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Protein

Spindlin-4

Gene

Spin4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Spindlin-4
Gene namesi
Name:Spin4
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2444925. Spin4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 249249Spindlin-4PRO_0000313795Add
BLAST

Proteomic databases

PRIDEiQ8K1L2.

PTM databases

PhosphoSiteiQ8K1L2.

Expressioni

Gene expression databases

BgeeiQ8K1L2.
CleanExiMM_SPIN4.
GenevisibleiQ8K1L2. MM.

Structurei

3D structure databases

ProteinModelPortaliQ8K1L2.
SMRiQ8K1L2. Positions 35-246.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SPIN/STSY family.Curated

Phylogenomic databases

eggNOGiNOG329027.
GeneTreeiENSGT00760000119261.
HOGENOMiHOG000293367.
HOVERGENiHBG000686.
InParanoidiQ8K1L2.
OMAiHGRKDEW.
OrthoDBiEOG7CK37K.
PhylomeDBiQ8K1L2.
TreeFamiTF332665.

Family and domain databases

InterProiIPR003671. SPIN/Ssty.
IPR029578. Spindlin-4.
[Graphical view]
PANTHERiPTHR10405. PTHR10405. 1 hit.
PTHR10405:SF9. PTHR10405:SF9. 1 hit.
PfamiPF02513. Spin-Ssty. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K1L2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPPTVPPTG VDGVSAYLMK KRHTHKKQRR KPTFLTHRNI VGCRIQHGWK
60 70 80 90 100
EGNEPVEQWK GTVLEQVSVK PTLYIIKYDG KDSVYGLELH RDKRVLALEI
110 120 130 140 150
LPERVPSPRI DSRLADSLVG KAVGHVFEGE HGKKDEWKGM VLARAPIMDT
160 170 180 190 200
WFYITYEKDP VLYMYTLLDD YKDGDLRIIP DSNYYFPAAE QEPGEVLDSL
210 220 230 240
VGKQVEHAKD DGSKRTGIFI HQVVAKPSVY FIKFDDDIHI YVYGLVKTP
Length:249
Mass (Da):28,508
Last modified:October 1, 2002 - v1
Checksum:i0B0485959A4A2F10
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti41 – 411V → G in BAC33186 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK036158 mRNA. Translation: BAC29325.1.
AK043030 mRNA. Translation: BAC31440.1.
AK047896 mRNA. Translation: BAC33186.1.
AK147852 mRNA. Translation: BAE28181.1.
AK155170 mRNA. Translation: BAE33091.1.
BX470092 Genomic DNA. Translation: CAM18132.1.
BC027796 mRNA. Translation: AAH27796.1.
CCDSiCCDS30282.1.
RefSeqiNP_848868.1. NM_178753.4.
UniGeneiMm.115205.

Genome annotation databases

EnsembliENSMUST00000096367; ENSMUSP00000094095; ENSMUSG00000071722.
GeneIDi270624.
KEGGimmu:270624.
UCSCiuc009tts.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK036158 mRNA. Translation: BAC29325.1.
AK043030 mRNA. Translation: BAC31440.1.
AK047896 mRNA. Translation: BAC33186.1.
AK147852 mRNA. Translation: BAE28181.1.
AK155170 mRNA. Translation: BAE33091.1.
BX470092 Genomic DNA. Translation: CAM18132.1.
BC027796 mRNA. Translation: AAH27796.1.
CCDSiCCDS30282.1.
RefSeqiNP_848868.1. NM_178753.4.
UniGeneiMm.115205.

3D structure databases

ProteinModelPortaliQ8K1L2.
SMRiQ8K1L2. Positions 35-246.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ8K1L2.

Proteomic databases

PRIDEiQ8K1L2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000096367; ENSMUSP00000094095; ENSMUSG00000071722.
GeneIDi270624.
KEGGimmu:270624.
UCSCiuc009tts.2. mouse.

Organism-specific databases

CTDi139886.
MGIiMGI:2444925. Spin4.

Phylogenomic databases

eggNOGiNOG329027.
GeneTreeiENSGT00760000119261.
HOGENOMiHOG000293367.
HOVERGENiHBG000686.
InParanoidiQ8K1L2.
OMAiHGRKDEW.
OrthoDBiEOG7CK37K.
PhylomeDBiQ8K1L2.
TreeFamiTF332665.

Miscellaneous databases

NextBioi393351.
PROiQ8K1L2.
SOURCEiSearch...

Gene expression databases

BgeeiQ8K1L2.
CleanExiMM_SPIN4.
GenevisibleiQ8K1L2. MM.

Family and domain databases

InterProiIPR003671. SPIN/Ssty.
IPR029578. Spindlin-4.
[Graphical view]
PANTHERiPTHR10405. PTHR10405. 1 hit.
PTHR10405:SF9. PTHR10405:SF9. 1 hit.
PfamiPF02513. Spin-Ssty. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Cerebellum and Head.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Mammary tumor.

Entry informationi

Entry nameiSPIN4_MOUSE
AccessioniPrimary (citable) accession number: Q8K1L2
Secondary accession number(s): Q8BXD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 1, 2002
Last modified: June 24, 2015
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.