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Protein

Ras association domain-containing protein 9

Gene

Rassf9

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in regulating vesicuar trafficking in cells.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ras association domain-containing protein 9
Alternative name(s):
PAM COOH-terminal interactor protein 1
Short name:
P-CIP1
Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor
Gene namesi
Name:Rassf9
Synonyms:Pamci, Pcip1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:2384307. Rassf9.

Subcellular locationi

  • Endosome

  • Note: Accumulates on perinuclear endosomes.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002994531 – 435Ras association domain-containing protein 9Add BLAST435

Proteomic databases

PaxDbiQ8K342.
PRIDEiQ8K342.

PTM databases

PhosphoSitePlusiQ8K342.

Expressioni

Gene expression databases

BgeeiENSMUSG00000044921.
GenevisibleiQ8K342. MM.

Interactioni

Subunit structurei

Interacts with PAM.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054767.

Structurei

3D structure databases

ProteinModelPortaliQ8K342.
SMRiQ8K342.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 119Ras-associatingPROSITE-ProRule annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili195 – 291Sequence analysisAdd BLAST97

Sequence similaritiesi

Contains 1 Ras-associating domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG1574. Eukaryota.
ENOG410XPWB. LUCA.
GeneTreeiENSGT00510000047164.
HOGENOMiHOG000065674.
HOVERGENiHBG053178.
InParanoidiQ8K342.
KOiK09856.
OMAiEVKSVCI.
OrthoDBiEOG091G07DQ.
PhylomeDBiQ8K342.
TreeFamiTF326923.

Family and domain databases

InterProiIPR033593. N-RASSF.
IPR000159. RA_dom.
IPR033633. RASSF9.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR15286. PTHR15286. 1 hit.
PTHR15286:SF10. PTHR15286:SF10. 1 hit.
SMARTiSM00314. RA. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS50200. RA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K342-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPFGRNLLK TRHKNRSPTK DMDPEEKEIV VWVCQDEKIV CGLTKRTTSI
60 70 80 90 100
DVIQALLEEH EATFGEKRFL LGKASDYCIV EKWRGSERAL PPLTRILKLW
110 120 130 140 150
KAWGDEQPNM QFVLVKTDAF LPVPLWRTAE TKLVQNNEKP WELSPANYMK
160 170 180 190 200
TLPPDKQKRI VRKTFRKLAK IRQDTSSHDR DNMECLVHLI ISQDHTIHQQ
210 220 230 240 250
VQRMKELDME IEKCEAKIHL DRVGNDGANY VHEAYLMPRL SDEEQKLDIQ
260 270 280 290 300
AEINQTLEDL NDSEGMAQLE EQLQYYRALI DKLSAEIERE VKGAGIDGIE
310 320 330 340 350
DMEGAAACEL ENSDLESVKC DLETSMKAGL TIHSHLSGIQ REIKYSDSLL
360 370 380 390 400
QMKAREYELL AKEFSSLHIS NKDGCQGKEN RGKEAEAPSS NGETPPLTQR
410 420 430
VFNIYTNDTD SDTGISSNHS QDSETTLGDV LLLAT
Length:435
Mass (Da):49,582
Last modified:October 1, 2002 - v1
Checksum:i4F36702F273DEE49
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti370S → N in BAC28302 (PubMed:16141072).Curated1
Sequence conflicti409T → A in BAC28302 (PubMed:16141072).Curated1
Sequence conflicti429D → N in BAC28302 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033464 mRNA. Translation: BAC28302.1.
AK041688 mRNA. Translation: BAC31033.1.
BC028805 mRNA. Translation: AAH28805.1.
CCDSiCCDS36048.1.
RefSeqiNP_666352.1. NM_146240.4.
UniGeneiMm.282672.

Genome annotation databases

EnsembliENSMUST00000055355; ENSMUSP00000054767; ENSMUSG00000044921.
GeneIDi237504.
KEGGimmu:237504.
UCSCiuc007gyf.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033464 mRNA. Translation: BAC28302.1.
AK041688 mRNA. Translation: BAC31033.1.
BC028805 mRNA. Translation: AAH28805.1.
CCDSiCCDS36048.1.
RefSeqiNP_666352.1. NM_146240.4.
UniGeneiMm.282672.

3D structure databases

ProteinModelPortaliQ8K342.
SMRiQ8K342.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054767.

PTM databases

PhosphoSitePlusiQ8K342.

Proteomic databases

PaxDbiQ8K342.
PRIDEiQ8K342.

Protocols and materials databases

DNASUi237504.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000055355; ENSMUSP00000054767; ENSMUSG00000044921.
GeneIDi237504.
KEGGimmu:237504.
UCSCiuc007gyf.1. mouse.

Organism-specific databases

CTDi9182.
MGIiMGI:2384307. Rassf9.

Phylogenomic databases

eggNOGiKOG1574. Eukaryota.
ENOG410XPWB. LUCA.
GeneTreeiENSGT00510000047164.
HOGENOMiHOG000065674.
HOVERGENiHBG053178.
InParanoidiQ8K342.
KOiK09856.
OMAiEVKSVCI.
OrthoDBiEOG091G07DQ.
PhylomeDBiQ8K342.
TreeFamiTF326923.

Miscellaneous databases

PROiQ8K342.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000044921.
GenevisibleiQ8K342. MM.

Family and domain databases

InterProiIPR033593. N-RASSF.
IPR000159. RA_dom.
IPR033633. RASSF9.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR15286. PTHR15286. 1 hit.
PTHR15286:SF10. PTHR15286:SF10. 1 hit.
SMARTiSM00314. RA. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS50200. RA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRASF9_MOUSE
AccessioniPrimary (citable) accession number: Q8K342
Secondary accession number(s): Q8BZV4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 1, 2002
Last modified: November 2, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.