550 560 570 580 590 600 SFSSTHSDSR PNPPFRHHFL PHVKGNEPSS GRNSPLPYRP DSRPLTPTYA QAPKHFHVPD 610 620 630 640 650 660 QGINIYRKPP IYKQHAALAA QSKASEDIIK FSKFPAAQAP DPNEIPKIET DHWPGPPSLA 670 680 690 700 710 720 AVGTDPRRRS SGREEDEEEL LRRRQLQEEQ LMKLNSGLGQ LILKEEMEKE SRERASLASR 730 740 750 760 770 780 YDSPLHSASH APSSKTSSLP GYGKNGLHRP VSTDFAQYNS YGDISGGVRD YQTLPDGHMP 790 800 810 820 830 840 AVRMDRGVSM PNMLEPKIFP YEMLMVTNRG RNKILRDVDR TRLERHLAPE VFWEIFGMSI 850 860 QEFDKLPLWR RNDMKKKAKL F
	Isoform 2 (AbLIM-M) [UniParc]. Checksum: 5B5B038DC13E8335	FASTA	701	78,960
	10 20 30 40 50 60 MVKEKVAHPQ DPHHSSEKPV IHCHKCGEPC KGEVLRVQTK HFHIKCFTCK VCGCDLAQGG 70 80 90 100 110 120 FFIKNGDYLC TLDYQRMYGT RCHGCGEFVE GEVVTALGKT YHPNCFACTI CKRPFPPGDR 130 140 150 160 170 180 VTFNGRDCLC QLCAQPMSSS PKEASCSSNC AGCGRDIKNG QALLALDKQW HLGCFKCKSC 190 200 210 220 230 240 GKVLTGEYIS KDGSPYCEKD YQGLFGVKCE ACHQFITGKV LEAGDKHYHP SCARCSRCNQ 250 260 270 280 290 300 MFTEGEEMYL QGSTVWHPDC KQSTKTEEKL RPTRTSSESI YSRPGSSIPG SPGHTIYAKV 310 320 330 340 350 360 DNEILDYKDL AAIPKVKAIY DIERPDLITY EPFYTSGYED KQERQSLGES PRTLSPTPSA 370 380 390 400 410 420 EGYQDVRDRM IHRSTSQGSI NSPVYSRHSY TPTTSRSPQH FHRPGNEPSS GRNSPLPYRP 430 440 450 460 470 480 DSRPLTPTYA QAPKHFHVPD QGINIYRKPP IYKQHAALAA QSKASEDIIK FSKFPAAQAP 490 500 510 520 530 540 DPNEIPKIET DHWPGPPSLA AVGTDPRRRS SGREEDEEEL LRRRQLQEEQ LMKLNSGLGQ 550 560 570 580 590 600 LILKEEMEKE SRERASLASR YDSPLHSASH APSSKTSSLP GYGKNGLHRP VSTDFAQYNS 610 620 630 640 650 660 YGDISGGVRD YQTLPDGHMP AVRMDRGVSM PNMLEPKIFP YEMLMVTNRG RNKILRDVDR 670 680 690 700 TRLERHLAPE VFWEIFGMSI QEFDKLPLWR RNDMKKKAKL F
	Isoform 3 (AbLIM-S) [UniParc]. Checksum: 4AC77999CAE0228B	FASTA	545	62,004
	10 20 30 40 50 60 MFTEGEEMYL QGSTVWHPDC KQSTKTEEKL RPPNIPRSSS DFFYPKSLIR RTGRSPALQL 70 80 90 100 110 120 LSPPCLTNSN KNPRQPTRTS SESIYSRPGS SIPGSPGHTI YAKVDNEILD YKDLAAIPKV 130 140 150 160 170 180 KAIYDIERPD LITYEPFYTS GYEDKQERQS LGESPRTLSP TPSAEGYQDV RDRMIHRSTS 190 200 210 220 230 240 QGSINSPVYS RHSYTPTTSR SPQHFHRPEL LSPGVHRWSP LRTSSFSSTH SDSRPNPPFR 250 260 270 280 290 300 HHFLPHVKGN EPSSGRNSPL PYRPDSRPLT PTYAQAPKHF HVPDQGINIY RKPPIYKQHA 310 320 330 340 350 360 ALAAQSKASE DIIKFSKFPA AQAPDPNEIP KIETDHWPGP PSLAAVGTDP RRRSSGREED 370 380 390 400 410 420 EEELLRRRQL QEEQLMKLNS GLGQLILKEE MEKESRERAS LASRYDSPLH SASHAPSSKT 430 440 450 460 470 480 SSLPGYGKNG LHRPVSTDFA QYNSYGDISG GVRDYQTLPD GHMPAVRMDR GVSMPNMLEP 490 500 510 520 530 540 KIFPYEMLMV TNRGRNKILR DVDRTRLERH LAPEVFWEIF GMSIQEFDKL PLWRRNDMKK KAKLF
	Isoform 4 [UniParc]. Checksum: 90BFFB081F2BF1D2	FASTA	654	74,052
	10 20 30 40 50 60 MVKEKVAHPQ DPHHSSEKPV IHCHKCGEPC KGEVLRVQTK HFHIKCFTCK VCGCDLAQGG 70 80 90 100 110 120 FFIKNGDYLC TLDYQRMYGT RCHGCGEFVE GEVVTALGKT YHPNCFACTI CKRPFPPGDR 130 140 150 160 170 180 VTFNGRDCLC QLCAQPMSSS PKEASCSSNC AGCGRDIKNG QALLALDKQW HLGCFKCKSC 190 200 210 220 230 240 GKVLTGEYIS KDGSPYCEKD YQGLFGVKCE ACHQFITGKV LEAGDKHYHP SCARCSRCNQ 250 260 270 280 290 300 MFTEGEEMYL QGSTVWHPDC KQSTKTEEKL RPTRTSSESI YSRPGSSIPG SPGHTIYAKV 310 320 330 340 350 360 DNEILDYKDL AAIPKVKAIY DIERPDLITY EPFYTSGYED KQERQSLGES PRTLSPTPSA 370 380 390 400 410 420 EGYQDVRDRM IHRSTSQGSI NSPVYSRHSY TPTTSRSPQH FHRPGNEPSS GRNSPLPYRP 430 440 450 460 470 480 DSRPLTPTYA QAPKHFHVPD QGINIYRKPP IYKQHGTDPR RRSSGREEDE EELLRRRQLQ 490 500 510 520 530 540 EEQLMKLNSG LGQLILKEEM EKESRERASL ASRYDSPLHS ASHAPSSKTS SLPGYGKNGL 550 560 570 580 590 600 HRPVSTDFAQ YNSYGDISGG VRDYQTLPDG HMPAVRMDRG VSMPNMLEPK IFPYEMLMVT 610 620 630 640 650 NRGRNKILRD VDRTRLERHL APEVFWEIFG MSIQEFDKLP LWRRNDMKKK AKLF
	Isoform 5 [UniParc]. Checksum: 08A6BFFDC99BB56B	FASTA	268	29,911
	10 20 30 40 50 60 MSTRVAHPQD PHHSSEKPVI HCHKCGEPCK GEVLRVQTKH FHIKCFTCKV CGCDLAQGGF 70 80 90 100 110 120 FIKNGDYLCT LDYQRMYGTR CHGCGEFVEG EVVTALGKTY HPNCFACTIC KRPFPPGDRV 130 140 150 160 170 180 TFNGRDCLCQ LCAQPMSSSP KEASCSSNCA GCGRDIKNGQ ALLALDKQWH LGCFKCKSCG 190 200 210 220 230 240 KVLTGEYISK DGSPYCEKDY QGLFGVKCEA CHQFITGKVL EAGVTEASRT WSHIDLRWQG 250 260 RSEELRAWRH SIQSLRHQSA REWFALSA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein." Roof D.J., Hayes A., Adamian M., Chishti A.H., Li T. J. Cell Biol. 138:575-588(1997) [PubMed: 9245787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3), TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, SUBCELLULAR LOCATION, PHOSPHORYLATION. Strain: C57BL/6.
[2]	"Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S., Nakajima D., Nagase T., Ohara O., Koga H. DNA Res. 10:35-48(2003) [PubMed: 12693553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4). Tissue: Brain.
[3]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5). Strain: C57BL/6J. Tissue: Head.
[4]	"A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system." Erkman L., Yates P.A., McLaughlin T., McEvilly R.J., Whisenhunt T., O'Connell S.M., Krones A.I., Kirby M.A., Rapaport D.H., Bermingham J.R. Jr., O'Leary D.D.M., Rosenfeld M.G. Neuron 28:779-792(2000) [PubMed: 11163266] [Abstract] Cited for: FUNCTION, TISSUE SPECIFICITY.
[5]	"Normal retinal development and retinofugal projections in mice lacking the retina-specific variant of actin-binding LIM domain protein." Lu C., Huang X., Ma H.F., Gooley J.J., Aparacio J., Roof D.J., Chen C., Chen D.F., Li T. Neuroscience 120:121-131(2003) [PubMed: 12849746] [Abstract] Cited for: FUNCTION, DEVELOPMENTAL STAGE, TISSUE SPECIFICITY, ALTERNATIVE SPLICING (ISOFORMS 1; 2 AND 3). Strain: C57BL/6.
[6]	"Phosphoproteomic analysis of the developing mouse brain." Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P. Mol. Cell. Proteomics 3:1093-1101(2004) [PubMed: 15345747] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475 AND SER-479, MASS SPECTROMETRY. Tissue: Embryonic brain.
[7]	"Proteomic analysis of in vivo phosphorylated synaptic proteins." Collins M.O., Yu L., Coba M.P., Husi H., Campuzano I., Blackstock W.P., Choudhary J.S., Grant S.G. J. Biol. Chem. 280:5972-5982(2005) [PubMed: 15572359] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475, MASS SPECTROMETRY. Tissue: Forebrain.
[8]	"Comprehensive identification of phosphorylation sites in postsynaptic density preparations." Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L. Mol. Cell. Proteomics 5:914-922(2006) [PubMed: 16452087] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475 AND SER-671, MASS SPECTROMETRY. Tissue: Brain.
