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Q8JH43

- Q8JH43_DANRE

UniProt

Q8JH43 - Q8JH43_DANRE

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Protein
Submitted name: Prostaglandin G/H synthase 2
Gene
ptgs2a, ptgs2
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. peroxidase activity Source: ZFIN

GO - Biological processi

  1. cellular response to organic cyclic compound Source: ZFIN
  2. response to oxidative stress Source: InterPro
Complete GO annotation...

Protein family/group databases

PeroxiBasei3364. DrPGHS02.

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin G/H synthase 2Imported
Submitted name:
Prostaglandin-endoperoxide synthase 2aImported
Gene namesi
Name:ptgs2aImported
Synonyms:ptgs2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-020530-2. ptgs2a.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG000366.
KOiK11987.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029576. COX-2.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF8. PTHR11903:SF8. 1 hit.
PfamiPF03098. An_peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SMARTiSM00181. EGF. 1 hit.
[Graphical view]
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8JH43-1 [UniParc]FASTAAdd to Basket

« Hide

MNKLVCLVLL SSIWIFPGEG YDPCCAQPCQ NQGVCLSKGA DAYECDCTRT    50
GYYGENCTTP ELLTRIKSAL KPRPNVVHHI LTHYKSIWDI INSISYLRDG 100
IMRYILLSRS HLVESPPTYN ADYGYKSWEA YSNLSYYTRT LAPLPQNCPT 150
PDLPNAKQVV EQVLLRKQFI PDPQRSSLMF AFFAQHFSHQ FFKSDFKKGP 200
AFTKALGHGV DLGHIYGETL EVQHKLRLFK DGKLKYQVVD GEVYPPLVKD 250
VQVEMHYPPH IPEEQKFAVG HEAFGLVPGL MMYATIWLRE HNRVCDIMKQ 300
EHPDWDDERI FQTTRLILIG ETIKIVIEDY VQHLSGYNFK LKFDPELIFS 350
ERFQYQNRIA AEFNTLYHWH PLLPDNFQIQ DQIYGYHQFV FNNSIVTTHG 400
IRNMVDSFTK QTAGRVSGGR NLPPAVQGVA VKVLEQTRQM RYQSFNAYRR 450
RFNMKPYSSF EEMTGDKDLA AQLKELYGHV DKVELYPGLL VEKSRPNSVF 500
GETMVEMGAP YSLKGLMGNA ICSPEYWKPS TFGGKVGFDI VNSASLKKLV 550
CLNISGPCPM VSFQVPDVKF QSSENVNSSS VHSTVNNINP TVVLNERSSE 600
L 601
Length:601
Mass (Da):68,673
Last modified:October 1, 2002 - v1
Checksum:iA5852C56521DD0C1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC056736 mRNA. Translation: AAH56736.1.
AY028585 mRNA. Translation: AAK33031.1.
RefSeqiNP_705943.1. NM_153657.1.
UniGeneiDr.113864.

Genome annotation databases

GeneIDi246227.
KEGGidre:246227.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC056736 mRNA. Translation: AAH56736.1 .
AY028585 mRNA. Translation: AAK33031.1 .
RefSeqi NP_705943.1. NM_153657.1.
UniGenei Dr.113864.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

PeroxiBasei 3364. DrPGHS02.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 246227.
KEGGi dre:246227.

Organism-specific databases

CTDi 246227.
ZFINi ZDB-GENE-020530-2. ptgs2a.

Phylogenomic databases

HOVERGENi HBG000366.
KOi K11987.

Miscellaneous databases

NextBioi 20797214.

Family and domain databases

Gene3Di 1.10.640.10. 1 hit.
InterProi IPR029576. COX-2.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view ]
PANTHERi PTHR11903:SF8. PTHR11903:SF8. 1 hit.
Pfami PF03098. An_peroxidase. 2 hits.
[Graphical view ]
PRINTSi PR00457. ANPEROXIDASE.
SMARTi SM00181. EGF. 1 hit.
[Graphical view ]
SUPFAMi SSF48113. SSF48113. 1 hit.
PROSITEi PS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Developmental expression of functional cyclooxygenases in zebrafish."
    Grosser T., Yusuff S., Cheskis E., Pack M.A., FitzGerald G.A.
    Proc. Natl. Acad. Sci. U.S.A. 99:8418-8423(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ8JH43_DANRE
AccessioniPrimary (citable) accession number: Q8JH43
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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