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Q8JMT1

- P19_PLV

UniProt

Q8JMT1 - P19_PLV

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Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Pear latent virus (PeLV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Suppressor of RNA silencing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene namesi
ORF Names:ORF4
OrganismiPear latent virus (PeLV)
Taxonomic identifieri197112 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiPyrus communis (Pear) (Pyrus domestica) [TaxID: 23211]

Subcellular locationi

GO - Cellular componenti

  1. virion Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172RNA silencing suppressor p19PRO_0000222876Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ8JMT1.
SMRiQ8JMT1. Positions 9-152.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tombusvirus protein p19 family.Curated

Family and domain databases

InterProiIPR004905. Tombusvirus_p19.
[Graphical view]
PfamiPF03220. Tombus_P19. 1 hit.
[Graphical view]
ProDomiPD005743. Tombus_P19. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF103145. SSF103145. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8JMT1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERAIQGSDA REQAYSERWD GGCGGTITPF KLPDESPSLI EWRLHNSEES
60 70 80 90 100
EDKDNPLGFK ESWSFGKVVF KRYLRYDGTE ASLHRALGSW ERDTVNNAAS
110 120 130 140 150
RFLGFGQIGC TYCIRFRGSC LTISGGSRTL QRLIEMAIRT KRTMLQLTPC
160 170
EVEGNVSRGS PEGTEAFKEE SE
Length:172
Mass (Da):19,357
Last modified:October 1, 2002 - v1
Checksum:iA9596921EB5E6514
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY100482 Genomic RNA. Translation: AAM49806.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY100482 Genomic RNA. Translation: AAM49806.1 .

3D structure databases

ProteinModelPortali Q8JMT1.
SMRi Q8JMT1. Positions 9-152.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR004905. Tombusvirus_p19.
[Graphical view ]
Pfami PF03220. Tombus_P19. 1 hit.
[Graphical view ]
ProDomi PD005743. Tombus_P19. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF103145. SSF103145. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Molecular characterization of a tombusvirus isolated from diseased pear trees in southern Italy."
    Russo M., Vovlas C., Rubino L., Grieco F., Martelli G.P.
    J. Plant Pathol. 84:161-166(2002)
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiP19_PLV
AccessioniPrimary (citable) accession number: Q8JMT1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3