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Q8K3G0

- Q8K3G0_RAT

UniProt

Q8K3G0 - Q8K3G0_RAT

Protein
Submitted name:

TNF-related apoptosis inducing ligand

Gene

Tnfsf10

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. immune response Source: InterPro
    2. male gonad development Source: RGD
    3. positive regulation of apoptotic process Source: RGD
    4. response to insulin Source: RGD

    Keywords - Molecular functioni

    CytokineSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    TNF-related apoptosis inducing ligandImported
    Gene namesi
    Name:Tnfsf10Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi628734. Tnfsf10.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: UniProtKB-KW
    2. membrane Source: InterPro

    PTM / Processingi

    PTM databases

    PhosphoSiteiQ8K3G0.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8K3G0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K3G0.
    SMRiQ8K3G0. Positions 123-287.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG059007.
    InParanoidiQ8K3G0.
    KOiK04721.
    PhylomeDBiQ8K3G0.

    Family and domain databases

    Gene3Di2.60.120.40. 1 hit.
    InterProiIPR021184. TNF_CS.
    IPR006052. TNF_dom.
    IPR017355. TNF_ligand_10/11.
    IPR008983. Tumour_necrosis_fac-like_dom.
    [Graphical view]
    PfamiPF00229. TNF. 1 hit.
    [Graphical view]
    PIRSFiPIRSF038013. TNF10_TNF11. 1 hit.
    SMARTiSM00207. TNF. 1 hit.
    [Graphical view]
    SUPFAMiSSF49842. SSF49842. 1 hit.
    PROSITEiPS00251. TNF_1. 1 hit.
    PS50049. TNF_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8K3G0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASTGNLKGP SFSQHFTMTV ICIVLLQVLL QALTVAVTYM YFNNEVKQLQ    50
    DNYSKIGLAC FSKEDGDFWD STDEGILNRP CLQVKRQLYQ LIEEVTLRTF 100
    EKTISTVPEK QLSTPPLPRG RRPQRVAAHI TGITRRSNLA LIPISKDGKT 150
    LGQKIETWES SRRGHSFLNH VHLRNGELVI QEEGLYYIYS QTYYRFKEAK 200
    EASKTVSKDG GRIKQMVQYI YKYTSYPDPI LLMKSARNSC WSREAEYGLY 250
    SIYQGGLFEL KENDRIFVSV TNEHLMDLDH EASFFGA 287
    Length:287
    Mass (Da):32,980
    Last modified:October 1, 2002 - v1
    Checksum:iCA4F5B5D7C833FEC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY115578 mRNA. Translation: AAM49797.1.
    RefSeqiNP_663714.1. NM_145681.1.
    UniGeneiRn.83627.

    Genome annotation databases

    GeneIDi246775.
    KEGGirno:246775.
    UCSCiRGD:628734. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY115578 mRNA. Translation: AAM49797.1 .
    RefSeqi NP_663714.1. NM_145681.1.
    UniGenei Rn.83627.

    3D structure databases

    ProteinModelPortali Q8K3G0.
    SMRi Q8K3G0. Positions 123-287.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q8K3G0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 246775.
    KEGGi rno:246775.
    UCSCi RGD:628734. rat.

    Organism-specific databases

    CTDi 8743.
    RGDi 628734. Tnfsf10.

    Phylogenomic databases

    HOVERGENi HBG059007.
    InParanoidi Q8K3G0.
    KOi K04721.
    PhylomeDBi Q8K3G0.

    Miscellaneous databases

    NextBioi 623869.

    Gene expression databases

    Genevestigatori Q8K3G0.

    Family and domain databases

    Gene3Di 2.60.120.40. 1 hit.
    InterProi IPR021184. TNF_CS.
    IPR006052. TNF_dom.
    IPR017355. TNF_ligand_10/11.
    IPR008983. Tumour_necrosis_fac-like_dom.
    [Graphical view ]
    Pfami PF00229. TNF. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF038013. TNF10_TNF11. 1 hit.
    SMARTi SM00207. TNF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49842. SSF49842. 1 hit.
    PROSITEi PS00251. TNF_1. 1 hit.
    PS50049. TNF_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Rattus norvegicus TNF-related apoptosis inducing ligand (TRAIL)."
      Mueller A.M., Giegerich G.
      Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DAImported.

    Entry informationi

    Entry nameiQ8K3G0_RAT
    AccessioniPrimary (citable) accession number: Q8K3G0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)