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Protein

Alstrom syndrome protein 1 homolog

Gene

Alms1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells (By similarity).By similarity

GO - Molecular functioni

  • alpha-actinin binding Source: MGI

GO - Biological processi

  • calcium-mediated signaling Source: MGI
  • cellular glucose homeostasis Source: MGI
  • cholesterol homeostasis Source: MGI
  • cilium assembly Source: MGI
  • endosomal transport Source: MGI
  • epithelial cell proliferation Source: MGI
  • establishment of planar polarity Source: MGI
  • fat cell differentiation Source: MGI
  • glucose homeostasis Source: MGI
  • inner ear receptor stereocilium organization Source: MGI
  • lipid metabolic process Source: MGI
  • negative regulation of apoptotic process Source: MGI
  • negative regulation of multicellular organism growth Source: MGI
  • ovulation Source: MGI
  • regulation of fat cell differentiation Source: MGI
  • regulation of stress fiber assembly Source: MGI
  • retinal rod cell development Source: MGI
  • sensory perception of sound Source: MGI
  • spermatid development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Alstrom syndrome protein 1 homolog
Gene namesi
Name:Alms1
Synonyms:Kiaa0328
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1934606. Alms1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton

Pathology & Biotechi

Disruption phenotypei

Mice display obesity, hypogonadism, hyperinsulinemia, retinal dysfunction and hearing loss.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 32513251Alstrom syndrome protein 1 homologPRO_0000225593Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1623 – 16231PhosphoserineBy similarity
Modified residuei1788 – 17881PhosphoserineBy similarity
Modified residuei1916 – 19161PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8K4E0.
PaxDbiQ8K4E0.
PRIDEiQ8K4E0.

PTM databases

iPTMnetiQ8K4E0.
PhosphoSiteiQ8K4E0.

Expressioni

Tissue specificityi

Ubiquitously expressed.1 Publication

Developmental stagei

Expressed at E7.5. At E8.0 expression is found in mesodermal- and ectodermal-derived layers. At E10.5 mainly detected in midbrain, hindbrain, forelimb and hindlimb. Also expressed at E15.5 and E18.5.1 Publication

Gene expression databases

BgeeiQ8K4E0.
CleanExiMM_ALMS1.
GenevisibleiQ8K4E0. MM.

Interactioni

GO - Molecular functioni

  • alpha-actinin binding Source: MGI

Protein-protein interaction databases

IntActiQ8K4E0. 1 interaction.
STRINGi10090.ENSMUSP00000071904.

Structurei

3D structure databases

ProteinModelPortaliQ8K4E0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati440 – 485461Add
BLAST
Repeati486 – 534492Add
BLAST
Repeati540 – 587483Add
BLAST
Repeati588 – 638514Add
BLAST
Repeati639 – 684465Add
BLAST
Repeati685 – 731476Add
BLAST
Repeati732 – 777467Add
BLAST
Repeati778 – 824478Add
BLAST
Repeati825 – 871479Add
BLAST
Repeati872 – 9174610Add
BLAST
Repeati918 – 9594211Add
BLAST
Repeati960 – 10054612Add
BLAST
Repeati1006 – 10484313Add
BLAST
Repeati1115 – 11634914Add
BLAST
Repeati1164 – 12084515Add
BLAST
Repeati1269 – 13144616Add
BLAST
Repeati1315 – 13624817Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni440 – 136292317 X 47 AA approximate tandem repeatAdd
BLAST
Regioni3129 – 3251123ALMS motifAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi2 – 8079Glu-richAdd
BLAST
Compositional biasi90 – 11324Pro-richAdd
BLAST
Compositional biasi2582 – 261837His-richAdd
BLAST

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IF7R. Eukaryota.
ENOG4111TD2. LUCA.
GeneTreeiENSGT00550000074751.
HOGENOMiHOG000089988.
HOVERGENiHBG080834.
InParanoidiQ8K4E0.
KOiK16741.
OMAiHREKPSI.
OrthoDBiEOG754HSH.
TreeFamiTF335596.

Family and domain databases

InterProiIPR028781. ALMS1.
IPR029299. ALMS_motif.
[Graphical view]
PANTHERiPTHR21553:SF22. PTHR21553:SF22. 1 hit.
PfamiPF15309. ALMS_motif. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8K4E0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEPEDLPWPD ELEEEEEEEE EEGEEEEGKK EVENASAAAT EEALTSEESG
60 70 80 90 100
RLEEFEEAGP DLDFNYESQR QESSDEEEDE LAKAWLQAHP DRPGSAFSLP
110 120 130 140 150
PPTPPPPPPP LSPRLRYTPV EHLGKTEVVP LTCRVWQQSS YQDNSRAQFS
160 170 180 190 200
NSSTMLLETG VRWGSEEDQR TESWHCLPQE RDSSQTLAMS QTEIGRVEGT
210 220 230 240 250
EVPDLPSQEG GLPAQSQCPG KKPKLNVLCS PLLVIQDNFA APDLPLLTCL
260 270 280 290 300
IQDQEEVEPD SLFQQSELEF APLRGIPDKS EDSEWLARPS EVSEALIQAT
310 320 330 340 350
SETSSDLANS CFSISQHPLT EGLQGKAESG VLTRCGDAKY SSLYENLGAQ
360 370 380 390 400
SERIAVLQRE VGCSNLGISQ ASPSSLPSFV PQEPTSEPEY HSSNLRMLRV
410 420 430 440 450
SPDTLLTTHT HSAGSADQKI GAAVVSSAYS QEIKPGSFHQ EELPDRHLNE
460 470 480 490 500
EIRKVSPALR TAGQKPEMLP VQSSSYSKGM KSIFYQHPVS HGHQGKEPLS
510 520 530 540 550
VSAVCGSAGN KAFHQLSTLS DSLLTEETWP VSVIPGLGNQ KTPLPSEFSL
560 570 580 590 600
SYSHRGKNLP EDVVKVSTDS GSAHKKADIL TASSRTYQHK MKPANIYHQE
610 620 630 640 650
LPDSRVPIGT RKVAFESGPA GQKSGVSHPY GEMPSVFYQQ GLPDRHSAKS
660 670 680 690 700
PTKTFIPGPA DQKTDLSPVP PTSSSHAEKP VSPYQLTLPG SHLPEDVFKA
710 720 730 740 750
SSVCKSSDEL SGITALTSAS YSYKGRPNSS YQQKFPDSHL NEEAQKILGT
760 770 780 790 800
TGTVDQKTVT PTMSSSFLQK EKPSIFYQQT LPDGGLSEED LQVSAVPWPA
810 820 830 840 850
DQNIAIPTVT SAAFSQREKP RIFYQQTLSV DRLPGEPLNV LGTSGPPDQN
860 870 880 890 900
TGAPTVTPSS YFPGEESIIF YQAGFPGNTL SAMSFKVPRI SGSTEQTNVT
910 920 930 940 950
TGSSSSYSVG EKSIIFYHQA LPDGRLPQEA SPAPADLNTG EPPMYLASCS
960 970 980 990 1000
VGVKPIIFYQ QPMSDSQRTK GHKESDVPGP TDQKTGIATV HSTSQSYIGR
1010 1020 1030 1040 1050
RTVSYQKEFP DLSEKALKVL GDVGSTEQKT QIPVVSSALL HKEGPSAYQE
1060 1070 1080 1090 1100
DLPDLTEEPL QILGVSEEVS SSSYQRKLPD HIEVFLKSVG SGSADRKTGA
1110 1120 1130 1140 1150
QIVSSSREKS SGFHQQELPN TGGDAVDAFH PEPVVQEVRK VQTPGAPAGP
1160 1170 1180 1190 1200
SSSHFHKEKL SDYQKASPHR DLTESSLKAS TVPGLSDQKK KPAVSSGFCL
1210 1220 1230 1240 1250
HKEKHEISAS ALLNCQTAEL LTVTQRSCLH REDPAISTVI KPDDQKIPLP
1260 1270 1280 1290 1300
TTFHGSSDQK VKPVIFVQKQ LRDRDQSEDI PKISTVSEPT VVNTVLPVLL
1310 1320 1330 1340 1350
PGSYSHREKS DSFYPQELPD GHLTEVDLKV SSGLGQADQI SGLPTGIPGT
1360 1370 1380 1390 1400
YSHSEKHQLI SEHVQELMDN LNSSESSCLS VDSMPLNSQI DDGVIICKPE
1410 1420 1430 1440 1450
SLGFANAGCE EMQNIDRGSK TLKEIQTLLM EAENMALKRC NFSVPLVPFR
1460 1470 1480 1490 1500
DVNDVSFIRS KKVVCFKESS TTDVCTQRES FVEEVPHIEY VQKDIGTQTN
1510 1520 1530 1540 1550
LKYQRGVGNW EFISSATFRS PLQEAEGTAR MAYDETFRQY KAARSVMRSE
1560 1570 1580 1590 1600
