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Q8JLF5 (GLRX1_ECTVM) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutaredoxin-1
Gene names
Ordered Locus Names:EVM053
OrganismEctromelia virus (strain Moscow) (ECTV) (Mousepox virus)
Taxonomic identifier265874 [NCBI]
Taxonomic lineageViruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Orthopoxvirus
Virus hostMus musculus (Mouse) [TaxID: 10090]

Protein attributes

Sequence length108 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Has thioltransferase and dehydroascorbate reductase activities By similarity.

Subcellular location

Virion. Note: Localizes to the virion core By similarity.

Sequence similarities

Belongs to the glutaredoxin family.

Contains 1 glutaredoxin domain.

Ontologies

Keywords
   Biological processElectron transport
Transport
   Cellular componentVirion
   DomainRedox-active center
   PTMDisulfide bond
   Technical term3D-structure
Gene Ontology (GO)
   Biological processcell redox homeostasis

Inferred from electronic annotation. Source: InterPro

electron transport chain

Inferred from electronic annotation. Source: UniProtKB-KW

transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentvirion

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionelectron carrier activity

Inferred from electronic annotation. Source: InterPro

protein disulfide oxidoreductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 108108Glutaredoxin-1
PRO_0000141624

Regions

Domain3 – 106104Glutaredoxin

Amino acid modifications

Disulfide bond23 ↔ 26Redox-active By similarity

Secondary structure

1 ................... 108
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q8JLF5 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 92BA76087D7F54D4

FASTA10812,327
        10         20         30         40         50         60 
MAEEFVQQRL ANNKVTIFVK YTCPFCRNAL DILNKFSFKR GAYEIVDIKE FKPENELRDY 

        70         80         90        100 
FEQITGGKTV PRIFFGKTSI GGYSDLLEID NMDALGDILS SIGVLRTC

« Hide

References

[1]"The genomic sequence of Ectromelia virus, the causative agent of mousepox."
Chen N., Danila M.I., Feng Z., Buller R.M., Wang C., Han X., Lefkowitz E.J., Upton C.
Virology 317:165-186(2003) [PubMed: 14675635] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF012825 Genomic DNA. Translation: AAM92357.1.
RefSeqNP_671571.1. NC_004105.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2HZEX-ray1.80A/B1-108[»]
2HZFX-ray1.80A/B1-108[»]
ProteinModelPortalQ8JLF5.
SMRQ8JLF5. Positions 1-107.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID951620.

Phylogenomic databases

ProtClustDBPHA3050.

Family and domain databases

InterProIPR011767. GLR_AS.
IPR002109. Glutaredoxin.
IPR011899. Glutaredoxin_euk/vir.
IPR014025. Glutaredoxin_subgr.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
Gene3DG3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PfamPF00462. Glutaredoxin. 1 hit.
[Graphical view]
PRINTSPR00160. GLUTAREDOXIN.
SUPFAMSSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMsTIGR02180. GRX_euk. 1 hit.
PROSITEPS00195. GLUTAREDOXIN_1. 1 hit.
PS51354. GLUTAREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLRX1_ECTVM
AccessionPrimary (citable) accession number: Q8JLF5
Entry history
Integrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: October 1, 2002
Last modified: January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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