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Protein
Submitted name:

PMS1 homolog 1, mismatch repair system component

Gene

Pms1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi558 – 626HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

  • mismatch repair Source: MGI
  • response to drug Source: Ensembl

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PMS1 homolog 1, mismatch repair system componentImported
Submitted name:
Postmeiotic segregation increased 1 (S. cerevisiae)Imported
Gene namesi
Name:Pms1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1202302. Pms1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000026098.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027267.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini558 – 626HMG boxInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili608 – 635Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1978. Eukaryota.
COG0323. LUCA.
GeneTreeiENSGT00530000063289.
HOGENOMiHOG000039972.
HOVERGENiHBG031886.
KOiK10864.
OMAiHKLPAEP.
OrthoDBiEOG091G01Z9.
TreeFamiTF300711.

Family and domain databases

CDDicd00075. HATPase_c. 1 hit.
Gene3Di1.10.30.10. 1 hit.
3.30.230.10. 1 hit.
3.30.565.10. 1 hit.
InterProiView protein in InterPro
IPR013507. DNA_mismatch_repair_C.
IPR014762. DNA_mismatch_repair_CS.
IPR002099. DNA_mismatch_repair_fam.
IPR003594. HATPase_C.
IPR036890. HATPase_C_sf.
IPR009071. HMG_box_dom.
IPR036910. HMG_box_dom_sf.
IPR031263. PMS1_hom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
PANTHERiPTHR10073:SF43. PTHR10073:SF43. 1 hit.
PfamiView protein in Pfam
PF01119. DNA_mis_repair. 1 hit.
PF00505. HMG_box. 1 hit.
SMARTiView protein in SMART
SM01340. DNA_mis_repair. 1 hit.
SM00398. HMG. 1 hit.
SUPFAMiSSF47095. SSF47095. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR00585. mutl. 1 hit.
PROSITEiView protein in PROSITE
PS00058. DNA_MISMATCH_REPAIR_1. 1 hit.
PS50118. HMG_BOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K119-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQLPAATVR LLSSSQTITS VVSVVKELIE NSLDAGATSI EVKLENYGFD
60 70 80 90 100
KIEIRDNGEG IKAVDVPVMA VKYYTSKISS HEDLGNLTTY GFRGEALGSI
110 120 130 140 150
CNVAEVVVTT RTSADDFSTQ YVLDGSGHIL SQKPSHLGQG TTVTALKLFK
160 170 180 190 200
NLPVRKQFYS TAKKCKDELK NVQDLLISYG VLKPDVRITF VHNKAVIWQK
210 220 230 240 250
SRVPDHRMAL MSVLGTAVMG NMESVEQHCE QSQIYLSGFF PKHDADHNST
260 270 280 290 300
SLSTPERSFI FINSRPVHQK DILKLIRRYY NLKCLKESTR LYPIFFLKID
310 320 330 340 350
VPSAEVDINL TPDKSQVLLQ NKESVLIALE NLMMTCYGPL PTTESSENNR
360 370 380 390 400
VDISSANMVV SQTAETDVLF NKMESFGNNY PNADTSAIHF QKDESRKNID
410 420 430 440 450
HHLNEQINIG NYFDGHFSGD INKDTFQNIP MNNLSSETNQ SNHSETHSVG
460 470 480 490 500
SMEHIQGENG RNGTGGSGGD GRETLPEKAL EICADDWSKG NLCNSMGENI
510 520 530 540 550
EPVKILVPQK SLSCKVTSSH PRLEPETLSD GPCSRTSDVI HNRSGRLTAY
560 570 580 590 600
DLISSRAVKK PMSASALFIQ DHRTQFLTEN PKTGLEDATE QIKARWETLS
610 620 630 640 650
EEEKHKYEEK AKKDLERYNN QMKKAIEQET QVSLKDGRKK RATSSWGWTQ
660 670 680 690 700
KHKVKDSSNQ PKLDELFQSQ NEKKKSENIK ITEIPFSMEN LKANLKKQKE
710 720 730 740 750
VDLEEKDEIY LIHSLKFPDS WLVTSRADVM LLNPYRVEEA LLFKRLLENH
760 770 780 790 800
KLLAEPLEKP IILTESLLNG SHYLEVLYKM STVEERGSGS AYLCDPRLTA
810 820 830 840 850
NGFKIRLTPG VSSTENYLEI EGMAQCLPFY GIMDLKEILN AIVNKNAKEI
860 870 880 890 900
YECRPRKVIN YLEGEAVRLS RQLPMYLPRE DVQDLIYRMK HQFGKEIKGC
910
VHGRPFFHHL THLPGTS
Length:917
Mass (Da):103,595
Last modified:October 1, 2002 - v1
Checksum:i042C9FC500EE339F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129288 Genomic DNA. No translation available.
AC153650 Genomic DNA. No translation available.
BC028939 mRNA. Translation: AAH28939.1.
RefSeqiNP_705784.1. NM_153556.2.
XP_006496001.1. XM_006495938.3.
XP_006496002.1. XM_006495939.3.
XP_006496004.1. XM_006495941.3.
XP_006496005.1. XM_006495942.3.
XP_011236799.1. XM_011238497.2.
UniGeneiMm.60499.

Genome annotation databases

EnsembliENSMUST00000027267; ENSMUSP00000027267; ENSMUSG00000026098.
GeneIDi227099.
KEGGimmu:227099.
UCSCiuc007ayv.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8K119_MOUSE
AccessioniPrimary (citable) accession number: Q8K119
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: October 25, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported