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Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Pear latent virus (PeLV)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).By similarity

GO - Molecular functioni

Keywordsi

Molecular functionRNA-binding, Suppressor of RNA silencing

Names & Taxonomyi

Protein namesi
Recommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene namesi
ORF Names:ORF4
OrganismiPear latent virus (PeLV)
Taxonomic identifieri197112 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiPyrus communis (Pear) (Pyrus domestica) [TaxID: 23211]
Proteomesi
  • UP000232449 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002228761 – 172RNA silencing suppressor p19Add BLAST172

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ8JMT1
SMRiQ8JMT1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tombusvirus protein p19 family.Curated

Family and domain databases

Gene3Di2.60.40.1810, 1 hit
InterProiView protein in InterPro
IPR004905 Tombusvirus_p19
IPR036131 VP19_sf
PfamiView protein in Pfam
PF03220 Tombus_P19, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005743 Tombus_P19, 1 hit
SUPFAMiSSF103145 SSF103145, 1 hit

Sequencei

Sequence statusi: Complete.

Q8JMT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERAIQGSDA REQAYSERWD GGCGGTITPF KLPDESPSLI EWRLHNSEES
60 70 80 90 100
EDKDNPLGFK ESWSFGKVVF KRYLRYDGTE ASLHRALGSW ERDTVNNAAS
110 120 130 140 150
RFLGFGQIGC TYCIRFRGSC LTISGGSRTL QRLIEMAIRT KRTMLQLTPC
160 170
EVEGNVSRGS PEGTEAFKEE SE
Length:172
Mass (Da):19,357
Last modified:October 1, 2002 - v1
Checksum:iA9596921EB5E6514
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY100482 Genomic RNA Translation: AAM49806.1

Similar proteinsi

Entry informationi

Entry nameiP19_PLV
AccessioniPrimary (citable) accession number: Q8JMT1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health