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Q8K2I2 (CCHCR_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Coiled-coil alpha-helical rod protein 1
Alternative name(s):
Alpha-helical coiled-coil rod protein
Gene names
Name:Cchcr1
Synonyms:Hcr
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length770 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be a regulator of keratinocyte proliferation or differentiation By similarity.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence caution

The sequence AAH31416.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 770770Coiled-coil alpha-helical rod protein 1
PRO_0000089417

Regions

Coiled coil56 – 289234 Potential
Coiled coil334 – 42087 Potential
Coiled coil476 – 669194 Potential

Experimental info

Sequence conflict7201S → L in AAH31416. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q8K2I2 [UniParc].

Last modified October 3, 2012. Version 3.
Checksum: CAC0D3143E0660C7

FASTA77087,105
        10         20         30         40         50         60 
MLPPSGFAGL VPPSHFQARP LPTLPRMAPT WASDVPLVQS PASQDVLERR LDAQRSTVTT 

        70         80         90        100        110        120 
WGQDFCGDGQ GLGRRGRSLE LGFSSALSQQ AELISRQLQE LRRLEEEVRS LRETSLQQKM 

       130        140        150        160        170        180 
RLETQAVELD ALAVAEKAGQ AEAEGLRTAL AGAEMVRKNL EEAKHKELEE IQSLHQEQLS 

       190        200        210        220        230        240 
SLTQAHQKAL DSLASKAEGL EKSLNSLETK RAGEAKQLAM AQKEADMLRN QLSKTQEELE 

       250        260        270        280        290        300 
AQVTLVESLR KYVGEQVLPE FPSQEWELER KELLDTLKHL KEDRADLQAT VELLQVRVQS 

       310        320        330        340        350        360 
LTHMLALQEE ELTRKIQPLD PLEPEFPKKC RSLLRNWREK VFALMVQLKA QDLQHRDSTS 

       370        380        390        400        410        420 
QLRIQVAELQ EQVTSQSQEQ AILQRALQDK TAQVEVERMS TKSLQMELDQ AQEARRRQEQ 

       430        440        450        460        470        480 
QIASAEEQLK FVVGAMNSTQ AKLQSTMTRM DQAVARIPSL SNRLSYAVRK VHTIKGLMAR 

       490        500        510        520        530        540 
KVALAQLRVE SSPPSEAAPP LDTDLSVELE QLREERNRLD AELQLSAHLI QQEVGRAREQ 

       550        560        570        580        590        600 
GEVERRRLIE VAQQLEQELQ RAQESLASVG QQLEAARRGQ QESTEEAASL RQELTQQQEI 

       610        620        630        640        650        660 
YGQALQEKVA EVETRLREQL SDTKRRLNEA RREQAKAVVS LRQIQHKATQ EKERNQELRR 

       670        680        690        700        710        720 
LQDEARKEEG QRLTRRVQEL ERDKNLMLQR LLAVLPSGVN KKCSPRSVES SSSESPAAAS 

       730        740        750        760        770 
CKESVKGSLT VLLDNLQGLS EAISRDEDIC VEDNQNTKKT KNPPSDPLLS 

« Hide

References

[1]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
[2]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR974473 Genomic DNA. No translation available.
CH466559 Genomic DNA. Translation: EDL23219.1.
BC031416 mRNA. Translation: AAH31416.1. Different initiation.
CCDSCCDS50090.1.
RefSeqNP_666360.2. NM_146248.2.
UniGeneMm.49544.

3D structure databases

ProteinModelPortalQ8K2I2.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ8K2I2.

Proteomic databases

PRIDEQ8K2I2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000045956; ENSMUSP00000046612; ENSMUSG00000040312.
ENSMUST00000164242; ENSMUSP00000132028; ENSMUSG00000040312.
GeneID240084.
KEGGmmu:240084.
UCSCuc008chx.2. mouse.

Organism-specific databases

CTD54535.
MGIMGI:2385321. Cchcr1.

Phylogenomic databases

eggNOGNOG130491.
GeneTreeENSGT00710000106841.
HOGENOMHOG000231221.
HOVERGENHBG048718.
InParanoidQ8K2I2.
KOK16760.
OrthoDBEOG75F4F8.
TreeFamTF336947.

Gene expression databases

ArrayExpressQ8K2I2.
CleanExMM_CCHCR1.
GenevestigatorQ8K2I2.

Family and domain databases

InterProIPR009800. HCR.
[Graphical view]
PANTHERPTHR23161:SF4. PTHR23161:SF4. 1 hit.
PfamPF07111. HCR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSCCHCR1. mouse.
NextBio384437.
PROQ8K2I2.
SOURCESearch...

Entry information

Entry nameCCHCR_MOUSE
AccessionPrimary (citable) accession number: Q8K2I2
Secondary accession number(s): G3UWG0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: October 3, 2012
Last modified: July 9, 2014
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot