Q8K233 (Q8K233_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ace protein EMBL AAH34367.1

Submitted name:
Angiotensin I converting enzyme (Peptidyl-dipeptidase A) 1, isoform CRA_b EMBL EDL34254.1

Gene names

Name:	Ace MGI 87874 EMBL AAH34367.1
ORF Names:	mCG_4821 EMBL EDL34254.1

Organism

Mus musculus (Mouse) EMBL AAH34367.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1015 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	heart contraction Inferred from mutant phenotype PubMed 16585392. Source: MGI kidney development Inferred from mutant phenotype PubMed 17135368. Source: MGI neutrophil mediated immunity Inferred from mutant phenotype PubMed 17082641. Source: MGI positive regulation of systemic arterial blood pressure Inferred from mutant phenotype PubMed 17135368PubMed 9231832. Source: MGI proteolysis Inferred from electronic annotation. Source: InterPro spermatogenesis Inferred from mutant phenotype PubMed 17135368. Source: MGI
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	metallopeptidase activity Inferred from electronic annotation. Source: InterPro peptidase activity Inferred from mutant phenotype PubMed 9231832. Source: MGI peptidyl-dipeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH34367.1

Sequences

	Sequence		Length	Mass (Da)
	Q8K233 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: D097F69585553C27	FASTA	1,015	117,509
	10 20 30 40 50 60 WYESPSFEES LEHIYHQLEP LYLNLHAYVR RALHRRYGDK YVNLRGPIPA HLLGDMWAQS 70 80 90 100 110 120 WENIYDMVVP FPDKPNLDVT STMVQKGWNA THMFRVSEEF FTSLGLSPMP PEFWAESMLE 130 140 150 160 170 180 KPTDGREVVC HASAWDFYNR KDFRIKQCTR VTMEQLATVH HEMGHVQYYL QYKDLHVSLR 190 200 210 220 230 240 RGANPGFHEA IGDVLALSVS TPAHLHKIGL LDHVTNDIES DINYLLKMAL EKIAFLPFGY 250 260 270 280 290 300 LVDQWRWGVF SGRTPPSRYN FDWWYLRTKY QGICPPVARN ETHFDAGAKF HIPNVTPYIR 310 320 330 340 350 360 YFVSFVLQFQ FHQALCKEAG HQGPLHQCDI YQSAQAGAKL KQVLQAGCSR PWQEVLKDLV 370 380 390 400 410 420 GSDALDAKAL LEYFQPVSQW LEEQNQRNGE VLGWPENQWR PPLPDNYPEG IDLETDEAKA 430 440 450 460 470 480 DRFVEEYDRT AQVLLNEYAE ANWQYNTNIT IEGSKILLEK STEVSNHTLK YGTRAKTFDV 490 500 510 520 530 540 SNFQNSSIKR IIKKLQNLDR AVLPPKELEE YNQILLDMET TYSLSNICYT NGTCMPLEPD 550 560 570 580 590 600 LTNMMATSRK YEELLWAWKS WRDKVGRAIL PFFPKYVEFS NKIAKLNGYT DAGDSWRSLY 610 620 630 640 650 660 ESDNLEQDLE KLYQELQPLY LNLHAYVRRS LHRHYGSEYI NLDGPIPAHL LGNMWAQTWS 670 680 690 700 710 720 NIYDLVAPFP SAPNIDATEA MIKQGWTPRR IFKEADNFFT SLGLLPVPPE FWNKSMLEKP 730 740 750 760 770 780 TDGREVVCHP SAWDFYNGKD FRIKQCTSVN MEDLVIAHHE MGHIQYFMQY KDLPVTFREG 790 800 810 820 830 840 ANPGFHEAIG DIMALSVSTP KHLYSLNLLS TEGSGYEYDI NFLMKMALDK IAFIPFSYLI 850 860 870 880 890 900 DQWRWRVFDG SITKENYNQE WWSLRLKYQG LCPPVPRSQG DFDPGSKFHV PANVPYVRYF 910 920 930 940 950 960 VSFIIQFQFH EALCRAAGHT GPLHKCDIYQ SKEAGKLLAD AMKLGYSKPW PEAMKLITGQ 970 980 990 1000 1010 PNMSASAMMN YFKPLTEWLV TENRRHGETL GWPEYNWAPN TGTTPTLPPA PGPSS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL34254.1.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: FVB/N EMBL AAH34367.1. Tissue: Mammary tumor. C3 EMBL AAH34367.1.
[3]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL34254.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC034367 mRNA. Translation: AAH34367.1. CH466558 Genomic DNA. Translation: EDL34254.1.
IPI	IPI00556843.
UniGene	Mm.754.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:87874. Ace.
Phylogenomic databases
HOVERGEN	HBG000264.
InParanoid	Q8K233.
Gene expression databases
Genevestigator	Q8K233.
Family and domain databases
InterPro	IPR001548. Peptidase_M2. [Graphical view]
PANTHER	PTHR10514. PTHR10514. 1 hit.
Pfam	PF01401. Peptidase_M2. 2 hits. [Graphical view]
PRINTS	PR00791. PEPDIPTASEA.
ProtoNet	Search...
Other
ChiTaRS	ACE. mouse.
SOURCE	Search...

Entry information

Entry name

Q8K233_MOUSE

Accession

Primary (citable) accession number: Q8K233

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	May 29, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)