PEGCSTGIGN KMIIPMMTII KSDSSSDVSD GCCSWDNNLP ESLESVSDVF
1610 1620 1630 1640 1650
LNFFPYTSPK TSITDSREEE WLSESEDGYG STDSLAAHVK YLLQCETSLN
1660 1670 1680 1690 1700
QAKQILKNAE EEEYRVRTQA WNLKFNLGRD RGYSISELNE DDRRKVEEIK
1710 1720 1730 1740 1750
AKLFGHGRAT HMSEGLRSPQ GIGCLPEAVC SRIIIESHEK GCFRTLTAEQ
1760 1770 1780 1790 1800
PRPDSCHCAF RSVEPSDLIR GHRSPSSWRG RHINLSRSIE QSNPCFKVGS
1810 1820 1830 1840 1850
SFQLQSHPPF QKLLPDDIKI SKGVGMPVHA YMDPQPSELV EPTCVPAKEM
1860 1870 1880 1890 1900
DFPSSSQILP PEPKKQFTTA ITFSSHEHSE CISDSSGCKV GVTADSQCSG
1910 1920 1930 1940 1950
PSLGVFKPHI PEEQISPRDL KQKTSFQSSL ERHGSTPVTI LADGSRQRQK
1960 1970 1980 1990 2000
LPVDFEHSHQ KEKLLQRLGF KVSHSEPNVS TNVSNFKGVQ FSGKDTIVSQ
2010 2020 2030 2040 2050
DKLTSTVEVK EKNVTVTPDL PSCIFLEQPE LFEESHTPHT DLQMRKYPSP
2060 2070 2080 2090 2100
SCPEIASRIF LEQPKLSEQS KAPHVDREIR EDHSFFPKCQ DYIVADPSPD
2110 2120 2130 2140 2150
FPDQQQCKPP DVVGHTRKQN SLLSEGQDYE LEEVQHIPQS YFSNMVNVEA
2160 2170 2180 2190 2200
KVSDAISQSA PDHCTAASTP PSNRKALSCV RITLCPKTSS KLDSGTLGER
2210 2220 2230 2240 2250
FHSLDPASKT RINSEFNSDL RIISSRSLEP TSKLLTCKPV AQDQESLVFL
2260 2270 2280 2290 2300
GPKSPLDLQV AQSSLPDSKT IFQDLKTKPP QNSQIVTSRQ TQVNISHLEG
2310 2320 2330 2340 2350
YSKPEGTPVS ADGSQEQSKV SFTTSFGKLS SDAITQITTE SPEKTTFSSE
2360 2370 2380 2390 2400
IFIHADDRGQ GILDPMAQKP SRFASSSSVQ QIPASHGKDA QPVLLPYKPS
2410 2420 2430 2440 2450
GSSKMYYVPL LKRVPSYLDS KSDTTVESSH SGSNDAIAPD FPPQMLGTRD
2460 2470 2480 2490 2500
DDLSNTVNIK HKEGIYSKRA ATKGKNPSQK GDAAAPVQMP ITWDENVLDE
2510 2520 2530 2540 2550
NQEEVISRGV VIKMAGPEEM SSLEKDLAGP SDITVQDRKT ENLPDTKSIK
2560 2570 2580 2590 2600
QKEGSLEIES ECHSAFENTA HSVFRSAKFY FHHPVHLPHE QDFCHESLGR
2610 2620 2630 2640 2650
SVFMQHSWKD FFHHHSGHSC LPPPGPSSDK LDKTKMDYTR IKSLSINLNL
2660 2670 2680 2690 2700
GEHEKIHTIK NQARDPKGKR QANEQKKDQK VTPELTTECP VSLNELWNRY
2710 2720 2730 2740 2750
QERQKQQNPS GACDTKELSL VERLDRLAKL LQNPITHSLR ASESAQDDSR
2760 2770 2780 2790 2800
GGHRAREWTG RRQQKQKGKQ HRKWSKSLER GQSTGDFRKS KVFSPHQGGK
2810 2820 2830 2840 2850
SSQFKIEQIK LDKYILRKEP GFNNVSNTSL DSRPSEESVS LTDSPNIFSS
2860 2870 2880 2890 2900
TDSPVDSDVL TPTDRDMPLN ERSSSISTID TVRLIQAFGQ DRLSLSPRRI
2910 2920 2930 2940 2950
KLYSTVTSQR RRYLEQPCKH NRKALNTACP QMTSEHSRRR HIQVANHMTS
2960 2970 2980 2990 3000
SDSVSSPGSL LSLDSALSNE ETVRMVSKGV QAGNLEIVAG VKKYTQDVGV
3010 3020 3030 3040 3050
TFPTPSSSEA RLEEDSDVTS SSEEKAKEKK FLSNYLQTKN LRKNKPNPCA
3060 3070 3080 3090 3100
GVSWFVPVES GQSGSKKENL PKIYRPVISW FEPVTKTKPW REPLREQNWQ
3110 3120 3130 3140 3150
AQCMNSRGSL GGPGRDSGQV SLRPFVRATL QESLQLHRPD FISHSGERIK
3160 3170 3180 3190 3200
RLKLLVQERK LQSLFQSERE ALFHSARPLP RRVLLAVQKN KPIGKKEMIQ
3210 3220 3230 3240 3250
RTRRIYEQLP EVKKKREEEK RKSEYKSYWL RAQHYKMKVT NHLLGRKVPW

D
Length:3,251
Mass (Da):360,215
Last modified:July 27, 2011 - v2
Checksum:i560D2B0650DDD0FB
GO
Isoform 2 (identifier: Q8K4E0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-2947: Missing.

Note: No experimental confirmation available.
Show »
Length:304
Mass (Da):34,832
Checksum:iE844C8A038C87ECE
GO

Sequence cautioni

The sequence BAD32212.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti26 – 261E → Y in AAM62320 (PubMed:11941369).Curated
Sequence conflicti2708 – 27103NPS → SPC in AAM62320 (PubMed:11941369).Curated
Sequence conflicti3017 – 30171D → G in BAD32212 (PubMed:15368895).Curated
Sequence conflicti3060 – 30601S → N in BAD32212 (PubMed:15368895).Curated
Sequence conflicti3077 – 30771V → G in BAD32212 (PubMed:15368895).Curated
Sequence conflicti3229 – 32291W → R in BAD32212 (PubMed:15368895).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 29472947Missing in isoform 2. 1 PublicationVSP_017350Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF425257 mRNA. Translation: AAM62320.1.
AK172934 mRNA. Translation: BAD32212.1. Different initiation.
AC104743 Genomic DNA. No translation available.
AC162313 Genomic DNA. No translation available.
AK041679 mRNA. Translation: BAC31030.1.
CCDSiCCDS20298.1. [Q8K4E0-1]
RefSeqiNP_660258.2. NM_145223.2. [Q8K4E0-1]
UniGeneiMm.246967.
Mm.422971.

