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Protein

Cortexin-1

Gene

Ctxn1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May mediate extracellular or intracellular signaling of cortical neurons during forebrain development.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Cortexin-1
Gene namesi
Name:Ctxn1
Synonyms:Ctxn
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:88566. Ctxn1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei30 – 5021HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8282Cortexin-1PRO_0000079501Add
BLAST

Proteomic databases

PaxDbiQ8K129.
PRIDEiQ8K129.

PTM databases

iPTMnetiQ8K129.
PhosphoSiteiQ8K129.

Expressioni

Gene expression databases

BgeeiENSMUSG00000048644.
CleanExiMM_CTXN1.
ExpressionAtlasiQ8K129. baseline and differential.
GenevisibleiQ8K129. MM.

Family & Domainsi

Sequence similaritiesi

Belongs to the cortexin family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J3U7. Eukaryota.
ENOG41129SJ. LUCA.
GeneTreeiENSGT00390000018468.
HOGENOMiHOG000273868.
HOVERGENiHBG054879.
InParanoidiQ8K129.
OMAiMSTTWTL.
PhylomeDBiQ8K129.
TreeFamiTF333403.

Family and domain databases

InterProiIPR020066. Cortexin.
[Graphical view]
PfamiPF11057. Cortexin. 1 hit.
[Graphical view]
ProDomiPD054489. Cortexin. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Q8K129-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSAWTLSPE PLPPSTGPPV GAGLDVEQRT VFAFVLCLLV VLVLLMVRCV
60 70 80
RILLDPYSRM PASSWTDHKE ALERGQFDYA LV
Length:82
Mass (Da):9,059
Last modified:October 1, 2002 - v1
Checksum:i17B789079CF0E0D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028881 mRNA. Translation: AAH28881.1.
CCDSiCCDS40211.1.
RefSeqiNP_899138.1. NM_183315.2.
UniGeneiMm.34210.

Genome annotation databases

EnsembliENSMUST00000053252; ENSMUSP00000057115; ENSMUSG00000048644.
GeneIDi330695.
KEGGimmu:330695.
UCSCiuc009ktp.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028881 mRNA. Translation: AAH28881.1.
CCDSiCCDS40211.1.
RefSeqiNP_899138.1. NM_183315.2.
UniGeneiMm.34210.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ8K129.
PhosphoSiteiQ8K129.

Proteomic databases

PaxDbiQ8K129.
PRIDEiQ8K129.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000053252; ENSMUSP00000057115; ENSMUSG00000048644.
GeneIDi330695.
KEGGimmu:330695.
UCSCiuc009ktp.2. mouse.

Organism-specific databases

CTDi404217.
MGIiMGI:88566. Ctxn1.

Phylogenomic databases

eggNOGiENOG410J3U7. Eukaryota.
ENOG41129SJ. LUCA.
GeneTreeiENSGT00390000018468.
HOGENOMiHOG000273868.
HOVERGENiHBG054879.
InParanoidiQ8K129.
OMAiMSTTWTL.
PhylomeDBiQ8K129.
TreeFamiTF333403.

Miscellaneous databases

ChiTaRSiCtxn1. mouse.
PROiQ8K129.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000048644.
CleanExiMM_CTXN1.
ExpressionAtlasiQ8K129. baseline and differential.
GenevisibleiQ8K129. MM.

Family and domain databases

InterProiIPR020066. Cortexin.
[Graphical view]
PfamiPF11057. Cortexin. 1 hit.
[Graphical view]
ProDomiPD054489. Cortexin. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiCTXN1_MOUSE
AccessioniPrimary (citable) accession number: Q8K129
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.