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Q8K220

- Q8K220_MOUSE

UniProt

Q8K220 - Q8K220_MOUSE

Protein
Submitted name:

Relb protein

Gene

Relb

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. protein binding Source: MGI
    3. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. antigen processing and presentation Source: MGI
    2. myeloid dendritic cell differentiation Source: MGI
    3. NIK/NF-kappaB signaling Source: MGI
    4. positive regulation of gene expression Source: MGI
    5. T-helper 1 cell differentiation Source: MGI
    6. T-helper 1 type immune response Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Relb proteinImported
    Submitted name:
    Transcription factor RelBImported
    Gene namesi
    Name:RelbImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:103289. Relb.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: MGI
    2. nucleus Source: MGI

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ8K220.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 RHD (Rel-like) domain.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00500000044765.
    HOGENOMiHOG000148598.
    HOVERGENiHBG017021.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    2.60.40.340. 1 hit.
    InterProiIPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002909. IPT.
    IPR000451. NF_Rel_Dor.
    IPR008967. p53-like_TF_DNA-bd.
    IPR011539. RHD.
    [Graphical view]
    PfamiPF00554. RHD. 1 hit.
    [Graphical view]
    PRINTSiPR00057. NFKBTNSCPFCT.
    SMARTiSM00429. IPT. 1 hit.
    [Graphical view]
    SUPFAMiSSF49417. SSF49417. 1 hit.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS01204. REL_1. 1 hit.
    PS50254. REL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8K220-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSRRAARES APELGALGSS DLSSLSLTVS RTTEIIDEYI KENGFGLDGT    50
    QLSEMPRLVP RGPASLSSVT LGPAAPPPPA TPSWSCTLGR LVSPGPCPRP 100
    YLVITEQPKQ RGMRFRYECE GRSAGSILGE SSTEASKTLP AIELRDCGGL 150
    REVEVTACLV WKDWPHRVHP HSLVGKDCTD GVCRVRLRPH VSPRHSFNNL 200
    GIQCVRKKEI EAAIERKIQL GIDPYNAGSL KNHQEVDMNV VRICFQASYR 250
    DQQGHLHRMD PILSEPVYDK KSTNTSELRI CRINKESGPC TGGEELYLLC 300
    DKVQKEDISV VFSTASWEGR ADFSQADVHR QIAIVFKTPP YEDLEISEPV 350
    TVNVFLQRLT DGVCSEPLPF TYLPRDHDSY GVDKKRKRGL PDVLGELSSS 400
    DPHGIESKRR KKKPVFLDHF LPGHSSGLFL PPSALQPADS DFFPASISLP 450
    GLEPPGGPDL LDDGFAYDPS APTLFTMLDL LPPAPPLASA VVGSGGAGAT 500
    VVESSGPEPL SLDSFAAPGP GDVGTASLVG SNMFPNQYRE AAFGGGLLSP 550
    GPEAT 555
    Length:555
    Mass (Da):59,948
    Last modified:October 1, 2002 - v1
    Checksum:i12642B8A5B9E099A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC149052 Genomic DNA. No translation available.
    BC034523 mRNA. Translation: AAH34523.1.
    RefSeqiNP_001277386.1. NM_001290457.1.
    UniGeneiMm.1741.

    Genome annotation databases

    EnsembliENSMUST00000049912; ENSMUSP00000050166; ENSMUSG00000002983.
    GeneIDi19698.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC149052 Genomic DNA. No translation available.
    BC034523 mRNA. Translation: AAH34523.1 .
    RefSeqi NP_001277386.1. NM_001290457.1.
    UniGenei Mm.1741.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000049912 ; ENSMUSP00000050166 ; ENSMUSG00000002983 .
    GeneIDi 19698.

    Organism-specific databases

    MGIi MGI:103289. Relb.

    Phylogenomic databases

    GeneTreei ENSGT00500000044765.
    HOGENOMi HOG000148598.
    HOVERGENi HBG017021.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8K220.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    2.60.40.340. 1 hit.
    InterProi IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002909. IPT.
    IPR000451. NF_Rel_Dor.
    IPR008967. p53-like_TF_DNA-bd.
    IPR011539. RHD.
    [Graphical view ]
    Pfami PF00554. RHD. 1 hit.
    [Graphical view ]
    PRINTSi PR00057. NFKBTNSCPFCT.
    SMARTi SM00429. IPT. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49417. SSF49417. 1 hit.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS01204. REL_1. 1 hit.
    PS50254. REL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/NImported.
      Tissue: Mammary tumor. Metallothionien-TGF alpha model. 10 month old virgin mouse. Taken by biopsy.Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8K220_MOUSE
    AccessioniPrimary (citable) accession number: Q8K220
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3