Q8JH43 (Q8JH43_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Prostaglandin G/H synthase 2 EMBL AAK33031.1

Submitted name:
Prostaglandin-endoperoxide synthase 2a EMBL AAH56736.1

Gene names

Name:	ptgs2a ZFIN ZDB-GENE-020530-2
Synonyms:	ptgs2 EMBL AAK33031.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAK33031.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	601 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	response to chemical stimulus Inferred from direct assay PubMed 17112475. Source: ZFIN response to oxidative stress Inferred from electronic annotation. Source: InterPro
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro peroxidase activity Inferred from direct assay PubMed 17112475. Source: ZFIN
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8JH43 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: A5852C56521DD0C1	FASTA	601	68,673
	10 20 30 40 50 60 MNKLVCLVLL SSIWIFPGEG YDPCCAQPCQ NQGVCLSKGA DAYECDCTRT GYYGENCTTP 70 80 90 100 110 120 ELLTRIKSAL KPRPNVVHHI LTHYKSIWDI INSISYLRDG IMRYILLSRS HLVESPPTYN 130 140 150 160 170 180 ADYGYKSWEA YSNLSYYTRT LAPLPQNCPT PDLPNAKQVV EQVLLRKQFI PDPQRSSLMF 190 200 210 220 230 240 AFFAQHFSHQ FFKSDFKKGP AFTKALGHGV DLGHIYGETL EVQHKLRLFK DGKLKYQVVD 250 260 270 280 290 300 GEVYPPLVKD VQVEMHYPPH IPEEQKFAVG HEAFGLVPGL MMYATIWLRE HNRVCDIMKQ 310 320 330 340 350 360 EHPDWDDERI FQTTRLILIG ETIKIVIEDY VQHLSGYNFK LKFDPELIFS ERFQYQNRIA 370 380 390 400 410 420 AEFNTLYHWH PLLPDNFQIQ DQIYGYHQFV FNNSIVTTHG IRNMVDSFTK QTAGRVSGGR 430 440 450 460 470 480 NLPPAVQGVA VKVLEQTRQM RYQSFNAYRR RFNMKPYSSF EEMTGDKDLA AQLKELYGHV 490 500 510 520 530 540 DKVELYPGLL VEKSRPNSVF GETMVEMGAP YSLKGLMGNA ICSPEYWKPS TFGGKVGFDI 550 560 570 580 590 600 VNSASLKKLV CLNISGPCPM VSFQVPDVKF QSSENVNSSS VHSTVNNINP TVVLNERSSE L

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Developmental expression of functional cyclooxygenases in zebrafish." Grosser T., Yusuff S., Cheskis E., Pack M.A., FitzGerald G.A. Proc. Natl. Acad. Sci. U.S.A. 99:8418-8423(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney EMBL AAH56736.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC056736 mRNA. Translation: AAH56736.1. AY028585 mRNA. Translation: AAK33031.1.
IPI	IPI00499500.
RefSeq	NP_705943.1. NM_153657.1.
UniGene	Dr.113864.
3D structure databases
HSSP	HSSP built from PDB template 1CVU based on UniProtKB Q05769.
SMR	Q8JH43. Positions 23-565.
ModBase	Search...
Protein family/group databases
PeroxiBase	3364. DrPGHS02.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	246227.
KEGG	dre:246227.
Organism-specific databases
CTD	246227.
ZFIN	ZDB-GENE-020530-2. ptgs2a.
Phylogenomic databases
HOVERGEN	HBG000366.
KO	K00509.
Family and domain databases
Gene3D	1.10.640.10. 1 hit.
InterPro	IPR000742. EG-like_dom. IPR010255. Haem_peroxidase. IPR002007. Haem_peroxidase_animal. IPR019791. Haem_peroxidase_animal_subgr. [Graphical view]
Pfam	PF03098. An_peroxidase. 1 hit. [Graphical view]
PRINTS	PR00457. ANPEROXIDASE.
SMART	SM00181. EGF. 1 hit. [Graphical view]
SUPFAM	SSF48113. Peroxidase_super. 1 hit.
PROSITE	PS50026. EGF_3. 1 hit. PS50292. PEROXIDASE_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20797214.

Entry information

Entry name

Q8JH43_DANRE

Accession

Primary (citable) accession number: Q8JH43

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	April 3, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)