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Q8K0E7 (SERC2_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine incorporator 2
Alternative name(s):
Tumor differentially expressed protein 2-like
Gene names
Name:Serinc2
Synonyms:Tde2l
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the TDE1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 450450Serine incorporator 2
PRO_0000218969

Regions

Transmembrane5 – 2723Helical; Potential
Transmembrane40 – 5718Helical; Potential
Transmembrane96 – 11823Helical; Potential
Transmembrane131 – 15020Helical; Potential
Transmembrane160 – 18223Helical; Potential
Transmembrane203 – 22523Helical; Potential
Transmembrane238 – 25720Helical; Potential
Transmembrane264 – 28623Helical; Potential
Transmembrane315 – 33723Helical; Potential
Transmembrane380 – 40223Helical; Potential
Transmembrane417 – 43923Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q8K0E7 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: BD9111690A875B45

FASTA45050,478
        10         20         30         40         50         60 
MGACLGACSL LSCASCLCGS APCILCGCCP STRNSTVSRL LFTSFLFLGV LVSIIMLSPG 

        70         80         90        100        110        120 
VESQLYKLPW VCEDRTQQPL VLQGPLDCGS LLGFRAVYRM CFATAAFFFF FMLLMICVRS 

       130        140        150        160        170        180 
SRDPRAAIQN GFWFFKFLIL VGITVGAFYI PDGSFPKIWF YFGVVGSFLF ILIQLILFVD 

       190        200        210        220        230        240 
FAHSWNQRWL CKAEECDSPA WYAGLFFFTF LFYLLSIAAV ALMFVYYTES GACHEGKVFI 

       250        260        270        280        290        300 
SLNLTFCVCV SIIAVLPKVQ DAQPNSGLLQ ASVITLYTMF VTWSALSNVP DQKCNPHLPT 

       310        320        330        340        350        360 
KNGTGQVDLE DYSTVWWDAP SIVGLVIFIL CTFFISLRSS DHRQVNSLMQ TEECPAEMVQ 

       370        380        390        400        410        420 
QQQVAVSDGR AYDNEQDGVT YSYSFFHFCL VLASLHVMMT LTNWYSPGET RKMISTWTSV 

       430        440        450 
WVKICASWAG LFLYLWTLVA PLLLPNRDFS 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Colon.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC031720 mRNA. Translation: AAH31720.1.
RefSeqNP_766290.2. NM_172702.3.
UniGeneMm.45132.

3D structure databases

ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ8K0E7.

Proteomic databases

PRIDEQ8K0E7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000105996; ENSMUSP00000101618; ENSMUSG00000023232.
GeneID230779.
KEGGmmu:230779.
UCSCuc008uzc.1. mouse.

Organism-specific databases

CTD347735.
MGIMGI:1919132. Serinc2.

Phylogenomic databases

eggNOGNOG308011.
GeneTreeENSGT00550000074522.
HOGENOMHOG000165463.
HOVERGENHBG025699.
TreeFamTF312881.

Gene expression databases

ArrayExpressQ8K0E7.
BgeeQ8K0E7.
CleanExMM_SERINC2.
GenevestigatorQ8K0E7.

Family and domain databases

InterProIPR005016. TMS_TDE.
[Graphical view]
PANTHERPTHR10383. PTHR10383. 1 hit.
PfamPF03348. Serinc. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio380148.
PROQ8K0E7.
SOURCESearch...

Entry information

Entry nameSERC2_MOUSE
AccessionPrimary (citable) accession number: Q8K0E7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: October 1, 2002
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot