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Q8K0J4

- Q8K0J4_MOUSE

UniProt

Q8K0J4 - Q8K0J4_MOUSE

Protein
Submitted name:

Epidermal growth factor-containing fibulin-like extracellular matrix protein 1

Gene

Efemp1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. epidermal growth factor-activated receptor activity Source: Ensembl

    GO - Biological processi

    1. negative regulation of chondrocyte differentiation Source: Ensembl
    2. regulation of transcription, DNA-templated Source: Ensembl

    Keywords - Ligandi

    CalciumSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Epidermal growth factor-containing fibulin-like extracellular matrix protein 1Imported
    Gene namesi
    Name:Efemp1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1339998. Efemp1.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular matrix Source: Ensembl
    2. extracellular space Source: Ensembl

    Keywords - Cellular componenti

    SecretedSAAS annotation

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Proteomic databases

    PRIDEiQ8K0J4.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8K0J4.
    BgeeiQ8K0J4.
    GenevestigatoriQ8K0J4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K0J4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    EGF-like domainUniRule annotationSAAS annotation, RepeatSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG051560.
    InParanoidiQ8K0J4.

    Family and domain databases

    InterProiIPR026823. cEGF.
    IPR000742. EG-like_dom.
    IPR001881. EGF-like_Ca-bd_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR018097. EGF_Ca-bd_CS.
    IPR009030. Growth_fac_rcpt_N_dom.
    [Graphical view]
    PfamiPF12662. cEGF. 2 hits.
    PF07645. EGF_CA. 2 hits.
    [Graphical view]
    SMARTiSM00179. EGF_CA. 4 hits.
    [Graphical view]
    SUPFAMiSSF57184. SSF57184. 1 hit.
    PROSITEiPS00010. ASX_HYDROXYL. 4 hits.
    PS01186. EGF_2. 4 hits.
    PS50026. EGF_3. 4 hits.
    PS01187. EGF_CA. 5 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8K0J4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATSGVVPGG GFMASATAVA GPEVQTGRNN FVIRRNPADP QRIPSNPSHR    50
    IQCAAGYEQS EHNVCQDIDE CTSGTHNCRT DQVCINLRGS FTCQCLPGYQ 100
    KRGEQCVDID ECTVPPYCHQ RCVNTPGSFY CQCSPGFQLA ANNYTCVDIN 150
    ECDASNQCAQ QCYNILGSFI CQCNQGYELS SDRLNCEDID ECRTSSYLCQ 200
    YQCVNEPGKF SCMCPQGYEV VRSRTCQDIN ECETTNECRE DEMCWNYHGG 250
    FRCYPRNPCQ DHYVLTSENR CVCPVSNTMC RELPQSIVYK YMSIRSDRSV 300
    PSDIFQIQAT MIYANTINTF RIKSGNENGE FYLRQTSPVS AMLVLVKSLS 350
    GPREYIVDLE MLTVSSIGTF RTSSVLRLTI IVGPFSF 387
    Length:387
    Mass (Da):43,335
    Last modified:October 1, 2002 - v1
    Checksum:iEE88DC9D1422C1C7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC031184 mRNA. Translation: AAH31184.1.
    UniGeneiMm.44176.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC031184 mRNA. Translation: AAH31184.1 .
    UniGenei Mm.44176.

    3D structure databases

    ProteinModelPortali Q8K0J4.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q8K0J4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1339998. Efemp1.

    Phylogenomic databases

    HOVERGENi HBG051560.
    InParanoidi Q8K0J4.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8K0J4.
    Bgeei Q8K0J4.
    Genevestigatori Q8K0J4.

    Family and domain databases

    InterProi IPR026823. cEGF.
    IPR000742. EG-like_dom.
    IPR001881. EGF-like_Ca-bd_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR018097. EGF_Ca-bd_CS.
    IPR009030. Growth_fac_rcpt_N_dom.
    [Graphical view ]
    Pfami PF12662. cEGF. 2 hits.
    PF07645. EGF_CA. 2 hits.
    [Graphical view ]
    SMARTi SM00179. EGF_CA. 4 hits.
    [Graphical view ]
    SUPFAMi SSF57184. SSF57184. 1 hit.
    PROSITEi PS00010. ASX_HYDROXYL. 4 hits.
    PS01186. EGF_2. 4 hits.
    PS50026. EGF_3. 4 hits.
    PS01187. EGF_CA. 5 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/NImported.
      Tissue: ColonImported.

    Entry informationi

    Entry nameiQ8K0J4_MOUSE
    AccessioniPrimary (citable) accession number: Q8K0J4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)