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Q8K120

- NFAC4_MOUSE

UniProt

Q8K120 - NFAC4_MOUSE

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Protein
Nuclear factor of activated T-cells, cytoplasmic 4
Gene
Nfatc4, Nfat3
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation By similarity. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.By similarity3 Publications

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi430 – 4378 By similarityBy similarity

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. protein binding Source: MGI
  3. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: MGI
  4. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. cellular respiration Source: MGI
  2. cellular response to UV Source: MGI
  3. cellular response to lithium ion Source: MGI
  4. heart development Source: MGI
  5. intrinsic apoptotic signaling pathway in response to DNA damage Source: MGI
  6. muscle cell development Source: MGI
  7. patterning of blood vessels Source: MGI
  8. positive regulation of apoptotic process Source: MGI
  9. positive regulation of apoptotic signaling pathway Source: MGI
  10. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  11. positive regulation of tumor necrosis factor production Source: MGI
  12. regulation of synaptic plasticity Source: Ensembl
  13. regulation of transcription, DNA-templated Source: MGI
  14. smooth muscle cell differentiation Source: MGI
  15. transcription from RNA polymerase II promoter Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Differentiation, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear factor of activated T-cells, cytoplasmic 4
Short name:
NF-ATc4
Short name:
NFATc4
Alternative name(s):
T-cell transcription factor NFAT3
Short name:
NF-AT3
Gene namesi
Name:Nfatc4
Synonyms:Nfat3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:1920431. Nfatc4.

Subcellular locationi

Cytoplasm. Nucleus
Note: Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.

GO - Cellular componenti

  1. cytosol Source: MGI
  2. intermediate filament cytoskeleton Source: Ensembl
  3. nucleus Source: MGI
  4. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 901901Nuclear factor of activated T-cells, cytoplasmic 4
PRO_0000367433Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei168 – 1681Phosphoserine; by MAPK7 and MAPK141 Publication
Modified residuei170 – 1701Phosphoserine; by MAPK7 and MAPK141 Publication
Modified residuei213 – 2131Phosphoserine; by MAPK8 and MAPK9 By similarityBy similarity
Modified residuei217 – 2171Phosphoserine; by MAPK8 and MAPK9 By similarityBy similarity
Modified residuei289 – 2891Phosphoserine; by RPS6KA3 By similarityBy similarity
Modified residuei334 – 3341Phosphoserine; by RPS6KA3 By similarityBy similarity
Modified residuei344 – 3441Phosphoserine By similarity

Post-translational modificationi

Phosphorylated by NFATC-kinases; dephosphorylated by calcineurin. Phosphorylated on Ser-168 and Ser-170 by MTOR, IRAK1, MAPK7 and MAPK14, on Ser-213 and Ser-217 by MAPK8 and MAPK9, and on Ser-289 and Ser-344 by RPS6KA3. Phosphorylated by GSK3B.By similarity1 Publication
Ubiquitinated, leading to its degradation by the proteasome and reduced transcriptional activity. Ubiquitination and reduction in transcriptional activity can be further facilitated through GSK3B-dependent phosphorylation. Polyubiquitin linkage is mainly through 'Lys-48' By similarity.By similarity

Keywords - PTMi

Phosphoprotein, Ubl conjugation

Proteomic databases

PRIDEiQ8K120.

PTM databases

PhosphoSiteiQ8K120.

Expressioni

Tissue specificityi

Expressed in all tissues analyzed including brain, lung, heart, testis and muscle.1 Publication

Gene expression databases

BgeeiQ8K120.
GenevestigatoriQ8K120.

Interactioni

Subunit structurei

Member of the multicomponent NFATC transcription complex that consists of at least two components, a pre-existing cytoplasmic component NFATC2 and an inducible nuclear component NFATC1. Other members such as NFATC4, NFATC3 or members of the activating protein-1 family, MAF, GATA4 and Cbp/p300 can also bind the complex. NFATC proteins bind to DNA as monomers. Interacts with CREBBP, GATA4, IRAK1, MAPK8, MAPK9 and RPS6KA3.By similarity1 Publication

Protein-protein interaction databases

BioGridi215821. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ8K120.
SMRiQ8K120. Positions 405-691.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati213 – 22917SP 1
Add
BLAST
Repeati277 – 29317SP 2; approximate
Add
BLAST
Domaini401 – 582182RHD
Add
BLAST
Domaini586 – 68398IPT/TIG
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni114 – 1196Calcineurin-binding By similarityBy similarity
Regioni213 – 293812 approximate SP repeats
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi268 – 2703Nuclear localization signal
Motifi672 – 6743Nuclear localization signal

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi23 – 327305Pro-rich
Add
BLAST
Compositional biasi692 – 836145Pro-rich
Add
BLAST

Domaini

Rel Similarity Domain (RSD) allows DNA-binding and cooperative interactions with AP1 factors By similarity.By similarity

Sequence similaritiesi

Contains 1 IPT/TIG domain.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG70055.
GeneTreeiENSGT00550000074562.
HOGENOMiHOG000231780.
HOVERGENiHBG104364.
InParanoidiQ3TXW7.
KOiK17334.
OMAiWTPDDPW.
OrthoDBiEOG79PJND.
PhylomeDBiQ8K120.
TreeFamiTF326480.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProiIPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR008366. NFAT.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view]
PANTHERiPTHR12533. PTHR12533. 1 hit.
PfamiPF00554. RHD. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view]
PRINTSiPR01789. NUCFACTORATC.
SMARTiSM00429. IPT. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS50254. REL_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 15 Publications (identifier: Q8K120-1) [UniParc]FASTAAdd to Basket

Also known as: I-IXL

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MGAASCEDEE LEFKLVFGEE KEPPPLGPGG PGEELDSEDT PPCCRLALGE    50
PLPYGAAPIG IPRPPPPRPG MHSPPPRPAP SPGTWESQPA RSVRLGGPGG 100
NAGGAGGGRV LECPSIRITS ISPTPDPPTS LEDTSETWGD GSPRDYPPPE 150
GFGGYREAGG QGGGAFFSPS PGSSSLSSWS FFSDASDEAA LYAACDEVES 200
ELNEAASRFG LSSPLPSPRA SPRPWTPEDP WSLYGPSSGG RAPEDSWLLL 250
SAPGPVPASP RPASPCGKRR YSSSGTPSSA SPALSRRGSL GEEGPEPPPP 300
PPLPLVRDPS SPGPFDYVGA PPTESIPQKT RRTSSEQAVA LPRSEEPPSC 350
NGKLPSGTED SVAAPGALRK EVAGMDYLAV PSPLAWSKAR IGGHSPIFRT 400
SALPPLDWPL PSQYEQLELR IEVQPRAHHR AHYETEGSRG AVKAAPGGHP 450
VVKLLGYSEK PLTLQMFIGT ADERSLRPHA FYQVHRITGK MVATASYEAV 500
VSGTKVLEMT LLPENNMAAN IDCAGILKLR NSDIELRKGE TDIGRKNTRV 550
RLVFRVHVPQ GGGKVVSVQA ASVPIECSQR SAQELPQVET YSPSACSVRG 600
GEELVLTGSN FLPDSKVVFI ERGPDGKLQW EEEAAVNRLQ SSEVTLTLTI 650
PEYSNKRVSR PVQVYFYVSN GRRKRSPTQS FKFLPVVFKE EPLPDSSLRG 700
FPSTSGPPFG PDVDFSPPRP PYPSYPHEDP AYETPYLSEG FGYSTPALYP 750
QTGPPPSYRS GLRMFPETGG TTGCARLPSV SFLPRPFPGD QYGGQGSSFA 800
LGLPFSPPAP FRPPLPSSPP LEDPFHPQSA IHPLPPEGYN EVGPGYTPGE 850
GASEQEKARG GYSSGFRDSV PIQGITLEEV SEIIGRDLSG FPARPGEEPP 900
A 901
Length:901
Mass (Da):95,782
Last modified:March 24, 2009 - v2
Checksum:i5977695F888F6538
GO
Isoform 21 Publication (identifier: Q8K120-2) [UniParc]FASTAAdd to Basket

Also known as: I-IXi

The sequence of this isoform differs from the canonical sequence as follows:
     880-894: VSEIIGRDLSGFPAR → GGCGTGGCECK
     895-901: Missing.

Show »
Length:890
Mass (Da):94,459
Checksum:i1083BBF9972F0742
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei880 – 89415VSEII…GFPAR → GGCGTGGCECK in isoform 2. 1 Publication
VSP_053054Add
BLAST
Alternative sequencei895 – 9017Missing in isoform 2. 1 Publication
VSP_053055

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti135 – 1351S → P in AAH28928. 1 Publication
Sequence conflicti379 – 3802AV → TM in AAG39446. 1 Publication
Sequence conflicti379 – 3802AV → TM in AAF98174. 1 Publication
Sequence conflicti394 – 3952HS → QT in AAG39446. 1 Publication
Sequence conflicti394 – 3952HS → QT in AAF98174. 1 Publication
Sequence conflicti562 – 5621G → S in AAH28928. 1 Publication
Sequence conflicti589 – 5902ET → GD in AAG39446. 1 Publication
Sequence conflicti589 – 5902ET → GD in AAF98174. 1 Publication
Sequence conflicti662 – 6621V → I in AAG39446. 1 Publication
Sequence conflicti662 – 6621V → I in AAF98174. 1 Publication
Sequence conflicti730 – 7301P → L in AAG39446. 1 Publication
Sequence conflicti730 – 7301P → L in AAF98174. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF283284 mRNA. Translation: AAF98174.1.
AF309389, AF309388 Genomic DNA. Translation: AAG39446.1.
EU887656 mRNA. Translation: ACG55676.1.
EU887657 mRNA. Translation: ACG55677.1.
AK159078 mRNA. Translation: BAE34797.1.
CH466535 Genomic DNA. Translation: EDL36234.1.
BC028928 mRNA. Translation: AAH28928.1.
CCDSiCCDS27132.1. [Q8K120-1]
CCDS49500.1. [Q8K120-2]
RefSeqiNP_001161818.1. NM_001168346.1. [Q8K120-2]
NP_076188.3. NM_023699.3. [Q8K120-1]
UniGeneiMm.27908.

Genome annotation databases

EnsembliENSMUST00000024179; ENSMUSP00000024179; ENSMUSG00000023411. [Q8K120-1]
ENSMUST00000172271; ENSMUSP00000132763; ENSMUSG00000023411. [Q8K120-2]
GeneIDi73181.
KEGGimmu:73181.
UCSCiuc007uax.2. mouse. [Q8K120-1]
uc011zlq.1. mouse. [Q8K120-2]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF283284 mRNA. Translation: AAF98174.1 .
AF309389 , AF309388 Genomic DNA. Translation: AAG39446.1 .
EU887656 mRNA. Translation: ACG55676.1 .
EU887657 mRNA. Translation: ACG55677.1 .
AK159078 mRNA. Translation: BAE34797.1 .
CH466535 Genomic DNA. Translation: EDL36234.1 .
BC028928 mRNA. Translation: AAH28928.1 .
CCDSi CCDS27132.1. [Q8K120-1 ]
CCDS49500.1. [Q8K120-2 ]
RefSeqi NP_001161818.1. NM_001168346.1. [Q8K120-2 ]
NP_076188.3. NM_023699.3. [Q8K120-1 ]
UniGenei Mm.27908.

3D structure databases

ProteinModelPortali Q8K120.
SMRi Q8K120. Positions 405-691.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 215821. 2 interactions.

PTM databases

PhosphoSitei Q8K120.

Proteomic databases

PRIDEi Q8K120.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000024179 ; ENSMUSP00000024179 ; ENSMUSG00000023411 . [Q8K120-1 ]
ENSMUST00000172271 ; ENSMUSP00000132763 ; ENSMUSG00000023411 . [Q8K120-2 ]
GeneIDi 73181.
KEGGi mmu:73181.
UCSCi uc007uax.2. mouse. [Q8K120-1 ]
uc011zlq.1. mouse. [Q8K120-2 ]

Organism-specific databases

CTDi 4776.
MGIi MGI:1920431. Nfatc4.

Phylogenomic databases

eggNOGi NOG70055.
GeneTreei ENSGT00550000074562.
HOGENOMi HOG000231780.
HOVERGENi HBG104364.
InParanoidi Q3TXW7.
KOi K17334.
OMAi WTPDDPW.
OrthoDBi EOG79PJND.
PhylomeDBi Q8K120.
TreeFami TF326480.

Miscellaneous databases

NextBioi 337621.
PROi Q8K120.
SOURCEi Search...

Gene expression databases

Bgeei Q8K120.
Genevestigatori Q8K120.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProi IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR008366. NFAT.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view ]
PANTHERi PTHR12533. PTHR12533. 1 hit.
Pfami PF00554. RHD. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view ]
PRINTSi PR01789. NUCFACTORATC.
SMARTi SM00429. IPT. 1 hit.
[Graphical view ]
SUPFAMi SSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEi PS50254. REL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Evolutionary relationships among Rel domains indicate functional diversification by recombination."
    Graef I.A., Gastier J.M., Francke U., Crabtree G.R.
    Proc. Natl. Acad. Sci. U.S.A. 98:5740-5745(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1).
    Strain: 129/SvEv.
  2. "Alternative splicing and expression of human and mouse NFAT genes."
    Vihma H., Pruunsild P., Timmusk T.
    Genomics 92:279-291(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), TISSUE SPECIFICITY.
    Strain: C57BL/6.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Rathke gland.
  4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Mammary tumor.
  6. "A calcineurin-dependent transcriptional pathway for cardiac hypertrophy."
    Molkentin J.D., Lu J.-R., Antos C.L., Markham B., Richardson J., Robbins J., Grant S.R., Olson E.N.
    Cell 93:215-228(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH GATA4.
  7. "Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition."
    Yang X.Y., Yang T.T.C., Schubert W., Factor S.M., Chow C.-W.
    Dev. Biol. 303:825-837(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  8. "Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS."
    Luoma J.I., Zirpel L.
    J. Neurosci. 28:3159-3169(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  9. "The interleukin-1 receptor associated kinase 1 contributes to the regulation of NFAT."
    Wang D., Fasciano S., Li L.
    Mol. Immunol. 45:3902-3908(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT SER-168 AND SER-170.

Entry informationi

Entry nameiNFAC4_MOUSE
AccessioniPrimary (citable) accession number: Q8K120
Secondary accession number(s): B5B2X2, Q3TXW7, Q9EP91
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: March 24, 2009
Last modified: July 9, 2014
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi