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Protein
Submitted name:

Adapter molecule crk

Gene

Crk

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Adapter molecule crkImported
Submitted name:
Crk proteinImported
Submitted name:
V-crk sarcoma virus CT10 oncogene homolog (Avian), isoform CRA_cImported
Gene namesi
Name:CrkImported
ORF Names:mCG_10785Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:88508. Crk.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000017776.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 118SH2InterPro annotationAdd BLAST106
Domaini132 – 192SH3InterPro annotationAdd BLAST61

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4792. Eukaryota.
ENOG4110574. LUCA.
GeneTreeiENSGT00820000127055.
HOGENOMiHOG000236288.
HOVERGENiHBG105616.

Family and domain databases

CDDicd11758. SH3_CRK_N. 1 hit.
Gene3Di3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR035457. CRK_SH3_N.
IPR000980. SH2.
IPR036860. SH2_dom_sf.
IPR036028. SH3-like_dom_sf.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 2 hits.
PROSITEiView protein in PROSITE
PS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8JZR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS
60 70 80 90 100
VSENSRVSHY IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL
110 120 130 140 150
LEFYKIHYLD TTTLIEPVAR SRQGSGVILR QEEAEYVRAL FDFNGNDEED
160 170 180 190 200
LPFKKGDILR IRDKPEEQWW NAEDSEGKRG MIPVPYVEKY RPASASVSAL

IGGR
Length:204
Mass (Da):22,890
Last modified:October 1, 2002 - v1
Checksum:i25F7AC1188657461
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591440 Genomic DNA. No translation available.
BC031149 mRNA. Translation: AAH31149.1.
AK028179 mRNA. Translation: BAC25792.1.
AK036905 mRNA. Translation: BAC29633.1.
AK052795 mRNA. Translation: BAC35149.1.
AK088519 mRNA. Translation: BAC40399.1.
AK139089 mRNA. Translation: BAE23885.1.
CH466596 Genomic DNA. Translation: EDL12836.1.
RefSeqiNP_001264148.1. NM_001277219.1.
UniGeneiMm.280125.

Genome annotation databases

EnsembliENSMUST00000108425; ENSMUSP00000104063; ENSMUSG00000017776.
GeneIDi12928.
UCSCiuc007kes.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8JZR2_MOUSE
AccessioniPrimary (citable) accession number: Q8JZR2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: November 22, 2017
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported