Q8JHV7 (Q8JHV7_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Laminin beta 1 EMBL AAM61767.1

Gene names

Name:

lamb1 EMBL AAM61767.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAM61767.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	1785 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Laminin EGF-like domain SAAS SAAS002049 Repeat SAAS SAAS002049
PTM	Disulfide bond SAAS SAAS002049
Gene Ontology (GO)
Biological process	detection of light stimulus involved in visual perception Inferred from mutant phenotype. Source: ZFIN muscle organ development Inferred from mutant phenotype. Source: ZFIN optokinetic behavior Inferred from mutant phenotype. Source: ZFIN retinal ganglion cell axon guidance Inferred from mutant phenotype. Source: ZFIN
Cellular component	perinuclear region of cytoplasm Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8JHV7 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 1BD338A0B6AB9F26	FASTA	1,785	197,280
	10 20 30 40 50 60 MLLQLAALSI LGAWALADVP ELGDVCTEGS CYPATGDLLI GRAQQLLATS TCGVHKPEPF 70 80 90 100 110 120 CIVSHLQEEK KCFVCDSRQA YNETAHQVTS HSIENVVTTF APNRLKTWWQ SENGLENVTI 130 140 150 160 170 180 QLDLEAEFHF THLIMTFKTF RPAAMVIERS ADFGNTWQVY RYFAYDCESS FPSVSHGPMT 190 200 210 220 230 240 KVDDVICDTR YSDIEPSTEG EVIFRVLDPA FRIEDPYSPR IQNMLKITNL RVKFTKLHTL 250 260 270 280 290 300 GDNLLDSRIE IKEKYYYAIY DMVVRGNCFC YGHASECAPV DGTGEAVEGM VHGHCMCNHN 310 320 330 340 350 360 TIGLNCERCQ DFYHDLPWRP AEGRNTNACK KCHCNHHSHS CHFDMAVYRA SGNVSGGVCD 370 380 390 400 410 420 DCQHNTMGHN CEQCKPFFHQ HPEKDIRDPN ICEPCNCDPV GSLNGGVCDP MTDVSLGLIS 430 440 450 460 470 480 GQCRCKPNVE GERCDQCKQG HYGLSEDPLG CQPCTCNALG TVPGGSPCDT DSGNCYCKRL 490 500 510 520 530 540 VTGRNCDQCL PQHWGLSNDM DGCRPCDCDH GGAINNNCSP VSGQCQCREH MFGRRCDQVE 550 560 570 580 590 600 SGFYFIALDH YTYEAEEAKF GPGVTVVPRN HPQDRSPTWT GIGFVNVPEG AFLEFSIDNI 610 620 630 640 650 660 PYSMEYDLII RYEPQLPEQW EEVLMTVIRP RVITADSRCA NTMPDDDNQM VSLHPGSRYV 670 680 690 700 710 720 VLPRPVCFEE GLNYTVRLSL SLYSALSDVQ SPYTLIDSIV LMPHCKNLDI FSGSGTEGGN 730 740 750 760 770 780 LVTNSAWENF QRYRCLENSQ AVVKTPMTDI CRNYIFSVSA LLHQGVKACQ CDPQGSLSTV 790 800 810 820 830 840 CDPSGGQCQC RPNVVGRNCD RCAPATFLFX PQGCRPCDCS PEGSVHSYCH EATGQCECIA 850 860 870 880 890 900 GAYGRQCDRC LPGYWGFPNC RPCTCNGHAE QCDPQTGQCL SCRDHTTGHN CERCLGGYYG 910 920 930 940 950 960 DPVLGSGDHC RPCMCPDGPG SGRQFSGACY KSPDSSQVFC VCNQGYKGAR CEECAPGYYG 970 980 990 1000 1010 1020 NPHEVGGECR PCQCNSNIDM MDPESCDART GACVKCLYHT EGESCNRCRL GYYGNALTQS 1030 1040 1050 1060 1070 1080 CRKCVCNQMG TVEEMCPSPG NCNCDLTSGQ CLCLPNVVGQ HCDQCAPDTW NMASGKGCED 1090 1100 1110 1120 1130 1140 CDCDPNHSFG SSCNEIMGQC SCKPGFGGRT CRECRELFWG NPEVKCHACD CDPRGIAEQQ 1150 1160 1170 1180 1190 1200 CNKVTGHCVC VEGVSGPRCD TCARGYTGEF PQCERCHQCF AEWDIIVGDL TNQTHRLVQK 1210 1220 1230 1240 1250 1260 VNTIKATGIT GPYQATINNV ENSANSIRNI LAQNPATQPL TEIQGLLEQA TALMAEMNSN 1270 1280 1290 1300 1310 1320 LNLTEETLSE ISSDNNSTDT KLKSLKEEAQ KLEQTVKDLR EQVEFVKNSD IRGARASVTR 1330 1340 1350 1360 1370 1380 YYEQSQNAEI RANASTTDPY NLVNQSATLR TETEELMNQT KEEFNQRQDE FSKKLDNLAG 1390 1400 1410 1420 1430 1440 QLETLDLSEL SEKTCGSPAG SENCADSRCG GLSCVDMQGS RKCGGEGCDG LTTLAHNAWQ 1450 1460 1470 1480 1490 1500 KAKDFDLEII SAMEEVDKLS KMVSEAKVKA DEAKLNAQEV LAKTNETKKR VDSSNEELRQ 1510 1520 1530 1540 1550 1560 LIKQIRDFLT QDGADLESIE AVANEVLQMQ MPTTPAQLQN LTEEIRERVG SLTDVEDILN 1570 1580 1590 1600 1610 1620 QSAADILRAE SLLEQARKAR KEASDVKSTA EMVKEALQHA ERAQNSVAEA LKQAAVDIKG 1630 1640 1650 1660 1670 1680 TQDLLVSVES ETSDSELKLS NATRRLLKLE SDVALLKEKA LNTSISANST EKEAESINAL 1690 1700 1710 1720 1730 1740 AEQLKKDLDS ELKDKYSTVE ELITQKAEGV AEAKKRAEKL QEEARNLLLQ ASEKLQLLKN 1750 1760 1770 1780 LEKNYDQNQK LLEDKANELV DLEKAVKELL QEISHKVTVY STCLF

References

[1]	"Zebrafish mutants identify an essential role for laminins in notochord formation." Parsons M.J., Pollard S.M., Saude L., Feldman B., Coutinho P., Hirst E.M.A., Stemple D.L. Development 129:3137-3146(2002) [PubMed: 12070089] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF468049 mRNA. Translation: AAM61767.1.
IPI	IPI00485526.
RefSeq	NP_775382.1. NM_173275.1.
UniGene	Dr.76526.
3D structure databases
HSSP	HSSP built from PDB template 1NPE based on UniProtKB P02468.
ProteinModelPortal	Q8JHV7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8JHV7.
Proteomic databases
PRIDE	Q8JHV7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	286830.
KEGG	dre:286830.
Organism-specific databases
CTD	286830.
ZFIN	ZDB-GENE-021226-1. lamb1.
Phylogenomic databases
eggNOG	fiNOG04054.
GeneTree	ENSGT00560000076902.
HOVERGEN	HBG052301.
Gene expression databases
Bgee	Q8JHV7.
Family and domain databases
InterPro	IPR013032. EGF-like_reg_CS. IPR002049. EGF_laminin. IPR013015. Laminin_IV. IPR008211. Laminin_N. [Graphical view]
KO	K05636.
Pfam	PF00053. Laminin_EGF. 12 hits. PF00055. Laminin_N. 1 hit. [Graphical view]
SMART	SM00180. EGF_Lam. 13 hits. SM00136. LamNT. 1 hit. [Graphical view]
PROSITE	PS00022. EGF_1. 10 hits. PS01248. EGF_LAM_1. 12 hits. PS50027. EGF_LAM_2. 13 hits. PS51116. LAMININ_IVB. 1 hit. PS51117. LAMININ_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8JHV7_DANRE

Accession

Primary (citable) accession number: Q8JHV7

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)