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Q8JH44

- Q8JH44_DANRE

UniProt

Q8JH44 - Q8JH44_DANRE

Protein
Submitted name:

Prostaglandin G/H synthase 1

Gene

ptgs1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. peroxidase activity Source: ZFIN
    3. prostaglandin-endoperoxide synthase activity Source: ZFIN

    GO - Biological processi

    1. cellular response to organic cyclic compound Source: ZFIN
    2. kidney development Source: ZFIN
    3. response to oxidative stress Source: InterPro
    4. vasculogenesis Source: ZFIN

    Protein family/group databases

    PeroxiBasei3363. DrPGHS01.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Prostaglandin G/H synthase 1Imported
    Gene namesi
    Name:ptgs1Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

    Organism-specific databases

    ZFINiZDB-GENE-020530-1. ptgs1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8JH44.
    SMRiQ8JH44. Positions 34-583.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG000366.
    InParanoidiQ8JH44.
    KOiK00509.
    PhylomeDBiQ8JH44.

    Family and domain databases

    Gene3Di1.10.640.10. 1 hit.
    InterProiIPR029580. COX-1.
    IPR000742. EG-like_dom.
    IPR010255. Haem_peroxidase.
    IPR019791. Haem_peroxidase_animal.
    [Graphical view]
    PANTHERiPTHR11903:SF6. PTHR11903:SF6. 1 hit.
    PfamiPF03098. An_peroxidase. 1 hit.
    [Graphical view]
    PRINTSiPR00457. ANPEROXIDASE.
    SUPFAMiSSF48113. SSF48113. 1 hit.
    PROSITEiPS50026. EGF_3. 1 hit.
    PS50292. PEROXIDASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8JH44-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRECNFLLKW TVILLLSVSF CAGEESPTSS NTANPCCYYP CQNQGICVRY    50
    GLERYECDCT RTGYYGENCT IPELWTRVYR LLKPSPNVVH YILTHFDWLW 100
    DLINRSFLRD WLMRKVLTVR ANLIPSPPTY NSRYDYLNWE AYSNITYYTR 150
    ILPPVPNDCP TPMGTKGKIK LPDPKLLVEK FMLRRNFRLD PQGTNLMFAF 200
    FAQHFTHQFF KTHNRVGLGF TKGLGHGVDA GHIYGDSLDR QLELRLHKDG 250
    KLKYQVLNGD IYPPTVLHAQ VKMSYPPSVP PEQQLAIGQE VFGLLPGLGM 300
    YATLWLREHN RVCEILKQEH PTWGDEQLFQ TARLIIIGET IRIVIEEYVQ 350
    HLSGYRLKLH FDPTLLFNSQ FQYQNRISVE FNQLYHWHPL MPDSFYIDGD 400
    HIQYSKFIFN TSILTHYGLE KLVEAFSIQP AGQIGGGHNI HPVVSGVAER 450
    VIVESRELRL QPFNEYRKRF NLKPYTSFAE LTGEQEMSKE LEELYGHIDA 500
    MEFYPALLLE KTRPGAVFGE SMVEMGAPFS LKGLMGNPIC SPDYWKPSTF 550
    GGKTGFDIVN SATLKKLVCL NTKWCPYVSF HTPPSDYKPQ RTSHGEL 597
    Length:597
    Mass (Da):68,963
    Last modified:October 1, 2002 - v1
    Checksum:iA13593679926F292
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY028584 mRNA. Translation: AAK33030.1.
    RefSeqiNP_705942.1. NM_153656.1.
    UniGeneiDr.18294.

    Genome annotation databases

    GeneIDi246226.
    KEGGidre:246226.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY028584 mRNA. Translation: AAK33030.1 .
    RefSeqi NP_705942.1. NM_153656.1.
    UniGenei Dr.18294.

    3D structure databases

    ProteinModelPortali Q8JH44.
    SMRi Q8JH44. Positions 34-583.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    PeroxiBasei 3363. DrPGHS01.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 246226.
    KEGGi dre:246226.

    Organism-specific databases

    CTDi 5742.
    ZFINi ZDB-GENE-020530-1. ptgs1.

    Phylogenomic databases

    HOVERGENi HBG000366.
    InParanoidi Q8JH44.
    KOi K00509.
    PhylomeDBi Q8JH44.

    Miscellaneous databases

    NextBioi 20797213.

    Family and domain databases

    Gene3Di 1.10.640.10. 1 hit.
    InterProi IPR029580. COX-1.
    IPR000742. EG-like_dom.
    IPR010255. Haem_peroxidase.
    IPR019791. Haem_peroxidase_animal.
    [Graphical view ]
    PANTHERi PTHR11903:SF6. PTHR11903:SF6. 1 hit.
    Pfami PF03098. An_peroxidase. 1 hit.
    [Graphical view ]
    PRINTSi PR00457. ANPEROXIDASE.
    SUPFAMi SSF48113. SSF48113. 1 hit.
    PROSITEi PS50026. EGF_3. 1 hit.
    PS50292. PEROXIDASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Developmental expression of functional cyclooxygenases in zebrafish."
      Grosser T., Yusuff S., Cheskis E., Pack M.A., FitzGerald G.A.
      Proc. Natl. Acad. Sci. U.S.A. 99:8418-8423(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ8JH44_DANRE
    AccessioniPrimary (citable) accession number: Q8JH44
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)