Q8JU59 (VNS1_AQRVC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Non-structural protein 1
Short name=NS1

Gene names

Name:

S4

Organism

Aquareovirus C (isolate Golden shiner/USA/GSRV/1977) (AQRV-C) [Reference proteome]

Taxonomic identifier

185783 [NCBI]

Taxonomic lineage

Viruses › dsRNA viruses › Reoviridae › Spinareovirinae › Aquareovirus › Aquareovirus C

Protein attributes

Sequence length	742 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Non-structural protein with ssRNA-binding activity. Is probably involved in the formation of viral inclusions, where the assembly of cores and the replication of viral RNA are thought to occur By similarity.
Sequence similarities	Belongs to the aquareoviridae NS1 protein family.

Ontologies

Keywords
Domain	Coiled coil
Ligand	RNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 742	742	Non-structural protein 1		PRO_0000404174
Regions
	Coiled coil	635 – 700	66	Potential
	Compositional bias	189 – 193	5	Poly-Pro

Sequences

	Sequence		Length	Mass (Da)
	Q8JU59 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: D9F7B5429E11A4D4	FASTA	742	79,460
	10 20 30 40 50 60 MARRITLNSL KPLSAMSNHP SLTPTTTPTA ATASTSTAPS IDSSTAPSLP STFNQMIFEF 70 80 90 100 110 120 NGVKYTGAPH AWMMPYRGFE QHMVNMVIET RPDATFSRFD DLLSAIVTAL AVNGITATTS 130 140 150 160 170 180 LTDGELVLLR FADLATRHAS LPSPSPAISD WSQSVPGPLL DTLEYGAPLI PAEPTATPAP 190 200 210 220 230 240 TPLAPADYPP PPPHVADPAV SHSLVALDVP DAALPSMPRA STSTASIPSL MSLPIASPPR 250 260 270 280 290 300 SRSSTLSSST STSTPRLPGT VVPRRPSHIA DDETYNRSRA AYAMGVPAMS PMYCTGKERH 310 320 330 340 350 360 FEQTFYSAYP HAANGVWTAY QHSIILIAAP TEDISLLTLH NVEREQSATE AYHLRALDGA 370 380 390 400 410 420 TVARVAVFRL APTMTCHDVH AMMAGHNVVS ISGLAAAFMI RHKLTDGVFS KSFRRIVMGI 430 440 450 460 470 480 DPVMMRHDPV PLHLFAILTD HRLDHAATHA VMSMRLALMQ IESASYQATK AWLRGHLPVT 490 500 510 520 530 540 IFASATTDSS SDSIHATILE ADKGMRVADT PGSSTLRELE ASNTALQRQV IDMDVQINAL 550 560 570 580 590 600 LRTISDLKSY TNHQQASHGY SIQQYLHSHT CVNTQELPLI QSVMGDQAAN AIQAMRTHAN 610 620 630 640 650 660 EAARSALTDK VTAPLTAQLS DTMAHLHEAR AHNGDLTAQL AIAETDAMTA ANERDRACEL 670 680 690 700 710 720 AVELESQLAT MQREYDQTTR ALLQDNEQLQ HSAATAEAAA VSAFRPTPPL TYGTAPSALP 730 740 AVGPGLTVPL LAAAIDPASL LL

References

[1]

"Common evolutionary origin of aquareoviruses and orthoreoviruses revealed by genome characterization of Golden shiner reovirus, Grass carp reovirus, Striped bass reovirus and golden ide reovirus (genus Aquareovirus, family Reoviridae)." Attoui H., Fang Q., Mohd Jaafar F., Cantaloube J.F., Biagini P., de Micco P., de Lamballerie X. J. Gen. Virol. 83:1941-1951(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF403401 Genomic RNA. Translation: AAM92747.1.
RefSeq	NP_938063.1. NC_005169.1.
3D structure databases
ProteinModelPortal	Q8JU59.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2648332.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

VNS1_AQRVC

Accession

Primary (citable) accession number: Q8JU59

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 8, 2011
Last sequence update:	October 1, 2002
Last modified:	April 3, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program