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Q8K342

- RASF9_MOUSE

UniProt

Q8K342 - RASF9_MOUSE

Protein

Ras association domain-containing protein 9

Gene

Rassf9

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    May play a role in regulating vesicuar trafficking in cells.By similarity

    GO - Biological processi

    1. signal transduction Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ras association domain-containing protein 9
    Alternative name(s):
    PAM COOH-terminal interactor protein 1
    Short name:
    P-CIP1
    Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor
    Gene namesi
    Name:Rassf9
    Synonyms:Pamci, Pcip1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 10

    Organism-specific databases

    MGIiMGI:2384307. Rassf9.

    Subcellular locationi

    Endosome
    Note: Accumulates on perinuclear endosomes.By similarity

    GO - Cellular componenti

    1. cytosol Source: UniProtKB
    2. endosome Source: UniProtKB
    3. trans-Golgi network transport vesicle membrane Source: UniProtKB

    Keywords - Cellular componenti

    Endosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 435435Ras association domain-containing protein 9PRO_0000299453Add
    BLAST

    Proteomic databases

    PRIDEiQ8K342.

    Expressioni

    Gene expression databases

    BgeeiQ8K342.
    GenevestigatoriQ8K342.

    Interactioni

    Subunit structurei

    Interacts with PAM.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K342.
    SMRiQ8K342. Positions 28-117.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini25 – 11995Ras-associatingPROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili195 – 29197Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Contains 1 Ras-associating domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG237393.
    GeneTreeiENSGT00510000047164.
    HOGENOMiHOG000065674.
    HOVERGENiHBG053178.
    InParanoidiQ8K342.
    KOiK09856.
    OMAiDHTIHQQ.
    OrthoDBiEOG7MSMNT.
    PhylomeDBiQ8K342.
    TreeFamiTF326923.

    Family and domain databases

    InterProiIPR000159. Ras-assoc.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view]
    SMARTiSM00314. RA. 1 hit.
    [Graphical view]
    SUPFAMiSSF54236. SSF54236. 1 hit.
    PROSITEiPS50200. RA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8K342-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPFGRNLLK TRHKNRSPTK DMDPEEKEIV VWVCQDEKIV CGLTKRTTSI    50
    DVIQALLEEH EATFGEKRFL LGKASDYCIV EKWRGSERAL PPLTRILKLW 100
    KAWGDEQPNM QFVLVKTDAF LPVPLWRTAE TKLVQNNEKP WELSPANYMK 150
    TLPPDKQKRI VRKTFRKLAK IRQDTSSHDR DNMECLVHLI ISQDHTIHQQ 200
    VQRMKELDME IEKCEAKIHL DRVGNDGANY VHEAYLMPRL SDEEQKLDIQ 250
    AEINQTLEDL NDSEGMAQLE EQLQYYRALI DKLSAEIERE VKGAGIDGIE 300
    DMEGAAACEL ENSDLESVKC DLETSMKAGL TIHSHLSGIQ REIKYSDSLL 350
    QMKAREYELL AKEFSSLHIS NKDGCQGKEN RGKEAEAPSS NGETPPLTQR 400
    VFNIYTNDTD SDTGISSNHS QDSETTLGDV LLLAT 435
    Length:435
    Mass (Da):49,582
    Last modified:October 1, 2002 - v1
    Checksum:i4F36702F273DEE49
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti370 – 3701S → N in BAC28302. (PubMed:16141072)Curated
    Sequence conflicti409 – 4091T → A in BAC28302. (PubMed:16141072)Curated
    Sequence conflicti429 – 4291D → N in BAC28302. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK033464 mRNA. Translation: BAC28302.1.
    AK041688 mRNA. Translation: BAC31033.1.
    BC028805 mRNA. Translation: AAH28805.1.
    CCDSiCCDS36048.1.
    RefSeqiNP_666352.1. NM_146240.4.
    UniGeneiMm.282672.

    Genome annotation databases

    EnsembliENSMUST00000055355; ENSMUSP00000054767; ENSMUSG00000044921.
    GeneIDi237504.
    KEGGimmu:237504.
    UCSCiuc007gyf.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK033464 mRNA. Translation: BAC28302.1 .
    AK041688 mRNA. Translation: BAC31033.1 .
    BC028805 mRNA. Translation: AAH28805.1 .
    CCDSi CCDS36048.1.
    RefSeqi NP_666352.1. NM_146240.4.
    UniGenei Mm.282672.

    3D structure databases

    ProteinModelPortali Q8K342.
    SMRi Q8K342. Positions 28-117.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q8K342.

    Protocols and materials databases

    DNASUi 237504.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000055355 ; ENSMUSP00000054767 ; ENSMUSG00000044921 .
    GeneIDi 237504.
    KEGGi mmu:237504.
    UCSCi uc007gyf.1. mouse.

    Organism-specific databases

    CTDi 9182.
    MGIi MGI:2384307. Rassf9.

    Phylogenomic databases

    eggNOGi NOG237393.
    GeneTreei ENSGT00510000047164.
    HOGENOMi HOG000065674.
    HOVERGENi HBG053178.
    InParanoidi Q8K342.
    KOi K09856.
    OMAi DHTIHQQ.
    OrthoDBi EOG7MSMNT.
    PhylomeDBi Q8K342.
    TreeFami TF326923.

    Miscellaneous databases

    NextBioi 383390.
    PROi Q8K342.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8K342.
    Genevestigatori Q8K342.

    Family and domain databases

    InterProi IPR000159. Ras-assoc.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view ]
    SMARTi SM00314. RA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54236. SSF54236. 1 hit.
    PROSITEi PS50200. RA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Colon and Thymus.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Mammary gland.

    Entry informationi

    Entry nameiRASF9_MOUSE
    AccessioniPrimary (citable) accession number: Q8K342
    Secondary accession number(s): Q8BZV4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3