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Protein

Paraneoplastic antigen Ma3 homolog

Gene

Pnma3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri415 – 432CCHC-typePROSITE-ProRule annotationAdd BLAST18

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Paraneoplastic antigen Ma3 homolog
Gene namesi
Name:Pnma3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2180565. Pnma3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002802161 – 466Paraneoplastic antigen Ma3 homologAdd BLAST466

Proteomic databases

PaxDbiQ8JZW8.
PRIDEiQ8JZW8.

PTM databases

iPTMnetiQ8JZW8.
PhosphoSitePlusiQ8JZW8.

Expressioni

Tissue specificityi

Expressed in the cerebrum and cerebellum.1 Publication

Gene expression databases

BgeeiENSMUSG00000046287.
CleanExiMM_PNMA3.
GenevisibleiQ8JZW8. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054177.

Structurei

3D structure databases

ProteinModelPortaliQ8JZW8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi332 – 338Poly-Glu7
Compositional biasi385 – 392Poly-Arg8

Sequence similaritiesi

Belongs to the PNMA family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri415 – 432CCHC-typePROSITE-ProRule annotationAdd BLAST18

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410J6QQ. Eukaryota.
ENOG410Y05Y. LUCA.
GeneTreeiENSGT00530000062986.
HOGENOMiHOG000013079.
HOVERGENiHBG052488.
InParanoidiQ8JZW8.
OMAiDWCRGEH.
OrthoDBiEOG091G0BG9.
PhylomeDBiQ8JZW8.
TreeFamiTF335054.

Family and domain databases

Gene3Di4.10.60.10. 1 hit.
InterProiView protein in InterPro
IPR026523. PNMA.
IPR026529. PNMA3.
IPR001878. Znf_CCHC.
IPR036875. Znf_CCHC_sf.
PANTHERiPTHR23095. PTHR23095. 1 hit.
PTHR23095:SF22. PTHR23095:SF22. 1 hit.
PfamiView protein in Pfam
PF14893. PNMA. 1 hit.
PROSITEiView protein in PROSITE
PS50158. ZF_CCHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8JZW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLNLLQDWC RGEHLNTQRS MLILGIPEDC SEDEFEETLH EALKHLGRYR
60 70 80 90 100
IIGRMFRREE NAQAFLVELA RDFDYALVPR EIEGKGGPWE VVVKPPHSDD
110 120 130 140 150
EFLNRLNHFL EEERRTVSDM NRVLGTHSNH SPTKTTISAD FWVWAQTLGA
160 170 180 190 200
VMQPLLEQML YRELRVFSGN TISIPGLLAF DSWLEHTTEM LQMWQVPEVE
210 220 230 240 250
KRRRLMECLR GPALQVVNVL RANNAAITVK ECLEALRQVF GSVDNRKIAQ
260 270 280 290 300
LKFCKAYQEP GEKVSSFVVR LETLLQKALE KNAISRKNVN QTRLKRILGG
310 320 330 340 350
AILSAKLREK LKMLKQRRRP PGFLALVKLF REEEEEWEAT RGSERSCYEG
360 370 380 390 400
LELGPSPSNI GSEERELFVP AFGSVLEERP YQGSRRRRHR RRGQHRKGGV
410 420 430 440 450
PRDDSQGTRK QNYDTFCYSC GEDGHIRVHC FNPSNRTLVK QKRQAAMEKG
460
NRSWAWEKSH PKPKTK
Length:466
Mass (Da):54,041
Last modified:October 1, 2002 - v1
Checksum:i113787E37B0B3AAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX813330 Genomic DNA. Translation: CAM13929.1.
BC036726 mRNA. Translation: AAH36726.1.
AK141560 mRNA. Translation: BAE24735.1.
CCDSiCCDS30192.1.
RefSeqiNP_694809.1. NM_153169.2.
UniGeneiMm.256249.

Genome annotation databases

EnsembliENSMUST00000060418; ENSMUSP00000054177; ENSMUSG00000046287.
GeneIDi245468.
KEGGimmu:245468.
UCSCiuc009tla.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiPNMA3_MOUSE
AccessioniPrimary (citable) accession number: Q8JZW8
Secondary accession number(s): Q3URF3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 1, 2002
Last modified: October 25, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families