Q8JU67 (Q8JU67_9REOV) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Putative outer capsid VP4 EMBL AAM92737.1
Organism	Grass carp reovirus EMBL AAM92737.1
Taxonomic identifier	128987 [NCBI]
Taxonomic lineage	Viruses › dsRNA viruses › Reoviridae › Spinareovirinae › Aquareovirus › Aquareovirus C

Protein attributes

Sequence length	648 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 3IYL PDB 3K1Q
Gene Ontology (GO)
Biological_process	pathogenesis Inferred from electronic annotation. Source: InterPro viral entry into host cell Inferred from electronic annotation. Source: InterPro
Cellular_component	viral capsid Inferred from electronic annotation. Source: InterPro
Molecular_function	cell surface binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8JU67 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: B0EE242233903F4B	FASTA	648	68,597
	10 20 30 40 50 60 MGNVQTSVNT YNITGDGNSF TPTSDMTSTA APAIDLKPGV LNPTGKLWRP VGTSVATIDS 70 80 90 100 110 120 LAIVSDRFGQ YSFVNEGMRE TFSKALFDIN MWQPLFQATK TGCGPIVLSS FTTTTSGYVG 130 140 150 160 170 180 ATAGDALDNP VTNGVFISTV QIMNLQRTIA ARMRDVALWQ KHLDTAMTML TPDISAGSAS 190 200 210 220 230 240 CNWKSLLAFA KDILPLDNLC LTYPNEFYNV AIHRYPALKP GNPDTKLPDA QAHPLGEVAG 250 260 270 280 290 300 AFNAATSEVG SLVGSSSTLS QAISTMAGKD LDLIEADTPL PVSVFTPSLA PRSYRPAFIK 310 320 330 340 350 360 PEDAKWIAEF NNSSLIRKTL TYSGATYTVQ LGPGPTRVID MNAMIDSVLT LDVSGTILPY 370 380 390 400 410 420 DTNPDLSTSV PAFVLIQTSV PIQQVTTAAN ITAITVVSAA GASAINLAIN VRGQPRFNML 430 440 450 460 470 480 HLQATFERET ITGIPYIYGL GTFLIPSPTS SSNFSNPTLM DGLLTVTPVL LRETTYKGEV 490 500 510 520 530 540 VDAIVPATVM ANQTSEEVAS ALANDAIVLV SNHLNKLANV VGDAIPVASR TDDSATSAIV 550 560 570 580 590 600 SRLAVQHKLS QVGQASPTPP DYPLLWRRAK RAASMFVSNP SLALQVGIPV LTQSGMLSAL 610 620 630 640 TSGVGTALRT GSLGKGVTDA SEKLRARQSL TVAKQAFFDQ IGSLWPGK

References

[1]	"Common evolutionary origin of aquareoviruses and orthoreoviruses revealed by genome characterization of Golden shiner reovirus, Grass carp reovirus, Striped bass reovirus and golden ide reovirus (genus Aquareovirus, family Reoviridae)." Attoui H., Fang Q., Mohd Jaafar F., Cantaloube J.F., Biagini P., de Micco P., de Lamballerie X. J. Gen. Virol. 83:1941-1951(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: GCRV-873 EMBL AAM92737.1.
[2]	"3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry." Zhang X., Jin L., Fang Q., Hui W.H., Zhou Z.H. Cell 141:472-482(2010) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY ELECTRON MICROSCOPY (3.30 ANGSTROMS).
[3]	"Backbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics." Cheng L., Zhu J., Hui W.H., Zhang X., Honig B., Fang Q., Zhou Z.H. J. Mol. Biol. 397:852-863(2010) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY ELECTRON MICROSCOPY (4.50 ANGSTROMS) OF 10-648.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF403392 Genomic RNA. Translation: AAM92737.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IYL	electron microscopy	3.30	A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T	1-648	[»]
3K1Q	electron microscopy	4.50	I/J/K/O/P/Q/U/V/W/X	10-648	[»]

ProteinModelPortal

Q8JU67.

SMR

Q8JU67. Positions 10-42.

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

1.10.2040.10. 2 hits.
2.60.120.420. 1 hit.

InterPro

IPR009113. Mu1/VP4.
IPR015962. Mu1_membr_pen_a-bundle_sub2.
IPR015960. Mu1_membr_pen_b-sand_sub.
[Graphical view]

Pfam

PF05993. Reovirus_M2. 1 hit.
[Graphical view]

SUPFAM

SSF69908. Mu1_membr_pen. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q8JU67.

Entry information

Entry name

Q8JU67_9REOV

Accession

Primary (citable) accession number: Q8JU67

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)