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Protein

Cortexin-1

Gene

Ctxn1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May mediate extracellular or intracellular signaling of cortical neurons during forebrain development.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Cortexin-1
Gene namesi
Name:Ctxn1
Synonyms:Ctxn
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:88566. Ctxn1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 50HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000795011 – 82Cortexin-1Add BLAST82

Proteomic databases

PaxDbiQ8K129.
PRIDEiQ8K129.

PTM databases

iPTMnetiQ8K129.
PhosphoSitePlusiQ8K129.

Expressioni

Gene expression databases

BgeeiENSMUSG00000048644.
CleanExiMM_CTXN1.
ExpressionAtlasiQ8K129. baseline and differential.
GenevisibleiQ8K129. MM.

Family & Domainsi

Sequence similaritiesi

Belongs to the cortexin family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J3U7. Eukaryota.
ENOG41129SJ. LUCA.
GeneTreeiENSGT00390000018468.
HOGENOMiHOG000273868.
HOVERGENiHBG054879.
InParanoidiQ8K129.
OMAiRAPWRIS.
PhylomeDBiQ8K129.
TreeFamiTF333403.

Family and domain databases

InterProiView protein in InterPro
IPR020066. Cortexin.
PfamiView protein in Pfam
PF11057. Cortexin. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD054489. Cortexin. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K129-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSAWTLSPE PLPPSTGPPV GAGLDVEQRT VFAFVLCLLV VLVLLMVRCV
60 70 80
RILLDPYSRM PASSWTDHKE ALERGQFDYA LV
Length:82
Mass (Da):9,059
Last modified:October 1, 2002 - v1
Checksum:i17B789079CF0E0D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028881 mRNA. Translation: AAH28881.1.
CCDSiCCDS40211.1.
RefSeqiNP_899138.1. NM_183315.2.
UniGeneiMm.34210.

Genome annotation databases

EnsembliENSMUST00000053252; ENSMUSP00000057115; ENSMUSG00000048644.
GeneIDi330695.
KEGGimmu:330695.
UCSCiuc009ktp.2. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCTXN1_MOUSE
AccessioniPrimary (citable) accession number: Q8K129
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: October 1, 2002
Last modified: June 7, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families