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Protein

Cytochrome c oxidase assembly protein COX19

Gene

Cox19

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be required for the assembly of mitochondrial cytochrome c oxidase.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase assembly protein COX19
Gene namesi
Name:Cox19
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1915283. Cox19.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 9291Cytochrome c oxidase assembly protein COX19PRO_0000273152Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ8K0C8.
PaxDbiQ8K0C8.
PeptideAtlasiQ8K0C8.
PRIDEiQ8K0C8.

PTM databases

PhosphoSiteiQ8K0C8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000045438.
ExpressionAtlasiQ8K0C8. baseline and differential.
GenevisibleiQ8K0C8. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062046.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 6442CHCHAdd
BLAST

Sequence similaritiesi

Belongs to the COX19 family.Curated
Contains 1 CHCH domain.Curated

Phylogenomic databases

eggNOGiKOG3477. Eukaryota.
ENOG41121W4. LUCA.
GeneTreeiENSGT00390000016895.
HOGENOMiHOG000208239.
HOVERGENiHBG081305.
InParanoidiQ8K0C8.
KOiK18183.
OMAiQLMTKEP.
OrthoDBiEOG091G10VA.
PhylomeDBiQ8K0C8.
TreeFamiTF321525.

Family and domain databases

InterProiIPR009069. Cys_alpha_HP_mot_SF.
[Graphical view]
SUPFAMiSSF47072. SSF47072. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8K0C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTAMNFGTK SFQPRPPDKG SFPLDHFGEC KSFKEKFMRC LRDKNYENAL
60 70 80 90
CRNESKEYLM CRMQRQLMAP EPLEKLGFRD LMEGKPEAKD EC
Length:92
Mass (Da):10,821
Last modified:October 1, 2002 - v1
Checksum:iB3F616804658F594
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC031792 mRNA. Translation: AAH31792.1.
CCDSiCCDS39350.1.
RefSeqiNP_932097.1. NM_197980.1.
UniGeneiMm.261064.

Genome annotation databases

EnsembliENSMUST00000049630; ENSMUSP00000062046; ENSMUSG00000045438.
GeneIDi68033.
KEGGimmu:68033.
UCSCiuc009agj.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC031792 mRNA. Translation: AAH31792.1.
CCDSiCCDS39350.1.
RefSeqiNP_932097.1. NM_197980.1.
UniGeneiMm.261064.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062046.

PTM databases

PhosphoSiteiQ8K0C8.

Proteomic databases

MaxQBiQ8K0C8.
PaxDbiQ8K0C8.
PeptideAtlasiQ8K0C8.
PRIDEiQ8K0C8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000049630; ENSMUSP00000062046; ENSMUSG00000045438.
GeneIDi68033.
KEGGimmu:68033.
UCSCiuc009agj.1. mouse.

Organism-specific databases

CTDi90639.
MGIiMGI:1915283. Cox19.

Phylogenomic databases

eggNOGiKOG3477. Eukaryota.
ENOG41121W4. LUCA.
GeneTreeiENSGT00390000016895.
HOGENOMiHOG000208239.
HOVERGENiHBG081305.
InParanoidiQ8K0C8.
KOiK18183.
OMAiQLMTKEP.
OrthoDBiEOG091G10VA.
PhylomeDBiQ8K0C8.
TreeFamiTF321525.

Miscellaneous databases

PROiQ8K0C8.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045438.
ExpressionAtlasiQ8K0C8. baseline and differential.
GenevisibleiQ8K0C8. MM.

Family and domain databases

InterProiIPR009069. Cys_alpha_HP_mot_SF.
[Graphical view]
SUPFAMiSSF47072. SSF47072. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOX19_MOUSE
AccessioniPrimary (citable) accession number: Q8K0C8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.