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Protein
Submitted name:

Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)

Gene

Bub1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)Imported
Gene namesi
Name:Bub1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1100510. Bub1.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028858.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 182172BUB1 N-terminalInterPro annotationAdd
BLAST
Domaini762 – 1059298Protein kinaseInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1166. Eukaryota.
ENOG410XQ67. LUCA.
HOVERGENiHBG003709.

Family and domain databases

InterProiIPR015661. Bub1/Mad3.
IPR011009. Kinase-like_dom.
IPR013212. Mad3/Bub1_I.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR14030. PTHR14030. 2 hits.
PfamiPF08311. Mad3_BUB1_I. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00777. Mad3_BUB1_I. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51489. BUB1_N. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K1K8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNLENVFRM FEAHMQSYTG NDPLGEWESF IKWVEENFPD NKEYLMTLLE
60 70 80 90 100
HLMKEFLHKK NYHNDSRFIN YCLKFAEYNS DRHQFFEFLY NQGIGTKSSY
110 120 130 140 150
IYMSWAGHLE AQGELQHASA IFQTGIHNEA EPKELLQQQY RLFQARLTGI
160 170 180 190 200
HLPAQATTSE PLHSAQILNQ VMMTNSSPEK NSACVPKSQG SECSGVASST
210 220 230 240 250
CDEKSNIREQ RVIMISKSEC SVSSSVAPKP EAQQVMYCKE KLIRGDSEFS
260 270 280 290 300
FEELRAQKYN QRKKHEQWVS EDRNYMKRKE ANAFEEQLLK QKMDELHKKL
310 320 330 340 350
HQVVELSHKD LPASENRPDV SLVCVGQNTC SQQELRGPSL SSISHQTSES
360 370 380 390 400
SGEKPQEEPS VPLMVNAVNS TLLFPAANLP ALPVPVSGQS LTDSRCVNQS
410 420 430 440 450
VHEFMPQCGP ETKEVCETNK VASINDFHTT PNTSLGMVQG TPCKVQPSPT
460 470 480 490 500
VHTKEALGFI MDMFQAPTLP DISDDKDEWP SLDQNEDAFE AQFQKNAVSS
510 520 530 540 550
GDWGVKKIMT LSSAFPIFED GNKENYGLPQ PKNKPLGART FGERSLSKYS
560 570 580 590 600
SRSNEMPHTD EFMDDSTVCG IRCNKTLAPS PKSIGDFTSA AQLSSTPFHK
610 620 630 640 650
FPADLVQIPE DKENVVATQY THMALDSCKE NIVDLSKGRK LGPIQEKISA
660 670 680 690 700
SLPCPSQPAT GGLFTQEAVF GLEAFKCTGI DHATVEDLSD ANAGLQVECV
710 720 730 740 750
QTLGNVNAPS FTVENPWDDE LILKLLSGLS KPVTSYSNTF EWQSKLPAIK
760 770 780 790 800
TKTEYQLGSL LVYVNHLLGE GAFAQVFEAI HGDVRNAKSE QKCILKVQRP
810 820 830 840 850
ANSWEFYIGM QLMERLKPEV HHMFIKFYSA HLFKNGSILV GELYSYGTLL
860 870 880 890 900
NVINLYKNTS EKVMPQALVL TFAIRMLYMV EQVHSCEIIH GDIKPDNFIL
910 920 930 940 950
GHRFLEQADE DLATGLALID LGQSIDMKLF PKGTVFTGKC ETSGFQCPEM
960 970 980 990 1000
LSNKPWNYQI DYFGVAATIY CMLFGSYMKV KNEGGVWKPE GLFRRLPHLD
1010 1020 1030 1040 1050
MWEEFFHIML NIPDCHNLPS LDFLRQNMKK LLEQQYSNKI KTLRNRLIVM

LSEYKRSRK
Length:1,059
Mass (Da):119,701
Last modified:October 1, 2002 - v1
Checksum:iF28E57563F53CE94
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC029116 mRNA. Translation: AAH29116.1.
AK144213 mRNA. Translation: BAE25776.1.
RefSeqiNP_001106650.1. NM_001113179.1.
UniGeneiMm.2185.

Genome annotation databases

GeneIDi12235.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC029116 mRNA. Translation: AAH29116.1.
AK144213 mRNA. Translation: BAE25776.1.
RefSeqiNP_001106650.1. NM_001113179.1.
UniGeneiMm.2185.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028858.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12235.

Organism-specific databases

CTDi699.
MGIiMGI:1100510. Bub1.

Phylogenomic databases

eggNOGiKOG1166. Eukaryota.
ENOG410XQ67. LUCA.
HOVERGENiHBG003709.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

InterProiIPR015661. Bub1/Mad3.
IPR011009. Kinase-like_dom.
IPR013212. Mad3/Bub1_I.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR14030. PTHR14030. 2 hits.
PfamiPF08311. Mad3_BUB1_I. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00777. Mad3_BUB1_I. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51489. BUB1_N. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8K1K8_MOUSE
AccessioniPrimary (citable) accession number: Q8K1K8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 6, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.