[9]	"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis." Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H. J. Proteome Res. 7:3957-3967(2008) [PubMed: 18630941] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475 AND SER-494, MASS SPECTROMETRY. Tissue: Liver.
[10]	"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain." Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P. J. Proteome Res. 7:311-318(2008) [PubMed: 18034455] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-440, MASS SPECTROMETRY. Tissue: Brain.
[11]	"Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F., Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D., Gerrits B., Panse C., Schlapbach R., Mansuy I.M. Mol. Cell. Proteomics 6:283-293(2007) [PubMed: 17114649] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216; SER-475 AND SER-502, MASS SPECTROMETRY. Tissue: Brain cortex.
[12]	"Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) [PubMed: 17242355] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-397; SER-411 AND SER-496, MASS SPECTROMETRY. Tissue: Liver.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF404774 mRNA. Translation: AAM73705.1. AF404775 mRNA. Translation: AAM73706.1. AF404776 mRNA. Translation: AAM73707.1. AK122196 mRNA. Translation: BAC65478.1. Different initiation. AK029371 mRNA. Translation: BAC26424.1.
IPI	IPI00356147. IPI00403221. IPI00463138. IPI00467530. IPI01007625.
RefSeq	NP_001096647.1. NM_001103177.1. NP_001096648.1. NM_001103178.1. NP_848803.3. NM_178688.3.
UniGene	Mm.217161. Mm.446592.
3D structure databases
ProteinModelPortal	Q8K4G5.
SMR	Q8K4G5. Positions 61-344, 797-861.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8K4G5. 1 interaction.
STRING	Q8K4G5.
PTM databases
PhosphoSite	Q8K4G5.
Proteomic databases
PRIDE	Q8K4G5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000099294; ENSMUSP00000096897; ENSMUSG00000025085. ENSMUST00000111524; ENSMUSP00000107149; ENSMUSG00000025085. ENSMUST00000111546; ENSMUSP00000107172; ENSMUSG00000025085.
GeneID	226251.
KEGG	mmu:226251.
UCSC	uc008hzr.2. mouse. uc008hzs.2. mouse. uc008hzt.2. mouse. uc008hzz.1. mouse. uc009vbz.1. mouse.
Organism-specific databases
CTD	3983.
MGI	MGI:1194500. Ablim1.
Rouge	Search...
Phylogenomic databases
HOGENOM	HBG443863.
HOVERGEN	HBG031499.
InParanoid	Q8K4G5.
Gene expression databases
ArrayExpress	Q8K4G5.
Bgee	Q8K4G5.
CleanEx	MM_ABLIM1.
Genevestigator	Q8K4G5.
GermOnline	ENSMUSG00000025085. Mus musculus.
Family and domain databases
InterPro	IPR003128. Villin_headpiece. IPR001781. Znf_LIM. [Graphical view]
Gene3D	G3DSA:1.10.950.10. VHP. 1 hit. G3DSA:2.10.110.10. Znf_LIM. 4 hits.
KO	K07520.
Pfam	PF00412. LIM. 4 hits. PF02209. VHP. 1 hit. [Graphical view]
SMART	SM00132. LIM. 4 hits. SM00153. VHP. 1 hit. [Graphical view]
SUPFAM	SSF47050. VHP. 1 hit.
PROSITE	PS51089. HP. 1 hit. PS00478. LIM_DOMAIN_1. 4 hits. PS50023. LIM_DOMAIN_2. 4 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	378072.
SOURCE	Search...

Entry information

Entry name

ABLM1_MOUSE

Accession

Primary (citable) accession number: Q8K4G5
Secondary accession number(s): Q80U86 , Q8BIR9, Q8K4G3, Q8K4G4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 7, 2004
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program