Genome annotation databases

EnsembliENSMUST00000072018; ENSMUSP00000071904; ENSMUSG00000063810. [Q8K4E0-1]
GeneIDi236266.
KEGGimmu:236266.
UCSCiuc009cpz.1. mouse. [Q8K4E0-1]
uc009cqe.1. mouse. [Q8K4E0-2]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF425257 mRNA. Translation: AAM62320.1.
AK172934 mRNA. Translation: BAD32212.1. Different initiation.
AC104743 Genomic DNA. No translation available.
AC162313 Genomic DNA. No translation available.
AK041679 mRNA. Translation: BAC31030.1.
CCDSiCCDS20298.1. [Q8K4E0-1]
RefSeqiNP_660258.2. NM_145223.2. [Q8K4E0-1]
UniGeneiMm.246967.
Mm.422971.

3D structure databases

ProteinModelPortaliQ8K4E0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8K4E0. 1 interaction.
STRINGi10090.ENSMUSP00000071904.

PTM databases

iPTMnetiQ8K4E0.
PhosphoSiteiQ8K4E0.

Proteomic databases

MaxQBiQ8K4E0.
PaxDbiQ8K4E0.
PRIDEiQ8K4E0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000072018; ENSMUSP00000071904; ENSMUSG00000063810. [Q8K4E0-1]
GeneIDi236266.
KEGGimmu:236266.
UCSCiuc009cpz.1. mouse. [Q8K4E0-1]
uc009cqe.1. mouse. [Q8K4E0-2]

Organism-specific databases

CTDi7840.
MGIiMGI:1934606. Alms1.
RougeiSearch...

Phylogenomic databases

eggNOGiENOG410IF7R. Eukaryota.
ENOG4111TD2. LUCA.
GeneTreeiENSGT00550000074751.
HOGENOMiHOG000089988.
HOVERGENiHBG080834.
InParanoidiQ8K4E0.
KOiK16741.
OMAiHREKPSI.
OrthoDBiEOG754HSH.
TreeFamiTF335596.

Miscellaneous databases

PROiQ8K4E0.
SOURCEiSearch...

Gene expression databases

BgeeiQ8K4E0.
CleanExiMM_ALMS1.
GenevisibleiQ8K4E0. MM.

Family and domain databases

InterProiIPR028781. ALMS1.
IPR029299. ALMS_motif.
[Graphical view]
PANTHERiPTHR21553:SF22. PTHR21553:SF22. 1 hit.
PfamiPF15309. ALMS_motif. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome."
    Collin G.B., Marshall J.D., Ikeda A., So W.V., Russell-Eggitt I., Maffei P., Beck S., Boerkoel C., Sicolo N., Martin M., Nishina P.M., Naggert J.K.
    Nat. Genet. 31:74-78(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
    Strain: C57BL/6J.
    Tissue: Brain.
  2. "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
    DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Embryonic tail.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2941-3251 (ISOFORMS 1/2).
    Strain: C57BL/6J.
    Tissue: Thymus.
  5. Cited for: POSSIBLE FUNCTION, DEVELOPMENTAL STAGE, DISRUPTION PHENOTYPE.
  6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1916, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Spleen and Testis.

Entry informationi

Entry nameiALMS1_MOUSE
AccessioniPrimary (citable) accession number: Q8K4E0
Secondary accession number(s): E9QKT8, Q6A084, Q8C9N9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: July 27, 2011
Last modified: June 8, 2016
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.