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Q8K0Q7 (Q8K0Q7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Ulk1 EMBL AAH30850.1 MGI 1270126
OrganismMus musculus (Mouse) EMBL AAH30850.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length327 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processRas protein signal transduction

Inferred from direct assay PubMed 15014045. Source: MGI

axon extension

Inferred from mutant phenotype PubMed 17389358. Source: MGI

axonogenesis

Inferred from direct assay PubMed 15014045. Source: MGI

cerebellar granule cell differentiation

Inferred from mutant phenotype PubMed 10624947. Source: MGI

negative regulation of collateral sprouting

Inferred from mutant phenotype PubMed 17389358. Source: MGI

neuron projection development

Inferred from mutant phenotype PubMed 10624947. Source: MGI

neuron projection regeneration

Inferred from electronic annotation. Source: Ensembl

positive regulation of macroautophagy

Inferred from electronic annotation. Source: Ensembl

protein autophosphorylation

Inferred from direct assay PubMed 10624947PubMed 9600096. Source: MGI

protein localization

Inferred from electronic annotation. Source: Ensembl

radial glia guided migration of cerebellar granule cell

Inferred from mutant phenotype PubMed 10624947. Source: MGI

receptor internalization

Inferred from mutant phenotype PubMed 17389358. Source: MGI

regulation of neurotrophin TRK receptor signaling pathway

Inferred from mutant phenotype PubMed 17389358. Source: MGI

   Cellular_componentautophagic vacuole

Inferred from electronic annotation. Source: Ensembl

cytoplasm

Inferred from direct assay PubMed 10624947. Source: MGI

cytoplasmic vesicle membrane

Inferred from direct assay PubMed 15014045. Source: MGI

membrane

Inferred from direct assay PubMed 15014045. Source: MGI

neuron projection

Inferred from direct assay PubMed 10624947PubMed 15014045. Source: MGI

neuronal cell body

Inferred from direct assay PubMed 10624947. Source: MGI

pre-autophagosomal structure

Inferred from direct assay PubMed 21220506. Source: MGI

   Molecular_functionprotein kinase activity

Inferred from direct assay PubMed 10624947PubMed 9600096. Source: MGI

protein serine/threonine kinase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAH30850.1

Sequences

Sequence LengthMass (Da)Tools
Q8K0Q7 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: C991072DB0B5A090

FASTA32734,727
        10         20         30         40         50         60 
EIAPSAGFGG TLHPGARGGG ASSPAPVVFT VGSPPSGATP PQSTRTRMFS VGSSSSLGST 

        70         80         90        100        110        120 
GSSSARHLVP GACGEAPELS APGHCCSLAD PLAANLEGAV TFEAPDLPEE TLMEQEHTET 

       130        140        150        160        170        180 
LHSLRFTLAF AQQVLEIAAL KGSASEAAGG PEYQLQESVV ADQISQLSRE WGFAEQLVLY 

       190        200        210        220        230        240 
LKVAELLSSG LQTAIDQIRA GKLCLSSTVK QVVRRLNELY KASVVSCQGL SLRLQRFFLD 

       250        260        270        280        290        300 
KQRLLDGIHG VTAERLILSH AVQMVQSAAL DEMFQHREGC VPRYHKALLL LEGLQHTLTD 

       310        320 
QADIENIAKC KLCIERRLSA LLSGVYA 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N EMBL AAH30850.1.
Tissue: Salivary gland EMBL AAH30850.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC030850 mRNA. Translation: AAH30850.1.
UniGeneMm.271898.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000108029.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:1270126. Ulk1.

Phylogenomic databases

HOVERGENHBG086929.
InParanoidQ8K0Q7.

Gene expression databases

ArrayExpressQ8K0Q7.
BgeeQ8K0Q7.
GenevestigatorQ8K0Q7.

Family and domain databases

InterProIPR022708. Ser/Thr_kinase_C.
[Graphical view]
PfamPF12063. DUF3543. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ8K0Q7_MOUSE
AccessionPrimary (citable) accession number: Q8K0Q7
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)