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Q8JH43

- Q8JH43_DANRE

UniProt

Q8JH43 - Q8JH43_DANRE

Protein
Submitted name:

Prostaglandin G/H synthase 2

Gene

ptgs2a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. peroxidase activity Source: ZFIN

    GO - Biological processi

    1. cellular response to organic cyclic compound Source: ZFIN
    2. response to oxidative stress Source: InterPro

    Protein family/group databases

    PeroxiBasei3364. DrPGHS02.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Prostaglandin G/H synthase 2Imported
    Submitted name:
    Prostaglandin-endoperoxide synthase 2aImported
    Gene namesi
    Name:ptgs2aImported
    Synonyms:ptgs2Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

    Organism-specific databases

    ZFINiZDB-GENE-020530-2. ptgs2a.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG000366.
    KOiK11987.

    Family and domain databases

    Gene3Di1.10.640.10. 1 hit.
    InterProiIPR029576. COX-2.
    IPR000742. EG-like_dom.
    IPR010255. Haem_peroxidase.
    IPR019791. Haem_peroxidase_animal.
    [Graphical view]
    PANTHERiPTHR11903:SF8. PTHR11903:SF8. 1 hit.
    PfamiPF03098. An_peroxidase. 2 hits.
    [Graphical view]
    PRINTSiPR00457. ANPEROXIDASE.
    SMARTiSM00181. EGF. 1 hit.
    [Graphical view]
    SUPFAMiSSF48113. SSF48113. 1 hit.
    PROSITEiPS50026. EGF_3. 1 hit.
    PS50292. PEROXIDASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8JH43-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKLVCLVLL SSIWIFPGEG YDPCCAQPCQ NQGVCLSKGA DAYECDCTRT    50
    GYYGENCTTP ELLTRIKSAL KPRPNVVHHI LTHYKSIWDI INSISYLRDG 100
    IMRYILLSRS HLVESPPTYN ADYGYKSWEA YSNLSYYTRT LAPLPQNCPT 150
    PDLPNAKQVV EQVLLRKQFI PDPQRSSLMF AFFAQHFSHQ FFKSDFKKGP 200
    AFTKALGHGV DLGHIYGETL EVQHKLRLFK DGKLKYQVVD GEVYPPLVKD 250
    VQVEMHYPPH IPEEQKFAVG HEAFGLVPGL MMYATIWLRE HNRVCDIMKQ 300
    EHPDWDDERI FQTTRLILIG ETIKIVIEDY VQHLSGYNFK LKFDPELIFS 350
    ERFQYQNRIA AEFNTLYHWH PLLPDNFQIQ DQIYGYHQFV FNNSIVTTHG 400
    IRNMVDSFTK QTAGRVSGGR NLPPAVQGVA VKVLEQTRQM RYQSFNAYRR 450
    RFNMKPYSSF EEMTGDKDLA AQLKELYGHV DKVELYPGLL VEKSRPNSVF 500
    GETMVEMGAP YSLKGLMGNA ICSPEYWKPS TFGGKVGFDI VNSASLKKLV 550
    CLNISGPCPM VSFQVPDVKF QSSENVNSSS VHSTVNNINP TVVLNERSSE 600
    L 601
    Length:601
    Mass (Da):68,673
    Last modified:October 1, 2002 - v1
    Checksum:iA5852C56521DD0C1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC056736 mRNA. Translation: AAH56736.1.
    AY028585 mRNA. Translation: AAK33031.1.
    RefSeqiNP_705943.1. NM_153657.1.
    UniGeneiDr.113864.

    Genome annotation databases

    GeneIDi246227.
    KEGGidre:246227.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC056736 mRNA. Translation: AAH56736.1 .
    AY028585 mRNA. Translation: AAK33031.1 .
    RefSeqi NP_705943.1. NM_153657.1.
    UniGenei Dr.113864.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    PeroxiBasei 3364. DrPGHS02.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 246227.
    KEGGi dre:246227.

    Organism-specific databases

    CTDi 246227.
    ZFINi ZDB-GENE-020530-2. ptgs2a.

    Phylogenomic databases

    HOVERGENi HBG000366.
    KOi K11987.

    Miscellaneous databases

    NextBioi 20797214.

    Family and domain databases

    Gene3Di 1.10.640.10. 1 hit.
    InterProi IPR029576. COX-2.
    IPR000742. EG-like_dom.
    IPR010255. Haem_peroxidase.
    IPR019791. Haem_peroxidase_animal.
    [Graphical view ]
    PANTHERi PTHR11903:SF8. PTHR11903:SF8. 1 hit.
    Pfami PF03098. An_peroxidase. 2 hits.
    [Graphical view ]
    PRINTSi PR00457. ANPEROXIDASE.
    SMARTi SM00181. EGF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48113. SSF48113. 1 hit.
    PROSITEi PS50026. EGF_3. 1 hit.
    PS50292. PEROXIDASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Developmental expression of functional cyclooxygenases in zebrafish."
      Grosser T., Yusuff S., Cheskis E., Pack M.A., FitzGerald G.A.
      Proc. Natl. Acad. Sci. U.S.A. 99:8418-8423(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: KidneyImported.

    Entry informationi

    Entry nameiQ8JH43_DANRE
    AccessioniPrimary (citable) accession number: Q8JH43
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 96 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)