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Q8K0J4

- Q8K0J4_MOUSE

UniProt

Q8K0J4 - Q8K0J4_MOUSE

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Protein
Submitted name: Epidermal growth factor-containing fibulin-like extracellular matrix protein 1
Gene
Efemp1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. epidermal growth factor-activated receptor activity Source: Ensembl

GO - Biological processi

  1. negative regulation of chondrocyte differentiation Source: Ensembl
  2. regulation of transcription, DNA-templated Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Epidermal growth factor-containing fibulin-like extracellular matrix protein 1Imported
Gene namesi
Name:Efemp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1339998. Efemp1.

Subcellular locationi

GO - Cellular componenti

  1. extracellular matrix Source: Ensembl
  2. extracellular space Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotations

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Proteomic databases

PRIDEiQ8K0J4.

Expressioni

Gene expression databases

ArrayExpressiQ8K0J4.
BgeeiQ8K0J4.
GenevestigatoriQ8K0J4.

Structurei

3D structure databases

ProteinModelPortaliQ8K0J4.

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotations, RepeatSAAS annotations

Phylogenomic databases

HOVERGENiHBG051560.
InParanoidiQ8K0J4.

Family and domain databases

InterProiIPR026823. cEGF.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
[Graphical view]
PfamiPF12662. cEGF. 2 hits.
PF07645. EGF_CA. 2 hits.
[Graphical view]
SMARTiSM00179. EGF_CA. 4 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 4 hits.
PS01186. EGF_2. 4 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K0J4-1 [UniParc]FASTAAdd to Basket

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MATSGVVPGG GFMASATAVA GPEVQTGRNN FVIRRNPADP QRIPSNPSHR    50
IQCAAGYEQS EHNVCQDIDE CTSGTHNCRT DQVCINLRGS FTCQCLPGYQ 100
KRGEQCVDID ECTVPPYCHQ RCVNTPGSFY CQCSPGFQLA ANNYTCVDIN 150
ECDASNQCAQ QCYNILGSFI CQCNQGYELS SDRLNCEDID ECRTSSYLCQ 200
YQCVNEPGKF SCMCPQGYEV VRSRTCQDIN ECETTNECRE DEMCWNYHGG 250
FRCYPRNPCQ DHYVLTSENR CVCPVSNTMC RELPQSIVYK YMSIRSDRSV 300
PSDIFQIQAT MIYANTINTF RIKSGNENGE FYLRQTSPVS AMLVLVKSLS 350
GPREYIVDLE MLTVSSIGTF RTSSVLRLTI IVGPFSF 387
Length:387
Mass (Da):43,335
Last modified:October 1, 2002 - v1
Checksum:iEE88DC9D1422C1C7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC031184 mRNA. Translation: AAH31184.1.
UniGeneiMm.44176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC031184 mRNA. Translation: AAH31184.1 .
UniGenei Mm.44176.

3D structure databases

ProteinModelPortali Q8K0J4.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q8K0J4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1339998. Efemp1.

Phylogenomic databases

HOVERGENi HBG051560.
InParanoidi Q8K0J4.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q8K0J4.
Bgeei Q8K0J4.
Genevestigatori Q8K0J4.

Family and domain databases

InterProi IPR026823. cEGF.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
[Graphical view ]
Pfami PF12662. cEGF. 2 hits.
PF07645. EGF_CA. 2 hits.
[Graphical view ]
SMARTi SM00179. EGF_CA. 4 hits.
[Graphical view ]
SUPFAMi SSF57184. SSF57184. 1 hit.
PROSITEi PS00010. ASX_HYDROXYL. 4 hits.
PS01186. EGF_2. 4 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: ColonImported.

Entry informationi

Entry nameiQ8K0J4_MOUSE
AccessioniPrimary (citable) accession number: Q8K0J4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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