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Protein

Protein phosphatase 1 regulatory subunit 11

Gene

Ppp1r11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Inhibitor of protein phosphatase 1.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Protein phosphatase inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase 1 regulatory subunit 11
Alternative name(s):
T-complex testis expressed protein 5
Short name:
Tctex-5
Gene namesi
Name:Ppp1r11
Synonyms:Tctex5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1923747. Ppp1r11.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • nucleus Source: GO_Central
  • protein phosphatase type 1 complex Source: GO_Central
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 131130Protein phosphatase 1 regulatory subunit 11PRO_0000239621Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Modified residuei78 – 781PhosphoserineBy similarity
Modified residuei79 – 791PhosphoserineCombined sources
Modified residuei80 – 801PhosphothreonineCombined sources
Modified residuei82 – 821PhosphoserineCombined sources
Modified residuei114 – 1141PhosphothreonineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ8K1L5.
MaxQBiQ8K1L5.
PaxDbiQ8K1L5.
PeptideAtlasiQ8K1L5.
PRIDEiQ8K1L5.

PTM databases

iPTMnetiQ8K1L5.
PhosphoSiteiQ8K1L5.

Expressioni

Tissue specificityi

Expressed in testis with high level during spermatogenesis.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047202.

Structurei

3D structure databases

ProteinModelPortaliQ8K1L5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi105 – 12824Pro-richAdd
BLAST

Phylogenomic databases

eggNOGiKOG4102. Eukaryota.
ENOG41126IN. LUCA.
HOGENOMiHOG000232107.
HOVERGENiHBG080560.
InParanoidiQ8K1L5.
KOiK17553.
PhylomeDBiQ8K1L5.

Family and domain databases

InterProiIPR011107. PPI_Ypi1.
[Graphical view]
PANTHERiPTHR20835. PTHR20835. 1 hit.
PfamiPF07491. PPI_Ypi1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8K1L5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAETGAGISE TVTETTVTET TVTETTEPEN QSLIMKLRKR KPEKKVEWSS
60 70 80 90 100
DTVDNEHMGR RSSKCCCIYE KPRAFGESST ESDEDEEEGC SHKHCVRGHR
110 120 130
KGRRPTTPAP TPTTPPQPPD PSQPPPGPMQ H
Length:131
Mass (Da):14,544
Last modified:October 1, 2002 - v1
Checksum:i533FCEC7128FA14C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti34 – 341I → T in BAB23986 (PubMed:16141072).Curated
Sequence conflicti123 – 1231Q → K in BAB23986 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005379 mRNA. Translation: BAB23986.1.
AK089107 mRNA. Translation: BAC40754.1.
AK170104 mRNA. Translation: BAE41566.1.
BC027737 mRNA. Translation: AAH27737.1.
CCDSiCCDS28729.1.
RefSeqiNP_083908.1. NM_029632.3.
UniGeneiMm.46176.

Genome annotation databases

GeneIDi76497.
KEGGimmu:76497.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005379 mRNA. Translation: BAB23986.1.
AK089107 mRNA. Translation: BAC40754.1.
AK170104 mRNA. Translation: BAE41566.1.
BC027737 mRNA. Translation: AAH27737.1.
CCDSiCCDS28729.1.
RefSeqiNP_083908.1. NM_029632.3.
UniGeneiMm.46176.

3D structure databases

ProteinModelPortaliQ8K1L5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047202.

PTM databases

iPTMnetiQ8K1L5.
PhosphoSiteiQ8K1L5.

Proteomic databases

EPDiQ8K1L5.
MaxQBiQ8K1L5.
PaxDbiQ8K1L5.
PeptideAtlasiQ8K1L5.
PRIDEiQ8K1L5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi76497.
KEGGimmu:76497.

Organism-specific databases

CTDi6992.
MGIiMGI:1923747. Ppp1r11.

Phylogenomic databases

eggNOGiKOG4102. Eukaryota.
ENOG41126IN. LUCA.
HOGENOMiHOG000232107.
HOVERGENiHBG080560.
InParanoidiQ8K1L5.
KOiK17553.
PhylomeDBiQ8K1L5.

Miscellaneous databases

ChiTaRSiPpp1r11. mouse.
PROiQ8K1L5.
SOURCEiSearch...

Family and domain databases

InterProiIPR011107. PPI_Ypi1.
[Graphical view]
PANTHERiPTHR20835. PTHR20835. 1 hit.
PfamiPF07491. PPI_Ypi1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPP1RB_MOUSE
AccessioniPrimary (citable) accession number: Q8K1L5
Secondary accession number(s): Q9DB02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: October 1, 2002
Last modified: July 6, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.