##gff-version 3
Q8K3F2	UniProtKB	Signal peptide	1	24	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8K3F2	UniProtKB	Propeptide	25	143	.	.	.	ID=PRO_0000437089;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q8K3F2	UniProtKB	Chain	144	568	.	.	.	ID=PRO_0000028841;Note=Matrix metalloproteinase-21	
Q8K3F2	UniProtKB	Repeat	329	388	.	.	.	Note=Hemopexin 1	
Q8K3F2	UniProtKB	Repeat	390	446	.	.	.	Note=Hemopexin 2	
Q8K3F2	UniProtKB	Repeat	447	495	.	.	.	Note=Hemopexin 3	
Q8K3F2	UniProtKB	Repeat	502	558	.	.	.	Note=Hemopexin 4	
Q8K3F2	UniProtKB	Motif	110	117	.	.	.	Note=Cysteine switch;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q8K3F2	UniProtKB	Active site	283	283	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10095	
Q8K3F2	UniProtKB	Binding site	112	112	.	.	.	Note=In inhibited form;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q8K3F2	UniProtKB	Binding site	282	282	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10095	
Q8K3F2	UniProtKB	Binding site	286	286	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10095	
Q8K3F2	UniProtKB	Binding site	292	292	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10095	
Q8K3F2	UniProtKB	Glycosylation	371	371	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8K3F2	UniProtKB	Disulfide bond	328	559	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q8K3F2	UniProtKB	Mutagenesis	177	177	.	.	.	Note=Miri mutant%2C animals exhibit visceral heterotaxy%2C with heart defects commonly associated with heterotaxy. W->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26437029;Dbxref=PMID:26437029	
Q8K3F2	UniProtKB	Mutagenesis	225	225	.	.	.	Note=Embryos have congenital heart defects with transposition of the great artery%2C 61%25 exhibiting situs inversus or heterotaxy and 39%25 exhibiting situs solitus. This mutation corresponds to the pathological variant 'T-226' identified in humans. I->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26437028;Dbxref=PMID:26437028	
Q8K3F2	UniProtKB	Mutagenesis	325	325	.	.	.	Note=Koli mutant%2C animals exhibit visceral heterotaxy%2C with heart defects commonly associated with heterotaxy. Y->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26437029;Dbxref=PMID:26437029