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Protein

COX assembly mitochondrial protein 2 homolog

Gene

Cmc2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be involved in cytochrome c oxidase biogenesis.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
COX assembly mitochondrial protein 2 homolog
Gene namesi
Name:Cmc2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1913781. Cmc2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7979COX assembly mitochondrial protein 2 homologPRO_0000192944Add
BLAST

Proteomic databases

EPDiQ8K199.
MaxQBiQ8K199.
PaxDbiQ8K199.
PeptideAtlasiQ8K199.
PRIDEiQ8K199.

PTM databases

iPTMnetiQ8K199.
PhosphoSiteiQ8K199.

Expressioni

Gene expression databases

BgeeiENSMUSG00000014633.
CleanExiMM_2310061C15RIK.
ExpressionAtlasiQ8K199. baseline and differential.
GenevisibleiQ8K199. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000120966.

Structurei

3D structure databases

ProteinModelPortaliQ8K199.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CMC family.Curated

Phylogenomic databases

eggNOGiKOG4148. Eukaryota.
ENOG41123JB. LUCA.
GeneTreeiENSGT00390000016908.
HOGENOMiHOG000212591.
HOVERGENiHBG045487.
InParanoidiQ8K199.
KOiK18172.
OMAiQHAQEMK.
TreeFamiTF314049.

Family and domain databases

InterProiIPR013892. Cyt_c_biogenesis_Cmc1-like.
[Graphical view]
PfamiPF08583. Cmc1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K199-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPDLSPHLH TEECNVLINL LKECHKNHNI LKFFGHCNDL DREMRKCLKN
60 70
EYSERRTRSR EHGAAMRRRL SDPPEEAGR
Length:79
Mass (Da):9,419
Last modified:October 1, 2002 - v1
Checksum:i27B3EDBAEBB3F54A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002429 mRNA. Translation: BAC24989.1.
AK013475 mRNA. Translation: BAC25407.1.
BC027549 mRNA. Translation: AAH27549.1.
CCDSiCCDS40489.1.
RefSeqiNP_081120.2. NM_026844.3.
XP_006531345.1. XM_006531282.2.
XP_011246787.1. XM_011248485.1.
UniGeneiMm.4011.

Genome annotation databases

EnsembliENSMUST00000148235; ENSMUSP00000120966; ENSMUSG00000014633.
GeneIDi66531.
KEGGimmu:66531.
UCSCiuc009nom.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002429 mRNA. Translation: BAC24989.1.
AK013475 mRNA. Translation: BAC25407.1.
BC027549 mRNA. Translation: AAH27549.1.
CCDSiCCDS40489.1.
RefSeqiNP_081120.2. NM_026844.3.
XP_006531345.1. XM_006531282.2.
XP_011246787.1. XM_011248485.1.
UniGeneiMm.4011.

3D structure databases

ProteinModelPortaliQ8K199.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000120966.

PTM databases

iPTMnetiQ8K199.
PhosphoSiteiQ8K199.

Proteomic databases

EPDiQ8K199.
MaxQBiQ8K199.
PaxDbiQ8K199.
PeptideAtlasiQ8K199.
PRIDEiQ8K199.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000148235; ENSMUSP00000120966; ENSMUSG00000014633.
GeneIDi66531.
KEGGimmu:66531.
UCSCiuc009nom.1. mouse.

Organism-specific databases

CTDi56942.
MGIiMGI:1913781. Cmc2.

Phylogenomic databases

eggNOGiKOG4148. Eukaryota.
ENOG41123JB. LUCA.
GeneTreeiENSGT00390000016908.
HOGENOMiHOG000212591.
HOVERGENiHBG045487.
InParanoidiQ8K199.
KOiK18172.
OMAiQHAQEMK.
TreeFamiTF314049.

Miscellaneous databases

PROiQ8K199.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000014633.
CleanExiMM_2310061C15RIK.
ExpressionAtlasiQ8K199. baseline and differential.
GenevisibleiQ8K199. MM.

Family and domain databases

InterProiIPR013892. Cyt_c_biogenesis_Cmc1-like.
[Graphical view]
PfamiPF08583. Cmc1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCOXM2_MOUSE
AccessioniPrimary (citable) accession number: Q8K199
Secondary accession number(s): Q8CEV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.