Reviewed, UniProtKB/Swiss-Prot Q8K479 (C1QT5_MOUSE)

Names and origin

Protein names

Recommended name:
    Complement C1q tumor necrosis factor-related protein 5

Gene names

Name:	C1qtnf5
Synonyms:	Ctrp5

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	243 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Secreted Probable.
Sequence similarities	Contains 1 C1q domain. Contains 1 collagen-like domain.

Ontologies

Keywords
Cellular component	Secreted
Domain	Collagen Signal
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 15	15	By similarity
	Chain	16 – 243	228	Complement C1q tumor necrosis factor-related protein 5		PRO_0000003536
Regions
	Domain	30 – 95	66	Collagen-like
	Domain	99 – 243	145	C1q

Sequences

	Sequence		Length	Mass (Da)
	Q8K479-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 9F4D5804349791D9	FASTA	243	25,437
	10 20 30 40 50 60 MRPLLALLLL GLVSGSPPLD DNKIPSLCPG QPGLPGTPGH HGSQGLPGRD GRDGRDGAPG 70 80 90 100 110 120 APGEKGEGGR PGLPGPRGEP GPRGEAGPMG AIGPAGECSV PPRSAFSAKR SESRVPPPAD 130 140 150 160 170 180 TPLPFDRVLL NEQGHYDPTT GKFTCQVPGV YYFAVHATVY RASLQFDLVK NGQSIASFFQ 190 200 210 220 230 240 YFGGWPKPAS LSGGAMVRLE PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP VFA

References

[1]	"Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6." Kameya S., Hawes N.L., Chang B., Heckenlively J.R., Naggert J.K., Nishina P.M. Hum. Mol. Genet. 11:1879-1886(2002) [PubMed: 12140190] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: C57BL/6J.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF469650 mRNA. Translation: AAM89217.1.
IPI	IPI00170175.
RefSeq	NP_001035721.1. NP_001035722.1. NP_663588.2.
UniGene	Mm.227110
3D structure databases
HSSP	HSSP built from PDB template 1GR3 based on UniProtKB Q03692.
ModBase	Search...
Genome annotation databases
Ensembl	ENSMUSG00000079592. Mus musculus. [Contig view]
GeneID	235312.
KEGG	mmu:235312.
Organism-specific databases
MGI	MGI:2385958. C1qtnf5.
Phylogenomic databases
HOVERGEN	Q8K479.
OMA	Q8K479. QGHYDAT.
Family and domain databases
InterPro	IPR001073. C1q. IPR008160. Collagen. IPR008983. Tumour_necrosis_fac-like. [Graphical view]
Gene3D	G3DSA:2.60.120.40. Tumour_necrosis_fac-like. 1 hit.
Pfam	PF00386. C1q. 1 hit. PF01391. Collagen. 1 hit. [Graphical view]
PRINTS	PR00007. COMPLEMNTC1Q.
SMART	SM00110. C1Q. 1 hit. [Graphical view]
PROSITE	PS50871. C1Q. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	382581.
SOURCE	Search...

Entry information

Entry name

C1QT5_MOUSE

Accession

Primary (citable) accession number: Q8K479

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2005
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)