Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein ABHD11

Gene

Abhd11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei133 – 1331Charge relay systemBy similarity
Active sitei229 – 2291Charge relay systemBy similarity
Active sitei288 – 2881Charge relay systemBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Protein family/group databases

ESTHERimouse-Abhd11. AlphaBeta_hydrolase.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ABHD11Curated (EC:3.-.-.-)
Alternative name(s):
Alpha/beta hydrolase domain-containing protein 11Curated
Short name:
Abhydrolase domain-containing protein 11Imported
Williams-Beuren syndrome chromosomal region 21 protein homolog
Gene namesi
Name:Abhd11Imported
Synonyms:Wbscr21
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1916008. Abhd11.

Subcellular locationi

GO - Cellular componenti

  • mitochondrion Source: MGI
Complete GO annotation...

Pathology & Biotechi

Chemistry

ChEMBLiCHEMBL1795090.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Protein ABHD11PRO_0000281004Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei79 – 791N6-succinyllysineCombined sources
Modified residuei196 – 1961N6-succinyllysineCombined sources

Proteomic databases

EPDiQ8K4F5.
MaxQBiQ8K4F5.
PaxDbiQ8K4F5.
PeptideAtlasiQ8K4F5.
PRIDEiQ8K4F5.

PTM databases

iPTMnetiQ8K4F5.
PhosphoSiteiQ8K4F5.

Expressioni

Tissue specificityi

Expressed in white adipose tissues.1 Publication

Inductioni

Up-regulated by rosiglitazone and down-regulated by high fat feeding.1 Publication

Gene expression databases

BgeeiENSMUSG00000040532.
CleanExiMM_ABHD11.
ExpressionAtlasiQ8K4F5. baseline and differential.
GenevisibleiQ8K4F5. MM.

Interactioni

Protein-protein interaction databases

IntActiQ8K4F5. 1 interaction.
MINTiMINT-4117817.
STRINGi10090.ENSMUSP00000043041.

Structurei

3D structure databases

ProteinModelPortaliQ8K4F5.
SMRiQ8K4F5. Positions 27-307.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AB hydrolase superfamily.Curated

Phylogenomic databases

eggNOGiKOG2382. Eukaryota.
COG0596. LUCA.
GeneTreeiENSGT00390000015880.
HOGENOMiHOG000028067.
HOVERGENiHBG080815.
InParanoidiQ8K4F5.
KOiK13703.
OMAiHIEKCVL.
OrthoDBiEOG091G0EP1.
PhylomeDBiQ8K4F5.
TreeFamiTF314071.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR000639. Epox_hydrolase-like.
[Graphical view]
PfamiPF12697. Abhydrolase_6. 1 hit.
[Graphical view]
PRINTSiPR00111. ABHYDROLASE.
PR00412. EPOXHYDRLASE.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K4F5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRWARAWRV PRGVLGASSP RRLAVPVTFC SSRSSGQENA DLRPLPLSYN
60 70 80 90 100
LLDGDATLPA IVFLHGLFGS KTNFNSLAKA MVQRTGRRVL TVDARNHGDS
110 120 130 140 150
PHSPDASYEA MSQDLQGLLP QLGLVPCVLV GHSMGGKTAM LLALQRPDVV
160 170 180 190 200
ERLVVVDISP VGTTPGSHIG AFIAAMKAVE IPEKVPHSQA RKLADKQLSS
210 220 230 240 250
VVKEAGIRQF LLTNLVEVGG RFSWRLNLDT LAQHLDKIMT FPQQREPYSG
260 270 280 290 300
PTLFLLGGNS TYVQPSHHSE IRRLFPQAQI QTVPNAGHWV HSDKPQDFMD

AVTSFLA
Length:307
Mass (Da):33,561
Last modified:October 1, 2002 - v1
Checksum:iB1FAB20B83545B77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF412033 mRNA. Translation: AAM62315.1.
BC069866 mRNA. Translation: AAH69866.1.
CCDSiCCDS19730.1.
RefSeqiNP_660250.1. NM_145215.2.
UniGeneiMm.389700.

Genome annotation databases

EnsembliENSMUST00000046999; ENSMUSP00000043041; ENSMUSG00000040532.
GeneIDi68758.
KEGGimmu:68758.
UCSCiuc008zxg.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF412033 mRNA. Translation: AAM62315.1.
BC069866 mRNA. Translation: AAH69866.1.
CCDSiCCDS19730.1.
RefSeqiNP_660250.1. NM_145215.2.
UniGeneiMm.389700.

3D structure databases

ProteinModelPortaliQ8K4F5.
SMRiQ8K4F5. Positions 27-307.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8K4F5. 1 interaction.
MINTiMINT-4117817.
STRINGi10090.ENSMUSP00000043041.

Chemistry

ChEMBLiCHEMBL1795090.

Protein family/group databases

ESTHERimouse-Abhd11. AlphaBeta_hydrolase.

PTM databases

iPTMnetiQ8K4F5.
PhosphoSiteiQ8K4F5.

Proteomic databases

EPDiQ8K4F5.
MaxQBiQ8K4F5.
PaxDbiQ8K4F5.
PeptideAtlasiQ8K4F5.
PRIDEiQ8K4F5.

Protocols and materials databases

DNASUi68758.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000046999; ENSMUSP00000043041; ENSMUSG00000040532.
GeneIDi68758.
KEGGimmu:68758.
UCSCiuc008zxg.2. mouse.

Organism-specific databases

CTDi83451.
MGIiMGI:1916008. Abhd11.

Phylogenomic databases

eggNOGiKOG2382. Eukaryota.
COG0596. LUCA.
GeneTreeiENSGT00390000015880.
HOGENOMiHOG000028067.
HOVERGENiHBG080815.
InParanoidiQ8K4F5.
KOiK13703.
OMAiHIEKCVL.
OrthoDBiEOG091G0EP1.
PhylomeDBiQ8K4F5.
TreeFamiTF314071.

Miscellaneous databases

PROiQ8K4F5.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000040532.
CleanExiMM_ABHD11.
ExpressionAtlasiQ8K4F5. baseline and differential.
GenevisibleiQ8K4F5. MM.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR000639. Epox_hydrolase-like.
[Graphical view]
PfamiPF12697. Abhydrolase_6. 1 hit.
[Graphical view]
PRINTSiPR00111. ABHYDROLASE.
PR00412. EPOXHYDRLASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiABHDB_MOUSE
AccessioniPrimary (citable) accession number: Q8K4F5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.