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Protein
Submitted name:

Adapter molecule crk

Gene

Crk

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Adapter molecule crkImported
Submitted name:
Crk proteinImported
Submitted name:
V-crk sarcoma virus CT10 oncogene homolog (Avian), isoform CRA_cImported
Gene namesi
Name:CrkImported
ORF Names:mCG_10785Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:88508. Crk.

Expressioni

Gene expression databases

BgeeiENSMUSG00000017776.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000017920.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 118106SH2InterPro annotationAdd
BLAST
Domaini132 – 19261SH3InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation
Contains SH2 domain.SAAS annotation

Keywords - Domaini

SH3 domainUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4792. Eukaryota.
ENOG4110574. LUCA.
GeneTreeiENSGT00820000127055.
HOGENOMiHOG000236288.
HOVERGENiHBG105616.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiSM00252. SH2. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 2 hits.
PROSITEiPS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8JZR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS
60 70 80 90 100
VSENSRVSHY IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL
110 120 130 140 150
LEFYKIHYLD TTTLIEPVAR SRQGSGVILR QEEAEYVRAL FDFNGNDEED
160 170 180 190 200
LPFKKGDILR IRDKPEEQWW NAEDSEGKRG MIPVPYVEKY RPASASVSAL

IGGR
Length:204
Mass (Da):22,890
Last modified:October 1, 2002 - v1
Checksum:i25F7AC1188657461
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591440 Genomic DNA. No translation available.
BC031149 mRNA. Translation: AAH31149.1.
AK028179 mRNA. Translation: BAC25792.1.
AK036905 mRNA. Translation: BAC29633.1.
AK052795 mRNA. Translation: BAC35149.1.
AK088519 mRNA. Translation: BAC40399.1.
AK139089 mRNA. Translation: BAE23885.1.
CH466596 Genomic DNA. Translation: EDL12836.1.
RefSeqiNP_001264148.1. NM_001277219.1.
UniGeneiMm.280125.

Genome annotation databases

EnsembliENSMUST00000108425; ENSMUSP00000104063; ENSMUSG00000017776.
GeneIDi12928.
UCSCiuc007kes.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591440 Genomic DNA. No translation available.
BC031149 mRNA. Translation: AAH31149.1.
AK028179 mRNA. Translation: BAC25792.1.
AK036905 mRNA. Translation: BAC29633.1.
AK052795 mRNA. Translation: BAC35149.1.
AK088519 mRNA. Translation: BAC40399.1.
AK139089 mRNA. Translation: BAE23885.1.
CH466596 Genomic DNA. Translation: EDL12836.1.
RefSeqiNP_001264148.1. NM_001277219.1.
UniGeneiMm.280125.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000017920.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000108425; ENSMUSP00000104063; ENSMUSG00000017776.
GeneIDi12928.
UCSCiuc007kes.2. mouse.

Organism-specific databases

CTDi1398.
MGIiMGI:88508. Crk.

Phylogenomic databases

eggNOGiKOG4792. Eukaryota.
ENOG4110574. LUCA.
GeneTreeiENSGT00820000127055.
HOGENOMiHOG000236288.
HOVERGENiHBG105616.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000017776.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiSM00252. SH2. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 2 hits.
PROSITEiPS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8JZR2_MOUSE
AccessioniPrimary (citable) accession number: Q8JZR2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.