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Protein
Submitted name:

Postmeiotic segregation increased 1 (S. cerevisiae)

Gene

Pms1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATPase activity Source: GO_Central
  2. ATP binding Source: InterPro
  3. mismatched DNA binding Source: InterPro
  4. single-stranded DNA binding Source: GO_Central

GO - Biological processi

  1. mismatch repair Source: MGI
  2. response to drug Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Postmeiotic segregation increased 1 (S. cerevisiae)Imported
Submitted name:
Protein Pms1Imported
Gene namesi
Name:Pms1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1202302. Pms1.

Subcellular locationi

GO - Cellular componenti

  1. MutLalpha complex Source: GO_Central
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiQ8K119.
PRIDEiQ8K119.

PTM databases

PhosphoSiteiQ8K119.

Expressioni

Gene expression databases

BgeeiQ8K119.
ExpressionAtlasiQ8K119. baseline and differential.
GenevestigatoriQ8K119.

Structurei

3D structure databases

ProteinModelPortaliQ8K119.
SMRiQ8K119. Positions 1-334, 555-636.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063289.
HOGENOMiHOG000039972.
HOVERGENiHBG031886.
InParanoidiQ8K119.
KOiK10864.
OMAiHKLPAEP.
OrthoDBiEOG7S4X59.
PhylomeDBiQ8K119.
TreeFamiTF300711.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
3.30.230.10. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR013507. DNA_mismatch_repair_C.
IPR014762. DNA_mismatch_repair_CS.
IPR002099. DNA_mismatch_repair_fam.
IPR003594. HATPase_C.
IPR009071. HMG_box_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
PfamiPF01119. DNA_mis_repair. 1 hit.
PF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
SM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR00585. mutl. 1 hit.
PROSITEiPS00058. DNA_MISMATCH_REPAIR_1. 1 hit.
PS50118. HMG_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K119-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQLPAATVR LLSSSQTITS VVSVVKELIE NSLDAGATSI EVKLENYGFD
60 70 80 90 100
KIEIRDNGEG IKAVDVPVMA VKYYTSKISS HEDLGNLTTY GFRGEALGSI
110 120 130 140 150
CNVAEVVVTT RTSADDFSTQ YVLDGSGHIL SQKPSHLGQG TTVTALKLFK
160 170 180 190 200
NLPVRKQFYS TAKKCKDELK NVQDLLISYG VLKPDVRITF VHNKAVIWQK
210 220 230 240 250
SRVPDHRMAL MSVLGTAVMG NMESVEQHCE QSQIYLSGFF PKHDADHNST
260 270 280 290 300
SLSTPERSFI FINSRPVHQK DILKLIRRYY NLKCLKESTR LYPIFFLKID
310 320 330 340 350
VPSAEVDINL TPDKSQVLLQ NKESVLIALE NLMMTCYGPL PTTESSENNR
360 370 380 390 400
VDISSANMVV SQTAETDVLF NKMESFGNNY PNADTSAIHF QKDESRKNID
410 420 430 440 450
HHLNEQINIG NYFDGHFSGD INKDTFQNIP MNNLSSETNQ SNHSETHSVG
460 470 480 490 500
SMEHIQGENG RNGTGGSGGD GRETLPEKAL EICADDWSKG NLCNSMGENI
510 520 530 540 550
EPVKILVPQK SLSCKVTSSH PRLEPETLSD GPCSRTSDVI HNRSGRLTAY
560 570 580 590 600
DLISSRAVKK PMSASALFIQ DHRTQFLTEN PKTGLEDATE QIKARWETLS
610 620 630 640 650
EEEKHKYEEK AKKDLERYNN QMKKAIEQET QVSLKDGRKK RATSSWGWTQ
660 670 680 690 700
KHKVKDSSNQ PKLDELFQSQ NEKKKSENIK ITEIPFSMEN LKANLKKQKE
710 720 730 740 750
VDLEEKDEIY LIHSLKFPDS WLVTSRADVM LLNPYRVEEA LLFKRLLENH
760 770 780 790 800
KLLAEPLEKP IILTESLLNG SHYLEVLYKM STVEERGSGS AYLCDPRLTA
810 820 830 840 850
NGFKIRLTPG VSSTENYLEI EGMAQCLPFY GIMDLKEILN AIVNKNAKEI
860 870 880 890 900
YECRPRKVIN YLEGEAVRLS RQLPMYLPRE DVQDLIYRMK HQFGKEIKGC
910
VHGRPFFHHL THLPGTS
Length:917
Mass (Da):103,595
Last modified:October 1, 2002 - v1
Checksum:i042C9FC500EE339F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129288 Genomic DNA. No translation available.
AC153650 Genomic DNA. No translation available.
BC028939 mRNA. Translation: AAH28939.1.
RefSeqiNP_705784.1. NM_153556.1.
XP_006496001.1. XM_006495938.2.
XP_006496002.1. XM_006495939.2.
XP_006496004.1. XM_006495941.2.
XP_006496005.1. XM_006495942.2.
UniGeneiMm.60499.

Genome annotation databases

EnsembliENSMUST00000027267; ENSMUSP00000027267; ENSMUSG00000026098.
GeneIDi227099.
KEGGimmu:227099.
UCSCiuc007ayv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129288 Genomic DNA. No translation available.
AC153650 Genomic DNA. No translation available.
BC028939 mRNA. Translation: AAH28939.1.
RefSeqiNP_705784.1. NM_153556.1.
XP_006496001.1. XM_006495938.2.
XP_006496002.1. XM_006495939.2.
XP_006496004.1. XM_006495941.2.
XP_006496005.1. XM_006495942.2.
UniGeneiMm.60499.

3D structure databases

ProteinModelPortaliQ8K119.
SMRiQ8K119. Positions 1-334, 555-636.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ8K119.

Proteomic databases

MaxQBiQ8K119.
PRIDEiQ8K119.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000027267; ENSMUSP00000027267; ENSMUSG00000026098.
GeneIDi227099.
KEGGimmu:227099.
UCSCiuc007ayv.2. mouse.

Organism-specific databases

CTDi5378.
MGIiMGI:1202302. Pms1.

Phylogenomic databases

GeneTreeiENSGT00530000063289.
HOGENOMiHOG000039972.
HOVERGENiHBG031886.
InParanoidiQ8K119.
KOiK10864.
OMAiHKLPAEP.
OrthoDBiEOG7S4X59.
PhylomeDBiQ8K119.
TreeFamiTF300711.

Miscellaneous databases

NextBioi378474.
PROiQ8K119.
SOURCEiSearch...

Gene expression databases

BgeeiQ8K119.
ExpressionAtlasiQ8K119. baseline and differential.
GenevestigatoriQ8K119.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
3.30.230.10. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR013507. DNA_mismatch_repair_C.
IPR014762. DNA_mismatch_repair_CS.
IPR002099. DNA_mismatch_repair_fam.
IPR003594. HATPase_C.
IPR009071. HMG_box_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
PfamiPF01119. DNA_mis_repair. 1 hit.
PF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
SM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR00585. mutl. 1 hit.
PROSITEiPS00058. DNA_MISMATCH_REPAIR_1. 1 hit.
PS50118. HMG_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EyeImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8K119_MOUSE
AccessioniPrimary (citable) accession number: Q8K119
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: April 1, 2015
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.