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Q8K0J4

- Q8K0J4_MOUSE

UniProt

Q8K0J4 - Q8K0J4_MOUSE

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Protein
Submitted name:

Epidermal growth factor-containing fibulin-like extracellular matrix protein 1

Gene

Efemp1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. epidermal growth factor-activated receptor activity Source: Ensembl

GO - Biological processi

  1. negative regulation of chondrocyte differentiation Source: Ensembl
  2. regulation of transcription, DNA-templated Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Epidermal growth factor-containing fibulin-like extracellular matrix protein 1Imported
Gene namesi
Name:Efemp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1339998. Efemp1.

Subcellular locationi

GO - Cellular componenti

  1. extracellular matrix Source: Ensembl
  2. extracellular space Source: Ensembl
  3. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PRIDEiQ8K0J4.

Expressioni

Gene expression databases

BgeeiQ8K0J4.
ExpressionAtlasiQ8K0J4. baseline and differential.
GenevestigatoriQ8K0J4.

Structurei

3D structure databases

ProteinModelPortaliQ8K0J4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

HOVERGENiHBG051560.

Family and domain databases

InterProiIPR026823. cEGF.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
[Graphical view]
PfamiPF12662. cEGF. 2 hits.
PF07645. EGF_CA. 2 hits.
[Graphical view]
SMARTiSM00179. EGF_CA. 4 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 4 hits.
PS01186. EGF_2. 4 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K0J4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATSGVVPGG GFMASATAVA GPEVQTGRNN FVIRRNPADP QRIPSNPSHR
60 70 80 90 100
IQCAAGYEQS EHNVCQDIDE CTSGTHNCRT DQVCINLRGS FTCQCLPGYQ
110 120 130 140 150
KRGEQCVDID ECTVPPYCHQ RCVNTPGSFY CQCSPGFQLA ANNYTCVDIN
160 170 180 190 200
ECDASNQCAQ QCYNILGSFI CQCNQGYELS SDRLNCEDID ECRTSSYLCQ
210 220 230 240 250
YQCVNEPGKF SCMCPQGYEV VRSRTCQDIN ECETTNECRE DEMCWNYHGG
260 270 280 290 300
FRCYPRNPCQ DHYVLTSENR CVCPVSNTMC RELPQSIVYK YMSIRSDRSV
310 320 330 340 350
PSDIFQIQAT MIYANTINTF RIKSGNENGE FYLRQTSPVS AMLVLVKSLS
360 370 380
GPREYIVDLE MLTVSSIGTF RTSSVLRLTI IVGPFSF
Length:387
Mass (Da):43,335
Last modified:October 1, 2002 - v1
Checksum:iEE88DC9D1422C1C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC031184 mRNA. Translation: AAH31184.1.
UniGeneiMm.44176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC031184 mRNA. Translation: AAH31184.1 .
UniGenei Mm.44176.

3D structure databases

ProteinModelPortali Q8K0J4.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q8K0J4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1339998. Efemp1.

Phylogenomic databases

HOVERGENi HBG051560.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q8K0J4.
ExpressionAtlasi Q8K0J4. baseline and differential.
Genevestigatori Q8K0J4.

Family and domain databases

InterProi IPR026823. cEGF.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
[Graphical view ]
Pfami PF12662. cEGF. 2 hits.
PF07645. EGF_CA. 2 hits.
[Graphical view ]
SMARTi SM00179. EGF_CA. 4 hits.
[Graphical view ]
SUPFAMi SSF57184. SSF57184. 1 hit.
PROSITEi PS00010. ASX_HYDROXYL. 4 hits.
PS01186. EGF_2. 4 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: ColonImported.

Entry informationi

Entry nameiQ8K0J4_MOUSE
AccessioniPrimary (citable) accession number: Q8K0J4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: November 26, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)