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Protein

COX assembly mitochondrial protein 2 homolog

Gene

Cmc2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be involved in cytochrome c oxidase biogenesis.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
COX assembly mitochondrial protein 2 homolog
Gene namesi
Name:Cmc2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1913781. Cmc2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7979COX assembly mitochondrial protein 2 homologPRO_0000192944Add
BLAST

Proteomic databases

EPDiQ8K199.
MaxQBiQ8K199.
PaxDbiQ8K199.
PRIDEiQ8K199.

PTM databases

PhosphoSiteiQ8K199.

Expressioni

Gene expression databases

BgeeiQ8K199.
CleanExiMM_2310061C15RIK.
ExpressionAtlasiQ8K199. baseline and differential.
GenevisibleiQ8K199. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000120966.

Structurei

3D structure databases

ProteinModelPortaliQ8K199.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CMC family.Curated

Phylogenomic databases

eggNOGiKOG4148. Eukaryota.
ENOG41123JB. LUCA.
GeneTreeiENSGT00390000016908.
HOGENOMiHOG000212591.
HOVERGENiHBG045487.
InParanoidiQ8K199.
KOiK18172.
OMAiQHAQEMK.
OrthoDBiEOG75J0QR.
TreeFamiTF314049.

Family and domain databases

InterProiIPR013892. Cyt_c_biogenesis_Cmc1-like.
[Graphical view]
PfamiPF08583. Cmc1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K199-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPDLSPHLH TEECNVLINL LKECHKNHNI LKFFGHCNDL DREMRKCLKN
60 70
EYSERRTRSR EHGAAMRRRL SDPPEEAGR
Length:79
Mass (Da):9,419
Last modified:October 1, 2002 - v1
Checksum:i27B3EDBAEBB3F54A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002429 mRNA. Translation: BAC24989.1.
AK013475 mRNA. Translation: BAC25407.1.
BC027549 mRNA. Translation: AAH27549.1.
CCDSiCCDS40489.1.
RefSeqiNP_081120.2. NM_026844.3.
XP_006531345.1. XM_006531282.2.
XP_011246787.1. XM_011248485.1.
UniGeneiMm.4011.

Genome annotation databases

EnsembliENSMUST00000148235; ENSMUSP00000120966; ENSMUSG00000014633.
GeneIDi66531.
KEGGimmu:66531.
UCSCiuc009nom.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002429 mRNA. Translation: BAC24989.1.
AK013475 mRNA. Translation: BAC25407.1.
BC027549 mRNA. Translation: AAH27549.1.
CCDSiCCDS40489.1.
RefSeqiNP_081120.2. NM_026844.3.
XP_006531345.1. XM_006531282.2.
XP_011246787.1. XM_011248485.1.
UniGeneiMm.4011.

3D structure databases

ProteinModelPortaliQ8K199.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000120966.

PTM databases

PhosphoSiteiQ8K199.

Proteomic databases

EPDiQ8K199.
MaxQBiQ8K199.
PaxDbiQ8K199.
PRIDEiQ8K199.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000148235; ENSMUSP00000120966; ENSMUSG00000014633.
GeneIDi66531.
KEGGimmu:66531.
UCSCiuc009nom.1. mouse.

Organism-specific databases

CTDi56942.
MGIiMGI:1913781. Cmc2.

Phylogenomic databases

eggNOGiKOG4148. Eukaryota.
ENOG41123JB. LUCA.
GeneTreeiENSGT00390000016908.
HOGENOMiHOG000212591.
HOVERGENiHBG045487.
InParanoidiQ8K199.
KOiK18172.
OMAiQHAQEMK.
OrthoDBiEOG75J0QR.
TreeFamiTF314049.

Miscellaneous databases

NextBioi321952.
PROiQ8K199.
SOURCEiSearch...

Gene expression databases

BgeeiQ8K199.
CleanExiMM_2310061C15RIK.
ExpressionAtlasiQ8K199. baseline and differential.
GenevisibleiQ8K199. MM.

Family and domain databases

InterProiIPR013892. Cyt_c_biogenesis_Cmc1-like.
[Graphical view]
PfamiPF08583. Cmc1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Hippocampus and Kidney.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Mammary gland.

Entry informationi

Entry nameiCOXM2_MOUSE
AccessioniPrimary (citable) accession number: Q8K199
Secondary accession number(s): Q8CEV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: October 1, 2002
Last modified: March 16, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.